Journals / Journal of Research in Veterinary Medicine / 2022 / Cilt: 41 - Sayı: 2

Comparison of the Efficacy of Enrofloxacin and Lactobacillus Plantarum Cell-Free Supernatant Treatments on Vaginitis in Ewes

Pages
105–111
Publication Date
2022-12-31
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The time-dependent alteration was significant for the mean bacterial and Enterobacteriaceae count in all groups (P

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of the study was to investigate the effect of different intravaginal treatment strategies on the vaginal discharge score, vaginal microbiota, bacterial and Enterobacteriaceae counts in nulliparous Merino ewes.
📊
Key Findings & Data:All ewes (n=45) received intravaginal sponges containing 60 mg medroxyprogesterone acetate for 7 days and allocated into three equal groups (n=15).
💡
Conclusion & Impact:The time-dependent alteration was significant for the mean bacterial and Enterobacteriaceae count in all groups (P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Antibiotic · Bacterial count · Lactobacillus plantarum

Abstract

The aim of the study was to investigate the effect of different intravaginal treatment strategies on the vaginal discharge score, vaginal microbiota, bacterial and Enterobacteriaceae counts in nulliparous Merino ewes. All ewes (n=45) received intravaginal sponges containing 60 mg medroxyprogesterone acetate for 7 days and allocated into three equal groups (n=15). Sponges were injected Lactobacillus plantarum cell-free supernatant (SUPER), enrofloxacin (ENRO), or physiologic saline (CON) prior to sponge insertion. At sponge removal, 500 IU equine chorionic gonadotropin (eCG) were administered in all ewes. For the detection of vaginal microbiota, bacterial and Enterobactericeae counts, samples were collected prior to sponge insertion, at sponge withdrawal, and 48 h later after sponge withdrawal. Vaginal discharge score was not different in ENRO (2.26±0.18) and SUPER (2.20±0.14) compared to CON (2.46±0.16). The time-dependent alteration was significant for the mean bacterial and Enterobacteriaceae count in all groups (P

🔖

Cite This Article

GÜNER, B., KISADERE, İ., TAVŞANLI, H., DEMİRBİLEK, S. K., KESKİN, A. (2022). Comparison of the Efficacy of Enrofloxacin and Lactobacillus Plantarum Cell-Free Supernatant Treatments on Vaginitis in Ewes. Journal of Research in Veterinary Medicine, Cilt: 41 - Sayı: 2, 105–111. https://ajindex.com/articles/869379

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Abecia J, Forcada F, González-bulnes A. Hormonal control of reproduction in small ruminants. Anim Reprod Sci. 2012; 130: 173–179
  2. Suárez G, Zunino P, Carol H, et al. Changes in the aerobic vaginal bacterial mucous load and assessment of the susceptibility to antibiotics after treatment with intravaginal sponges in anestrous ewes. Small Rumin Res. 2006; 63: 39–43
  3. Manes J, Campero C, Hozbor F, et al. Vaginal histological changes after using intravaginal sponges for oestrous synchronization in anoestrous ewes. Reprod Domest Anim. 2015; 50: 270–274
  4. Guner B, Saat N. Comparison of pregnancy rates after short-term and long-term synchronization protocol in ewes- Pilot study. Erciyes Üniversitesi Vet Fak Derg. 2021; 13: 69–74
  5. Gatti M, Zunino P, Ungerfeld R. Changes in the aerobic vaginal bacterial mucous load after treatment with intravaginal sponges in anoestrous ewes: Effect of medroxiprogesterone acetate and antibiotic treatment use. Reprod Domest Anim. 2011; 46: 205–208
  6. Manes J, Ríos G, Andrea M, et al. Vaginal mucus from ewes treated with progestogen sponges affects quality of ram spermatozoa. Theriogenology. 2016; 85: 856–861
  7. Gatti M, Ungerfeld R. Intravaginal sponges to synchronize estrus decrease sexual attractiveness in ewes. Theriogenology. 2012; 78: 1796–1799
  8. Ojeda-Hernández F, del Moral-Ventura S, Capataz-Tafur J, et al. Vaginal microbiota in Pelibuey sheep treated with antimicrobials at the removal of intravaginal sponges impregnated with flurogestone acetate. Small Rumin Res. 2019; 170: 116–119
  9. Quereda JJ, García-Roselló E, Barba M, et al. Use of probiotics in intravaginal sponges in sheep: A pilot study. Animals. 2020; 10
  10. Mohammed K, Nabih A, Darwish G. Efficacy of anti-microbial agents on vaginal microorganisms and reproductive performance of synchronized estrus ewes. Asian Pacific J Reprod. 2017; 6: 121–127
  11. Manes J, Fiorentino MA, Martino SS, et al. Changes in the vaginal microbiota in ewes after insertion of intravaginal sponges at different stages of the oestrous cycle. Livest Sci. 2018; 208: 55–59
  12. Oliveira JK, Martins G, Esteves LV., et al. Changes in the vaginal flora of goats following a short-term protocol of oestrus induction and synchronisation with intravaginal sponges as well as their antimicrobial sensitivity. Small Rumin Res. 2013; 113: 162–166
  13. Viñoles C, Paganoni B, Milton JTB, et al. Pregnancy rate and prolificacy after artificial insemination in ewes following synchronisation with