Journals / Türk Psikiyatri Dergisi / 2016 / Cilt: 27 - Sayı: 1

Validity and Reliability Studies of Modified Mini Mental State Examination (MMSE-E) For Turkish Illiterate Patients With Diagnosis of Alzheimer Disease

Eğitimsizler İçin Modifiye Edilen Mini Mental Testin (MMSE-E) Türk Toplumunda Alzheimer Hastalığı Tanısında Geçerlik ve Güvenilirlik Çalışması

Pages
41–46
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion : The total MMSE-I score was able to differentiate the AD group from the control group.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To investigate the validity and reliability of modified Mini Mental State Examination (MMSE-E) for illiterate patients in a Turkish population with Alzheimer's disease (AD).
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Key Findings & Data:Method: A total of 107 illiterate patients with Alzheimer's Disease (women: 65, men: 42) and 68 illiterate healthy volunteer subjects (women: 36, men: 32) were included in the study.
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Conclusion & Impact:Conclusion : The total MMSE-I score was able to differentiate the AD group from the control group.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To investigate the validity and reliability of modified Mini Mental State Examination (MMSE-E) for illiterate patients in a Turkish population with Alzheimer's disease (AD). Method: A total of 107 illiterate patients with Alzheimer's Disease (women: 65, men: 42) and 68 illiterate healthy volunteer subjects (women: 36, men: 32) were included in the study. MMSE-I and Geriatrics Depression Scale were performed on all subjects, Alzheimer patients were also administered Basic Activities of Daily Living (BADL). Clinical Dementia Rating (CDR) was used to determine the severity of disease, while a receiver operating characteristic (ROC) analysis was performed to analyze the cut-off scores of MMSE-I, and the positive/negative predictive values that were calculated for the optimal cut-off scores. Internal consistency was measured using Cronbach's coefficient ?. Additionally, correlations between total MMSE-I score and the CDR, B-ADL, and GDS scores were examined. Results: The MMSE-I scores significantly and inversely correlated with CDR (-0.82, p=0.000) and B-ADL scores (-0.051, p=0.000). The optimal cut-off points of MMSE-I were 23/24, which yielded a sensitivity of 99.0% - %100.0, a specificity of 98.5% - 97.0%, and an AUC of 1.0/1.0, respectively. Reliability of the MMSE-I was high (? = 0.70). Conclusion : The total MMSE-I score was able to differentiate the AD group from the control group.

Özet

Amaç: Eğitimsizler için modifiye edilmiş olan Mini Mental Test'in (MMSE-E) Türk Alzheimer popülasyonunda geçerlilik ve güvenilirliliğini araştırmak. Gereç ve Yöntem: Çalışmaya okuma-yazma bilmeyen 107 Alzheimer hastası (kadın:65, erkek:42) ile 68 (kadın:36, erkek:32) okuma-yazma bilmeyen sağlıklı gönüllü alındı. Tüm deneklere MMSE-E, ve Geriatrik Depresyon Skalası (GDS), hasta grubuna ise ek olarak Temel Günlük Yaşam Aktiviteleri ölçeği (T-GYA) uygulandı. Hastalık Klinik Demans Derecelendirme Ölçeği'ne (CDR) göre evrelendirildi. MMSE-E'nin en uygun kesme noktasını belirlemek için ROC (Receiver Operating Characteristic) analizleri yürütüldü ve en uygun kesme değeri (cut-off score) için pozitif/negatif yordayıcı değerleri hesaplandı. MMSE-E'nin iç tutarlılığı Cronbach ? katsayısı kullanılarak ölçüldü. Ayrıca MMSE-E toplam puanıyla CDR, T-GYA ve GDS ile korelasyonuna bakıldı.Bulgular: MMSE-E'nin CDR (-0.82, p=0.000) ve T-GYA (-0.051, p=0.000) ile yüksek bir korelasyonu olduğu tespit edilmiştir. En yüksek duyarlık (99.0/100.0), özgüllük (98.5/97.0) ve eğri altında kalan alan-AUC (1.0/1.0) sonuçlarına karşılık gelen MMSE-E toplam puan için kesme noktası 23/24 puan olarak belirlenmiştir. MMSE-E toplam puanı yüksek bir iç tutarlılık (? = 0.70) göstermiştir. Sonuç: MMSE-E toplam puanının Alzheimer hastalarını normal sağlıklı bireylerden ayırabildiği gözlenmiştir.

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Cite This Article

BABACANYILDIZ, G., URÖZÇELİK, E., KOLUKİSA, M., IŞIK, A. T., GÜRSOY, E., KOCAMAN, G., ÇELEBİ, A. (2016). Validity and Reliability Studies of Modified Mini Mental State Examination (MMSE-E) For Turkish Illiterate Patients With Diagnosis of Alzheimer Disease. Türk Psikiyatri Dergisi, Cilt: 27 - Sayı: 1, 41–46. https://ajindex.com/articles/88369

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