Journals / Türk Kadın Sağlığı ve Neonatoloji Dergisi / 2021 / Cilt: 3 Sayı: 1

Intrahepatic Cholestasis of Pregnancy

Gebeliğin intrahepatik kolestazı

Pages
12–18
Publication Date
2021-03-28
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, the intrahepatic cholestasis of pregnancy (ICP) is discussed with the current literature.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Intrahepatic cholestasis of pregnancy is the most common pregnancy-related liver disease that occurs during pregnancy.
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Key Findings & Data:It causes mortality and morbidity.
💡
Conclusion & Impact:In this review, the intrahepatic cholestasis of pregnancy (ICP) is discussed with the current literature.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:açlık safra asiti · Kolestaz · karaciğer enzimleri

Abstract

Intrahepatic cholestasis of pregnancy is the most common pregnancy-related liver disease that occurs during pregnancy. It causes mortality and morbidity. In this review, the intrahepatic cholestasis of pregnancy (ICP) is discussed with the current literature.

Özet

Gebeliğin intrahepatik kolestazı, gebelik sırasında ortaya çıkan ve gebeliğe özgü en sık görülen karaciğer hastalığıdır. Mortalite ve morbiditeye sebep olmaktadır. Bu derlemede gebelik kolestazı güncel literatür eşliğinde tartışılmıştır.

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Cite This Article

ARAT, Ö., AKŞAR, M., TOLUNAY, H. E. (2021). Intrahepatic Cholestasis of Pregnancy. Türk Kadın Sağlığı ve Neonatoloji Dergisi, Cilt: 3 Sayı: 1, 12–18. https://ajindex.com/articles/895413

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References (12)

  1. Pata O, Vardareli E, Ozcan A, et al. Intrahepatic cholestasis of pregnancy: correlation of preterm delivery with bile acids. Turk J Gastroenterol 2011; 22:602-605.
  2. Bicocca MJ, Sperling JD, Chauhan SP. Intrahepatic cholestasis of pregnancy: Review of six national and regional guidelines. Eur J Obstet Gynecol Reprod Biol 2018; 231:180-187.
  3. Glantz A, Marschall HU, Mattsson LA. Intrahepatic cholestasis of pregnancy: Relationships between bile acid levels and fetal complication rates. Hepatology 2004; 40:467-474.
  4. Reyes H, Radrigan ME, Gonzalez MC, et al. Steatorrhea in patients with intrahepatic cholestasis of pregnancy. Gastroenterology 1987; 93:584-590.
  5. Lindor K, Lee R. Intrahepatic Cholestasis of Pregnancy, UpToDate. 2019 (available on https://www.uptodate.com/contents/intrahepatic-cholestasis-of pregnancy search=Lindor K, Lee R. Intrahepatic Cholestasis of Pregnancy, UpToDate.&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1 Huang L, Zhao A, Lew JL, et al. Farnesoid X receptor activates transcription of the phospholipid pump MDR3. J Biol Chem 2003; 278:51085-951090.
  6. Milkiewicz P, Gallagher R, Chambers J, Eggington E, Weaver J, Elias E. Obstetric cholestasis with elevated gamma glutamyl transpeptidase: incidence, presentation and treatment. J Gastroenterol Hepatol 2003; 18:1283-1286.
  7. Lammert F, Marschall HU, Glantz A, Matern S. Intrahepatic cholestasis of pregnancy: molecular pathogenesis, diagnosis and management. J Hepatol 2000; 33:1012-1021.
  8. Meng LJ, Reyes H, Axelson M, et al. Progesterone metabolites and bile acids in serum of patients with intrahepatic cholestasis of pregnancy: effect of ursodeoxycholic acid therapy. Hepatology 1997; 26:1573-1579. Reyes H. Review: intrahepatic cholestasis. A puzzling disorder of pregnancy. J Gastroenterol Hepatol 1997; 12:211-216.
  9. Kauppila A, Korpela H, Mäkilä UM, Yrjänheikki E. Low serum selenium concentration and glutathione peroxidase activity in intrahepatic cholestasis of pregnancy. Br Med J (Clin Res Ed). 1987; 294(6565):150-152.
  10. Agostoni A, Gerli GC, Beretta L, et al. Erythrocyte antioxidant enzymes and selenium serum levels in an Andean population. Clin Chim Acta 1983; 133:153-157.
  11. Williamson C, Hems LM, Goulis DG, et al. Clinical outcome in a series of cases of obstetric cholestasis identified via a patient support group. BJOG 2004; 111:676-681.
  12. Alsulyman OM, Ouzounian JG, Ames-Castro M, Goodwin TM. Intrahepatic cholestasis of pregnancy: perinatal outcome associated with expectant mana