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Journals / Turkish Computational and Theoretical Chemistry / 2022 / Cilt: 6 - Sayı: 2

A theoretical study of oleuropein derivatives as drugs

Faik GÖKALP
Ramazan ERENLER
Pages
18–21
Publication Date
2022-12-15
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The quantum calculations revealed that 2H-oleuropein (3) and 4-aminobutyl-2-oleuropein (2) were unstable and were prone to react to the radical compounds.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Oleuropein is a natural product revealing a large variety of biological activity.
📊
Key Findings & Data:The natural products are functionalized to increase the activity in the pharmaceutical industry.
💡
Conclusion & Impact:The quantum calculations revealed that 2H-oleuropein (3) and 4-aminobutyl-2-oleuropein (2) were unstable and were prone to react to the radical compounds.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Oleuropein · Gaussian · 2H-oleuropein

Abstract

Oleuropein is a natural product revealing a large variety of biological activity. The natural products are functionalized to increase the activity in the pharmaceutical industry. Theoretical calculations were carried out for oleuropein derivatives to display the target compound exhibiting the most biological effects. Hence, synthetic chemists are able to get inspired to synthesize the most active oleuropein derivatives. The chemical properties of oleuropein derivatives have been investigated theoretically. Gaussian method was used for quantum calculations of these compounds. The properties of compounds were presented and the utilization of these compounds in pharmaceutical industries was investigated. The quantum calculations revealed that 2H-oleuropein (3) and 4-aminobutyl-2-oleuropein (2) were unstable and were prone to react to the radical compounds.

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Cite This Article

GÖKALP, F., ERENLER, R. (2022). A theoretical study of oleuropein derivatives as drugs. Turkish Computational and Theoretical Chemistry, Cilt: 6 - Sayı: 2, 18–21. https://ajindex.com/articles/870899

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References (1)

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