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Journals / Sağlık Bilimlerinde Değer / 2021 / Cilt: 11 Sayı: 3

Evaluation of Vitamin D and Zinc Levels in Pre-School Boys with Iron Deficiency Anemia

Demir Eksikliği Anemisi Olan Okul Öncesi Erkek Çocuklarda D Vitamini ve Çinko Düzeylerinin Değerlendirilmesi

Gürkan ÇIKIM
Filiz ALKAN BAYLAN
Pages
358–362
Publication Date
2021-09-20
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result, in this study, it was found that vitamin D and zinc levels decreased with IDA.

📌 3 Key Takeaways

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Objective & Hypothesis:OAim: In this study, it was aimed to investigate whether there is a change in zinc and vitamin D levels, considering that vitamin D and zinc levels, which play a role in many vital reactions in preschool boys with iron deficiency anemia (IDA), may also be affected and cause health problems.
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Key Findings & Data:Material and Methods: The study was performed on 30 boys (Group I) and 30 completely healthy boys (Group II) who were diagnosed with IDA in the pre-school age group of 2-6 years.
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Conclusion & Impact:As a result, in this study, it was found that vitamin D and zinc levels decreased with IDA.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Demir eksikliği anemisi · ferritin · D vitamini

Abstract

OAim: In this study, it was aimed to investigate whether there is a change in zinc and vitamin D levels, considering that vitamin D and zinc levels, which play a role in many vital reactions in preschool boys with iron deficiency anemia (IDA), may also be affected and cause health problems. Material and Methods: The study was performed on 30 boys (Group I) and 30 completely healthy boys (Group II) who were diagnosed with IDA in the pre-school age group of 2-6 years. In the study, hemoglobin (Hb), hematocrit (Htc), MCV, RDW, Iron, Iron binding, Ferritin, Zinc and vitamin D levels were evaluated. Results: In terms of vitamin D, and zinc levels; Group I levels were lower than group II (p<0.05). In addition, Hb, Htc, MCV, RDW, Iron, Iron Binding and Ferritin levels were lower in Group I, which included anemic children (p<0.05). There was a moderate, positive and statistically significant correlation between the vitamin vitamin. Conclusion: In vitamin D metabolism, since the 1-alpha hydroxylase enzyme that forms 1-25 (OH) D in the kidney contains iron, active vitamin D synthesis will be blocked in those with DEA, and the inflammatory response will be activated in vitamin D deficiency, thus, iron from the intestine to the blood. It is thought that the ferroportin protein that enables its passage will accelerate the destruction and as a result, DEA will occur. As a result, in this study, it was found that vitamin D and zinc levels decreased with IDA. Vitamin D and zinc levels were determined in preschool children with IDA, and it was thought that adding zinc along with vitamin D to the diets of these children was necessary for their health.

Özet

Amaç: Yapılan bu çalışmada, demir eksikliği anemisi (DEA) olan okul öncesi erkek çocuklarda birçok yaşamsal reaksiyonda rol oynayan D vitamini ve çinko düzeylerinin de etkilenip sağlık sorunlarına yol açabileceği düşünülerek çinko ve D vitamini düzeylerinde değişim olup olmadığının araştırılması amaçlandı. Gereç ve Yöntemler: Çalışmaya 2-6 yaş grubunda olan okul öncesi dönemdeki DEA tanısı alan 30 erkek çocuk (Grup I) ve tamamen sağlıklı 30 erkek çocukta (Grup II) yapıldı. Çalışmada, hemoglobin (Hb), hematokrit (Htc), MCV, RDW, Demir, Demir bağlama, Ferritin, Çinko, D vitamini düzeyleri değerlendirildi. Bulgular: D vitamini, Çinko düzeyleri açısından; Grup I, grup II’ye göre düşüktü (p<0.05). Ayrıca Hb, Htc, MCV, RDW, Demir, Demir Bağlama ve Ferritin düzeyleri de anemik çocukların yer aldığı Grup I’ de daha düşüktü (p<0.05). Yapılan analize göre hemoglobin değeri ile çinko düzeyleri arasında zayıf düzeyde, hemoglobin değeri ile D vitamini arasında ise orta düzeyde, pozitif yönlü ve istatistiksel olarak anlamlı bir ilişki vardı. Sonuç: D vitamini metabolizmasında, böbrekte yer alan aktif 1-25 (OH) D’yi oluşturan 1-alfa hidroksilaz enzimi demir içerdiğinden, DEA olanlarda aktif D vitamini sentezinin engelleneceği, ayrıca D vitamini eksikliğinde, inflamatuar yanıtın aktive olacağı, böylece barsaktan kana demir geçişini sağlayan ferroportin proteininin yıkımını hızlandıracağı ve neticesinde DEA meydana geleceği düşünülmektedir. Sonuç olarak bu çalışmada, DEA ile birlikte, D vitamini ve çinko düzeylerinin azaldığı tespit edildi. DEA saptanan okul öncesi çocuklarda, D vitamini ve çinko düzeylerinin belirlenerek, bu çocukların diyetlerine, D vitamini ile birlikte çinko ilave edilmesinin sağlıkları açısından gerekli olduğu düşünüldü.

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Cite This Article

ÇIKIM, G., BAYLAN, F. A. (2021). Evaluation of Vitamin D and Zinc Levels in Pre-School Boys with Iron Deficiency Anemia. Sağlık Bilimlerinde Değer, Cilt: 11 Sayı: 3, 358–362. https://ajindex.com/articles/904202

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