Journals / Kocatepe Tıp Dergisi / 2026 / Cilt: 27 Sayı: 4

DISTRIBUTION OF ANATOMICAL LOCALIZATIONS AND VASCULAR RISK FACTORS IN ACUTE ISCHEMIC STROKE: A SINGLE-CENTER RETROSPECTIVE STUDY

AKUT İSKEMİK İNMEDE ANATOMİK LOKALİZASYONLARIN DAĞILIMI VE VASKÜLER RİSK FAKTÖRLERİ: TEK MERKEZLİ RETROSPEKTİF ÇALIŞMA

Abdullah Güzel(Afyonkarahisar Sağlık Bilimleri Üniversitesi)0000-0001-8840-6088
Pages
565–570
Publication Date
2026-10-12
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Given the diagnostic challenges of posterior circulation strokes, increased clinical awareness and appropriate imaging strategies are essential.

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: This study aimed to determine the distribution of anatomical infarct localizations (anterior, posterior, and combined circulation) and their association with clinical characteristics in patients hospitalized with acute ischemic stroke.
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Key Findings & Data:MATERIAL AND METHODS: In this single-center retrospective study, 199 consecutive patients hospitalized with acute ischemic stroke at the Neurology Department of Afyonkarahisar Health Sciences University during a one-year study period were evaluated.
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Conclusion & Impact:Given the diagnostic challenges of posterior circulation strokes, increased clinical awareness and appropriate imaging strategies are essential.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:İskemik İnme · Serebrovasküler Dolaşım · Anterior Serebral Arter İnfarktı

Abstract

OBJECTIVE: This study aimed to determine the distribution of anatomical infarct localizations (anterior, posterior, and combined circulation) and their association with clinical characteristics in patients hospitalized with acute ischemic stroke. MATERIAL AND METHODS: In this single-center retrospective study, 199 consecutive patients hospitalized with acute ischemic stroke at the Neurology Department of Afyonkarahisar Health Sciences University during a one-year study period were evaluated. Demographic data and vascular risk factors were obtained from medical records. Infarct localization was classified as anterior, posterior, or combined circulation. Categorical variables were compared using the chi-square test or Fisher’s exact test when appropriate. RESULTS: Of the patients, 49.2% were female and 50.8% were male, with a mean age of 67.7±10.8 years. Female patients were older than male patients (p=0.008). Anterior circulation infarcts were observed in 83.4% of patients, posterior circulation infarcts in 14.6%, and combined circulation involvement in 2.0%. There was no significant difference in infarct localization according to sex (p=0.786). Compared with the anterior group, the posterior group had higher rates of hypertension (p=0.039), diabetes mellitus (p<0.001), and coronary artery disease (p=0.036), whereas atrial fibrillation and smoking status were not significantly different (p=0.646 and p=0.421, respectively). CONCLUSIONS: Anterior circulation infarcts constitute the majority of acute ischemic strokes, whereas posterior circulation infarcts are less frequent. Given the diagnostic challenges of posterior circulation strokes, increased clinical awareness and appropriate imaging strategies are essential.

Özet

AMAÇ: Bu çalışmanın amacı, akut iskemik inme nedeniyle yatırılarak izlenen hastalarda enfarkt anatomik lokalizasyonlarının (anterior, posterior ve kombine) dağılımını belirlemek ve klinik özelliklerle ilişkisini incelemektir. GEREÇ VE YÖNTEM: Bu tek merkezli, retrospektif çalışmada Afyonkarahisar Sağlık Bilimleri Üniversitesi Nöroloji Servisi’nde 1 yıllık çalışma döneminde hospitalize edilen 199 ardışık akut iskemik inme olgusu değerlendirildi. Demografik veriler ve vasküler risk faktörleri hasta kayıtlarından elde edildi. Enfarkt anatomik lokalizasyonu anterior, posterior ve kombine sirkülasyon olarak sınıflandırıldı. Kategorik değişkenlerin karşılaştırılmasında Ki-kare testi veya uygun durumlarda Fisher kesin testi kullanıldı. BULGULAR: Hastaların %49,2’si kadın, %50,8’i erkekti ve yaş ortalaması 67,7±10,8 yıl idi. Kadınlarda yaş ortalaması erkeklere göre daha yüksekti (p=0,008). Olguların %83,4’ünde anterior, %14,6’sında posterior ve %2,0’ında kombine sirkülasyon enfarktı saptandı. Anatomik lokalizasyon dağılımı cinsiyet açısından anlamlı farklılık göstermedi (p=0,786). Anterior ve posterior gruplar karşılaştırıldığında posterior grupta hipertansiyon (p=0,039), diyabetes mellitus (p<0,001) ve koroner arter hastalığı (p=0,036) daha sık izlendi; atriyal fibrilasyon ve sigara kullanımı açısından fark saptanmadı (sırasıyla p=0,646 ve p=0,421). SONUÇ: Akut iskemik inmede anterior sirkülasyon enfarktları çoğunluğu oluşturmakta olup, posterior sirkülasyon enfarktları daha düşük oranda izlenmektedir. Posterior dolaşım inmelerinin tanısal güçlükleri göz önüne alındığında, klinik farkındalığın artırılması ve uygun görüntüleme stratejilerinin uygulanması önemlidir.

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Cite This Article

Güzel, A. (2026). DISTRIBUTION OF ANATOMICAL LOCALIZATIONS AND VASCULAR RISK FACTORS IN ACUTE ISCHEMIC STROKE: A SINGLE-CENTER RETROSPECTIVE STUDY. Kocatepe Tıp Dergisi, Cilt: 27 Sayı: 4, 565–570. https://doi.org/10.18229/kocatepetip.1860621

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