AI Summary & Key Takeaways
AI InsightThis study aims to prepare soft chewable lozenge formulations containing different bentonite doses by using 2 different preparation techniques (hand-rolling and molding techniques), to make quality control tests of the lozenges and to determine the degree of radiation absorption.
📌 3 Key Takeaways
Abstract
Lozenges are renewed popularity as a means of administering many different drugs and may be considered as alternatives to current dosage forms. Lozenges are solid/semi-solid dosage forms that can contain one or more active ingredients, generally prepared as aromatized and sweetened, dissolve or dispersed in the mouth, chewable, absorbable. They can be used in local treatment of mouth and throat infections or irritation to slowly release a fixed amount of drug into the oral cavity or cover the throat tissues with the drug solution, and sometimes to achieve systemic effects when the drug is well absorbed through the buccal membranes or chewed and swallowed. Recently, soft lozenges and chewable lozenges have been re-introduced into the pharmacy and their popularity is increased. At present, we are all exposed to a certain level of radiation. Scientific evidence from past events has demonstrated that any major uncontrolled release of radiation could be harmful and warrants immediate response to assess and minimize public health risks. Bentonite is a natural highly colloidal clay and is used for protection from radiation. This study aims to prepare soft chewable lozenge formulations containing different bentonite doses by using 2 different preparation techniques (hand-rolling and molding techniques), to make quality control tests of the lozenges and to determine the degree of radiation absorption.