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Journals / Ankara Üniversitesi Eczacılık Fakültesi Dergisi / 2023 / Cilt: 47 - Sayı: 1

INTEGRATED BIOINFORMATIC ANALYSIS TO EVALUATE TARGET GENES AND PATHWAYS IN CHRONIC LYMPHOCYTIC LEUKEMIA

ENTEGRE BİYOİNFORMATİK ANALİZ İLE KRONİK LENFOSİTİK LÖSEMİDE HEDEF GENLERİN VE YOLAKLARIN BELİRLENMESİ

Buket ALTINOK GÜNEŞ
Pages
239–249
Publication Date
2023-01-20
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The goal of this research was to use bioinformatic analysis to comprehend the molecular mechanisms causing CLL and to investigate potential targets for the diagnosis and therapy of CLL.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The most common type of leukemia, chronic lymphocytic leukemia (CLL), is characterized by progressive accumulation of monoclonal B cells with a specific immunophenotype in the blood, bone marrow, and lymphoid organ.
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Key Findings & Data:Objective: The most common type of leukemia, chronic lymphocytic leukemia (CLL), is characterized by progressive accumulation of monoclonal B cells with a specific immunophenotype in the blood, bone marrow, and lymphoid organ.
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Conclusion & Impact:The goal of this research was to use bioinformatic analysis to comprehend the molecular mechanisms causing CLL and to investigate potential targets for the diagnosis and therapy of CLL.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Bioinformatic analysis · CLL · GEO

Abstract

Objective: The most common type of leukemia, chronic lymphocytic leukemia (CLL), is characterized by progressive accumulation of monoclonal B cells with a specific immunophenotype in the blood, bone marrow, and lymphoid organ. The goal of this research was to use bioinformatic analysis to comprehend the molecular mechanisms causing CLL and to investigate potential targets for the diagnosis and therapy of CLL.

Özet

Amaç: En yaygın lösemi türü olan kronik lenfositik lösemi (KLL), kanda, kemik iliğinde ve lenfoid organda spesifik bir immünofenotipe sahip monoklonal B hücrelerinin ilerleyici birikimi ile karakterize edilir. Bu çalışmanın amacı, biyoinformatik analiz yaparak KLL’nin altında yatan moleküler mekanizmaları araştırmak, KLL tanı ve tedavisi için potansiyel hedefleri belirlemektir.

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Cite This Article

GÜNEŞ, B. A. (2023). INTEGRATED BIOINFORMATIC ANALYSIS TO EVALUATE TARGET GENES AND PATHWAYS IN CHRONIC LYMPHOCYTIC LEUKEMIA. Ankara Üniversitesi Eczacılık Fakültesi Dergisi, Cilt: 47 - Sayı: 1, 239–249. https://ajindex.com/articles/878130

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References (1)

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