Journals / Türk Psikiyatri Dergisi / 2021 / Cilt: 32 - Sayı: 3

Retinal Scan with Optical Coherence Tomography in AdultAttention Deficit Hyperactivity Disorder

Yetişkin DEHB Olgularında Optik Koherens Tomografi ile Retina Taranması

Pages
176–182
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Hence, the quantitative and reproducible nature of Spectral Domain-OCT thickness measurements can be used as biomarkers to monitor disease progression in ADHD cases.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective:In this study, the retinal nerve fiber layer (RNFL) thicknesses were compared between adult attention deficit hyperactivity disorder (ADHD) cases and healthy controls.
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Key Findings & Data:Method:The study included adults diagnosed with ADHD based on the DSM-5 criteria and age and gender matched healthy controls.
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Conclusion & Impact:Hence, the quantitative and reproducible nature of Spectral Domain-OCT thickness measurements can be used as biomarkers to monitor disease progression in ADHD cases.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective:In this study, the retinal nerve fiber layer (RNFL) thicknesses were compared between adult attention deficit hyperactivity disorder (ADHD) cases and healthy controls. Method:The study included adults diagnosed with ADHD based on the DSM-5 criteria and age and gender matched healthy controls. Spectral area optical coherence tomography (OCT) was performed on the 52 eyes of 26 participants with ADHD and the 52 eyes of the 26 healthy control individuals. Results: Comparing the data on the 52 eyes of 26 ADHD participants and the 52 eyes of 26 healthy control participants indicated that the central macular thickness (CMT) and the RNFL thicknesses, the ganglion cell complex (GCC), the mean inner macular ring (MIRAVG) and the mean outer macular ring (MOR-AVG) thicknesses were significantly lower in the ADHD group. Conclusion:This is the first study in the literature on the RNFL thickness in adult ADHD patients. Our findings demonstrated that RNFL thickness is lower in ADHD cases as the unmyelinated axons are reduced in ADHD. Hence, the quantitative and reproducible nature of Spectral Domain-OCT thickness measurements can be used as biomarkers to monitor disease progression in ADHD cases.

Özet

Amaç: Bu çalışmada, yetişkin DEHB olgularıyla kontrol grubu arasında retina sinir lifi tabakası (RSLT) karşılaştırılmıştır. Yöntem:Çalışma grubu DSM 5 kriterlerine göre tanı almış DEHB olan yetişkinler, kontrol grubu ise herhangi bir psikiyatrik bozukluğu olmayan yaş ve cinsiyet uyumlu katılımcılardan oluşmuştur.DEHB olan 26 yetişkinin 52 gözüne ve 26 kontrolün 52 gözüne spektral alan optik koherens tomografi (OKT) yapılmıştır. Bulgular: DEHB olan 26 yetişkinin 52 gözünü ve 26 kontrolün 52 gözünü karşılaştırdık; Retina sinir lifi kalınlığı (RSLK), ganglion hücre kompleksi (GHK), santral makula kalınlığı(SMK), makula iç (MİH-ORT) ve dış halkanın (MDH-ORT) ortalama kalınlığı DEHB grubunda anlamlı derecede düşük olarak bulunmuştur. Sonuç: Bu, yetişkin DEHB’de RSLT kalınlığını inceleyen ilk çalışmadır. Bulgularımız, DEHB’de RSLT kalınlığının düşük olduğunu göstermektedir. DEHB’li yetişkinlerin retinalarında miyelinsiz aksonlar azalmıştır. SD-OKT ile yapılan nicel ve tekrarlanabilir ölçümler çocukergen DEHB vakalarında hastalığın seyrini ve ilerlemesini göstermek için bir biyobelirteç olarak kullanılabilir.

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Cite This Article

KEŞKEK, N. Ş., TÜNEL, M. (2022). Retinal Scan with Optical Coherence Tomography in AdultAttention Deficit Hyperactivity Disorder. Türk Psikiyatri Dergisi, Cilt: 32 - Sayı: 3, 176–182. https://ajindex.com/articles/655232

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