Journals / Türk Psikiyatri Dergisi / 2016 / Cilt: 27 - Sayı: 3

Evaluation of Changes in Anxiety and Depression Symptoms, and Sexual Functions in Patients Receiving Antidepressants: 3 Months-Long Naturalistic Follow-Up Study

Antidepresan İlaç Tedavisi Başlanan Hastalarda Anksiyete ve Depresyon Belirtileri ile Cinsel İşlevlerdeki Değişikliklerin Değerlendirilmesi: 3 Aylık Doğal İzlem Çalışması

Pages
161–169
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Sexual dysfunctions correlated with patients' level of functioning, separately from anxiety and depression symptoms.Results: Our study results show that the sexual dysfunction rate is quite high in psychiatric patients population.

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Objective & Hypothesis:Objective: The aim of this study was to study the change in sexual functions within 3 months period following the initiation of antidepressant treatment in psychiatry outpatients, and its relationship with the change in anxiety and depression symptoms.Material and Method: Eighty two patients, who consecutively applied to the psychiatry outpatient clinic and who were prescribed antidepressants, were included in the study.
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Key Findings & Data:Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, General Assessment of Functioning Scale and Arizona Sexual Experience Questionnaire (ASEC) were administered to the patients at the first interview, then repeated on a monthly basis during 3 months.
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Conclusion & Impact:Sexual dysfunctions correlated with patients' level of functioning, separately from anxiety and depression symptoms.Results: Our study results show that the sexual dysfunction rate is quite high in psychiatric patients population.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study was to study the change in sexual functions within 3 months period following the initiation of antidepressant treatment in psychiatry outpatients, and its relationship with the change in anxiety and depression symptoms.Material and Method: Eighty two patients, who consecutively applied to the psychiatry outpatient clinic and who were prescribed antidepressants, were included in the study. Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, General Assessment of Functioning Scale and Arizona Sexual Experience Questionnaire (ASEC) were administered to the patients at the first interview, then repeated on a monthly basis during 3 months. Results: Fifty seven of the patients (69.50 %) has been diagnosed with sexual dysfunctions prior to the antidepressant treatment. During the third month after the antidepressant treatment, 24 patients in this group (42.11%) showed no impairment in ASEC scores, whereas 33 patients' (57.89%) scores were still at impairment level. Eight patients out of 25 (32%) who weren't diagnosed with sexual dysfunctions prior to the treatment were later diagnosed with sexual dysfunctions. Sexual dysfunctions correlated with patients' level of functioning, separately from anxiety and depression symptoms.Results: Our study results show that the sexual dysfunction rate is quite high in psychiatric patients population. However, sexual dysfunctions rate which can be related to antidepressant treatment is 36%. It would be appropriate for clinicians to determine benefit-loss balance by considering patients' mental syndromes together with sexual functions

Özet

Amaç: Bu çalışmada, psikiyatri polikliniğine ayaktan başvuran ve an-tidepresan tedavi başlanan hastalarda, 3 aylık dönem boyunca ruhsal belirtilerindeki gerilemeye paralel cinsel işlevlerdeki değişim ve bu de-ğişimin anksiyete, depresyon belirtileri ile ilişkisinin araştırılması amaç-lanmıştır. Yöntem: Psikiyatri polikliniğine ardı sıra başvuran, antidepresan tedavi başlanan 82 hasta çalışmaya alınmıştır. Hastalara ilk görüşmede, 1., 2. ve 3. aylarda Hamilton Depresyon Derecelendirme Ölçeği, Hamilton Anksiyete Değerlendirme Ölçeği, İşlevselliğin Genel Değerlendirilmesi Ölçeği ve Arizona Cinsel Yaşantılar Ölçeği uygulanmıştır. Bulgular: Tedavi öncesinde hastaların 57'sinde (%69,50) cinsel işlev bozukluğu saptanmıştır. Bu gruptaki 24 hastada (%42,11) çalışma so-nunda ACYÖ puanlarına göre artık cinsel işlev bozukluğu saptanmaz-ken, 33 hastanın (%57,89) puanlarının ise halen bozukluk düzeyinde olduğu saptanmıştır. Tedavi öncesinde cinsel işlev bozukluğu olmayan gruptaki 25 hastanın 8'inde (%32) izlem sonunda cinsel işlev bozuklu-ğu saptanmıştır. Cinsel işlev bozukluğu, anksiyete ve depresif belirtiler-den bağımsız olarak hastaların işlevselliğini etkilemektedir.Sonuç: Çalışmamızın sonuçları psikiyatrik hasta popülasyonunda cinsel işlev bozukluğu oranının oldukça yüksek olduğuna işaret etmektedir. Klinisyenlerin tedavi başlangıcında ve takibinde ruhsal belirtilerinin ya-nında cinsel işlevlerini de göz önüne alarak tedavinin fayda-zarar denge-sini belirlemesi uygun olacaktır

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Cite This Article

ÜLGEN, M. G., GÜLEÇ, G. (2016). Evaluation of Changes in Anxiety and Depression Symptoms, and Sexual Functions in Patients Receiving Antidepressants: 3 Months-Long Naturalistic Follow-Up Study. Türk Psikiyatri Dergisi, Cilt: 27 - Sayı: 3, 161–169. https://ajindex.com/articles/88223

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References (13)

  1. Akdemir A, Örsel S, Dağ İ ve ark. (1996) H. Hamilton Depresyon Derecelendirme Ölçeğinin geçerliliği, güvenilirliği ve klinikte kullanımı. Psikiyatri Psikoloji Psikofarmakoloji Dergisi: 3P 4:251-259.
  2. Aksoy UM, Aksoy SG, Maner F ve ark. (2012) Sexual dysfunction in obsessive compulsive disorder and panic disorder. Psychiatr Danub 24:381-5.
  3. Aslan E, Fynes M (2008) Female sexual dysfunction. Int Urogynecol J 19:293- 305. Baldwin DS, Bridgman K, Buis C (2006) Resolution of sexual dysfunction during double-blind treatment of major depression with reboxetine or paroxetine. J Psychopharmacol 20:91-96.
  4. Baldwin DS, Moreno RA, Briley M (2008) Resolution of sexual dysfunction during acute treatment of major depression with milnacipran. Hum Psychopharmacol 23:527-32.
  5. Baldwin DS, Foong T (2013) Antidepressant drugs and sexual dysfunction. Br J Psychiatry 202:396-97.
  6. Bonierbale M, Lancon C, Tignol J (2003) The ELIXIR study: evaluation of sexual dysfunction in 4557 depressed patients in France. Curr Med Res Opin 19:114-24.
  7. Bossini L, Fortini V, Casolaro I ve ark. (2014) Sexual dysfunctions, psychiatric diseases and quality of life: a review. Psychiatr Pol 48:715-26.
  8. Clayton A, Keller A, McGarvey EL (2006) Burden of phase-specific sexual dysfunction with SSRIs. J Affect Disord 91:27-32.
  9. Çiftçi B, Biri A, Erdem A ve ark. (2005) Raloksifen Kullanımının Seksuel Fonksiyon Üzerine Etkileri. Türk Jinekoloji ve Obstetrik Derneği, Uzmanlık Sonrası Eğitim ve Güncel Gelişim Dergisi 2:103-106.
  10. Duenas H, Lee A, Brnabic AJ ve ark. (2011) Frequency of treatment-emergent sexual dysfunction and treatment effectiveness during SSRI or duloxetine therapy: 8-week data from a 6-month observational study. Int J Psychiatry Clin Pract 15:80-90. Ekselius L, von Knorring L (2001) Effect on sexual function of long-term treatment with selective serotonin reuptake inhibitors in depressed patients treated in primary care. J Clin Psychopharmacol 21:154-60.
  11. First MB, Spitzer RL, Gibbon M (1997) Structured clinical interview for DSM- IV clinical version (SCID-I/CV). Washington DC, APP. Gelenberg AJ, Dunner DL, Rothschild AJ ve ark. (2013) Sexual functioning in patients with recurrent major depressive disorder enrolled in the PREVENT study. J Nerv Ment Dis 201:266-273.
  12. Grover S, Shah R, Dutt A ve ark. (2012) Prevalence and pattern of sexual dysfunction in married females receiving antidepressants: An exploratory study. J Pharmacol Pharmacother 3:259-65.
  13. Hamilton M (1959) The Assessment of anxiety states by