SavedAdd your journal

Journals / Türk Psikiyatri Dergisi / 2015 / Cilt: 26 - Sayı: 4

Cavum Vergae and Schizophrenia: Brain Imaging Findings and Treatment Outcome of a Case with 25 Years of Untreated Psychosis

Kavum Vergae ve Şizofreni: 25 Yıl Boyunca Tedavisiz Kalmış Bir Olguda Beyin Görüntüleme Bulguları ve Klinik İzlem

Berkant SAĞIR
İBRAHİM TOLGA BİNBAY
DENİZ CEYLAN TUFAN ÖZALP
Nefize YALIN
Ayşegül ÖZERDEM
Köksal ALPTEKİN
Pages
295–298
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this case report, we present cavum vergae in a schizophrenia case with a 25 year history of untreated psychosis, discuss the probable relation of psychotic symptoms to structural brain anomaly, and evaluate the treatment course

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Psychotic symptoms and disorders can emerge due to structural brain abnormalities.
📊
Key Findings & Data:Although cavum vergea is reported to be common in schizophrenia and other psychotic disorders, a significant relationship has been found only for anomalies greater than 6 mm.
💡
Conclusion & Impact:In this case report, we present cavum vergae in a schizophrenia case with a 25 year history of untreated psychosis, discuss the probable relation of psychotic symptoms to structural brain anomaly, and evaluate the treatment course
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Psychotic symptoms and disorders can emerge due to structural brain abnormalities. The septum pellucidum is one of the midline brain structures, which consists of the fusion of two thin membranes. Cavum vergae is recognized as the most severe form of fusion defect in the membranes of septum pellucidum. Although cavum vergea is reported to be common in schizophrenia and other psychotic disorders, a significant relationship has been found only for anomalies greater than 6 mm. Large cavum vergae may be a marker of developmental anomalies in other midline structures and connections, which in turn may lead to psychotic symptoms and disorders. In this case report, we present cavum vergae in a schizophrenia case with a 25 year history of untreated psychosis, discuss the probable relation of psychotic symptoms to structural brain anomaly, and evaluate the treatment course

Özet

Beyin yapısal anomalilerinde psikotik belirtiler ve bozukluklar görülebilmektedir. Beyin orta hat yapılarından olan ve iki ince zarın birleşiminde oluşan septum pellusidum, limbik sistemin bir parçasıdır. Septum pellusiduma ait iki yaprağın tamamen birleşmemesi ise "kavum vergea" olarak adlandırılmaktadır ve septum pellisidum gelişimsel anomalileri arasında en şiddetli anomali biçimi olarak kabul edilmektedir. Şizofreni ve diğer psikotik bozukluklarda "kavum vergae"nın daha yaygın olduğuna dair bildirimler bulunmakla birlikte anlamlı ilişkinin 6 mm'den daha büyük anomaliler için söz konusu olabileceği düşünülmektedir. Büyük çaplı "kavum vergae"nın diğer orta hat yapıları ve bağlantılarındaki yaygın bir gelişimsel anomalinin belirteci olabileceği ve bu nedenle psikotik belirtilere yol açabileceği öne sürülmektedir. Bu yazıda tedavisiz geçen psikoz süresi 25 yılı bulan bir şizofreni olgusunda saptanan kavum vergae anomalisi, boyutları, psikotik belirtiler ile ilişkisi ve olgunun tedavi süreci sunulmaktadır

🔖

Cite This Article

SAĞIR, B., BİNBAY, İ. T., ÖZALP, D. C. T., YALIN, N., ÖZERDEM, A., ALPTEKİN, K. (2015). Cavum Vergae and Schizophrenia: Brain Imaging Findings and Treatment Outcome of a Case with 25 Years of Untreated Psychosis. Türk Psikiyatri Dergisi, Cilt: 26 - Sayı: 4, 295–298. https://ajindex.com/articles/91738

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Alptekin K, Erkoc S, Gogus AK ve ark. (2005) Disability in schizophrenia: clinical correlates and prediction over 1-year follow-up. Psychiatry Res 135:103-11.
  2. Alptekin K, Yıldırım N ve Tunca Z (1990) Sağ temporal fossada araknoid kist saptanan bir kronik şizofreni olgusu. 26.Ulusal Psikiyatri ve Nörolojik Bilimler Kongresi. 1:255-60.
  3. Degreef G, Bogerts B, Falkai P ve ark. (1992) Increased prevalence of the cavum septum pellucidum in magnetic resonance scans and post-mortem brains of schizophrenic patients. Psychiatry Res 45:1-13.
  4. DeLisi LE, Hoff AL, Kushner M ve ark. (1993) Increased prevalence of cavum septum pellucidum in schizophrenia. Psychiatry Res 50:193-9.
  5. First MB, Spitzer RL, Williams JB ve ark. (2002) Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Patient Edition, (SCID-I/P). New York, Biometrics Research. Flashman LA, Roth RM, Pixley HS ve ark. (2007) Cavum septum pellucidum in schizophrenia: clinical and neuropsychological correlates. Psychiatry Res 154:147-55.
  6. Galarza M, Merlo AB, Ingratta A ve ark. (2004) Cavum septum pellucidum and its increased prevalence in schizophrenia: a neuroembryological classification. J Neuropsychiatry Clin Neurosci 16:41-6.
  7. Gewirtz G, Squires-Wheeler E, Sharif Z ve ark. (1994) Results of computerised tomography during first admission for psychosis. Br J Psychiatry 164:789- 95. Kay SR, Fiszbein A, Opler LA (1987) The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 13:261-76.
  8. Kohn R, Saxena S, Levav I ve ark. (2004) The treatment gap in mental health care. Bull World Health Organ 82:858-66.
  9. Liao ZL, Hu SH, Xu Y (2012) A case report on the relationship between treatment-resistant childhood-onset schizophrenia and an abnormally enlarged cavum septum pellucidum combined with cavum vergae. Chin Med J (Engl) 125:1349-51.
  10. Morgan C, Abdul-Al R, Lappin JM ve ark. (2006) Clinical and social determinants of duration of untreated psychosis in the AESOP first-episode psychosis study. Br J Psychiatry 189:446-52.
  11. Murphy J, Shevlin M, Houston J ve ark. (2012) A population based analysis of subclinical psychosis and help-seeking behavior. Schizophr Bull 38:360-7.
  12. Murray RM, Lewis SW (1987) Is schizophrenia a neurodevelopmental disorder? Br Med J (Clin Res Ed) 295:681-2.
  13. Nopoulos PC, Giedd JN, Andreasen NC ve ark. (1998) Frequency and severity of enlarged cavum septi pellucidi in childhood-onset schizophrenia. Am J Psychiatry 155:1074-9.
  14. Norman RM, Malla AK (2001) Durati