Journals / Cukurova University Journal of Natural and Applied Sciences / 2022 / Cilt: 1 - Sayı: 2

Investigations on the energy reserves of rat liver following oral exposures to nanoparticles

Pages
8–14
Publication Date
2022-06-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Likewise, the total energy reserves of the liver decreased (P

📌 3 Key Takeaways

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Objective & Hypothesis:The liver is the energy store of mammals and its energy budget can change due to xenobiotic stress.
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Key Findings & Data:Thus, this study was undertaken to investigate the accumulation of Al2O3, CuO and TiO2 NPs in the liver of female Wistar rats (Rattus norvegicus var. albinos) following oral administrations (0, 0.5, 5, 50 mg/kg b.w./day) for 14 days.
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Conclusion & Impact:Likewise, the total energy reserves of the liver decreased (P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Metal · Nanoparticle · Rat

Abstract

The liver is the energy store of mammals and its energy budget can change due to xenobiotic stress. There is no adequate information on the effects of nanoparticles (NPs) on the energy policy of mammals. Thus, this study was undertaken to investigate the accumulation of Al2O3, CuO and TiO2 NPs in the liver of female Wistar rats (Rattus norvegicus var. albinos) following oral administrations (0, 0.5, 5, 50 mg/kg b.w./day) for 14 days. Levels of total protein, lipid and glucose were measured to determine the energy reserves of the liver. ICP-MS (Inductively coupled plasma mass spectrometry) measurement showed that NPs accumulated in the liver, as the concentrations of Al, Cu and Ti increased sharply (P0.05) at the highest doses of Al2O3 and CuO exposures. However, total protein levels did not change (P>0.05) after any NP exposure. Likewise, the total energy reserves of the liver decreased (P

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Cite This Article

BAYKÖSE, A., CANLI, E. G., CANLI, M. (2022). Investigations on the energy reserves of rat liver following oral exposures to nanoparticles. Cukurova University Journal of Natural and Applied Sciences, Cilt: 1 - Sayı: 2, 8–14. https://ajindex.com/articles/850787

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