Journals / Türk Kadın Sağlığı ve Neonatoloji Dergisi / 2022 / Cilt: 4 - Sayı: 1

Izmir Province First and Second Trimester Prenatal Screening Test Current Median Values

İzmir İli Birinci ve İkinci Trimester Prenatal Tarama Testi Güncel Medyan Verilerinin Değerlendirilmesi

Pages
1–7
Publication Date
2022-03-29
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: The current median values were low for free β-hCG and high for PAPP-A used in the first trimester screening test (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: In this study, it is aimed to calculate the current median values of prenatal screening tests performed in our laboratory and to compare them with the median values in the package program we use in risk calculation.
📊
Key Findings & Data:Material and Methods: As a result of the applications made to our hospital from İzmir province and its surroundings between May 2019 and May 2020, 3264 first trimester screening tests and 954 second trimester screening tests were retrospectively analyzed.
💡
Conclusion & Impact:Results: The current median values were low for free β-hCG and high for PAPP-A used in the first trimester screening test (p
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:hCG · PAPP-A · uE3

Abstract

Aim: In this study, it is aimed to calculate the current median values of prenatal screening tests performed in our laboratory and to compare them with the median values in the package program we use in risk calculation. Material and Methods: As a result of the applications made to our hospital from İzmir province and its surroundings between May 2019 and May 2020, 3264 first trimester screening tests and 954 second trimester screening tests were retrospectively analyzed. All parameters were studied from maternal serum in the Medical Biochemistry Laboratory of Izmir Katip Çelebi University Atatürk Training and Research Hospital. The median values and median multiples of the data obtained according to gestational weeks were calculated. These values were compared statistically with the median values in the Prisca program. Results: The current median values were low for free β-hCG and high for PAPP-A used in the first trimester screening test (p

Özet

Amaç: Bu çalışmada, laboratuvarımızda yapılan prenatal tarama testlerinin güncel medyan değerlerinin hesaplanması ve risk hesaplamada kullandığımız paket programdaki medyan değerler ile karşılaştırılması hedeflenmiştir. Gereç ve Yöntem: Mayıs 2019-Mayıs 2020 tarihleri arasında İzmir ili ve çevresinden hastanemize yapılan başvurular sonucu 3264 birinci trimester tarama testi, 954 ikinci trimester tarama testi retrospektif olarak incelendi. Tüm parametreler İzmir Katip Çelebi Üniversitesi Atatürk Eğitim Araştırma Hastanesi Tıbbi Biyokimya Laboratuvarı’nda maternal serumdan çalışıldı. Elde edilen verilerin gebelik haftalarına göre güncel medyan değerleri ve medyan katları hesaplandı. Prisca paket programındaki medyan değerler ile istatistiksel olarak karşılaştırıldı. Bulgular: Güncel medyan değerlerinin; tüm haftalarda birinci trimester tarama testinde kullanılan free β-hCG için düşük, PAPP-A için yüksek olduğu, ikinci trimester tarama testinde kullanılan total β-hCG için 19. hafta dışında düşük olduğu görüldü (p

🔖

Cite This Article

ÜĞE, M., DEMİR, L., AKSUN, S. (2022). Izmir Province First and Second Trimester Prenatal Screening Test Current Median Values. Türk Kadın Sağlığı ve Neonatoloji Dergisi, Cilt: 4 - Sayı: 1, 1–7. https://ajindex.com/articles/811650

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Wald N J, Kennard A, Hackshaw A, McGuire. A Antenatal Screening for Down’s Syndrome. J Med Screen 1997;4(4):181-246.
  2. Rosen T, D’Alton ME. Down Syndrome screening in the first and second trimesters: What do the data show? Seminars in perinatology 2006.
  3. Kagan KO, Avgidou K, Molina FS, Gajewska K, Nicolaides KH. Realation between increased fetal nuchal translucency thickness and chromosomal defects. Obstet Gynecol 2006; 107:6-10.
  4. Evans M I, O’Brien J E, Dvorin E, Harrison E, Bui T H. Second-trimester biochemical screening. Clin Perinatol.2001 Jun;28(2):289-301. Newberger DS. Down Syndrome: Prenatal risk assessment and diagnosis. American Academy of Family Physicians 2000; 15;62(4):825-32.
  5. Wald N J, Cuckle H. AFP and age screening for Down Syndrome. American Journal of Medical Genetics. 1988; 31(1):197– 209. ACOG Practice Bulletin No. 88, December 2007. Invasive prenatal testing for aneuploidy. Obstet Gynecol 2007; 110(6):1459-67.
  6. Jung V, Künzin HJ. Hemorrhagic shock caused by intraperitoneal hemorrhage after amniocentesis. Geburtshilfe Frauenheilkd. 1995;55(7):411-3.
  7. Dodgson J, Martin J, Boswell J, Goodall HB, Smith R. Probable amniotic fluid embolism precipitated by amniocentesis and treated by exchange transfusion. British Medical Journal 1987;294:1322-3.
  8. Hasaart TH, Essed GG. Amniotic fluid embolism after transabdomimal amniocentesis. Eur J Obstet Gynecol Biol 1983;16(1):25-30.
  9. Wurster KG, Roemer VM, Decker K, Hirsch HA. Amniotic infection syndrome after amniocentesis- a case report. Geburtshilfe Fraunheilkd 1982;42(9):676-9.
  10. Malone FD, Canick JA, Ball RH, Nyberg DA, Comstock CH, Bukowski R, et al. First- and Second-Trimester Evaluation of Risk (FASTER) Research Consortium. First-Trimester or Second-Trimester Screening or Both, for Down Syndrome. N Engl J Med 2005; 353(19):2001-11.
  11. Yaron Y, Cherry M, Kramer RL, et al. Secon-trimester maternal serum marker screening: Maternal serum a-fetoprotein, beta-human chorionic gonadotropin, estriol, and their various combinations as predictors of pregnancy outcome. Am J Obstet Gynecol 1999;181:968-974. Çınar K. Ayşegül. Fetal Kromozom Anomalisi Tarama Testleri. JOPP Dergi. 2010; 2(2):55-60 Sucu V,Yıldırmak S,Vardar M,Mihmanlı V. İkili ve Üçlü Tarama Testi Biyokimyasal Parametrelerinin Hastanemize Ait Medyanlarının Değerlendirilmesi. Abant Tıp Dergisi 2018; 7(2):35-40 Duran İ. Bingöl Bölgesinde Üçlü Tarama Testi Parametrelerinin Medyan Değerlerinin Belirlenmesi. Türk Klinik Biyokimya Dergisi 2017; 15(2): 37-44. Ayyıl