Journals / Middle Black Sea Journal of Health Science / 2021 / Cilt: 7 - Sayı: 1

Predictive Role of Large Unstained Cells (LUC) and Hematological Data in the Differential Diagnosis of Orchitis and Testicular Torsion

Pages
97–103
Publication Date
2021-04-30
DOI
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The highest area under curve values were found for LUC, LUC% and neutrophils, respectively, 0.752 (0.660-0.843), 0.698 (0.605-0.790), 0.383 (0.284-0.482).Conclusion: The results of this study showed that the LUC and LUC% values obtained from complete blood count (CBC) can be reliably used in the differential diagnosis of EO and TT

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The main aim of this retrospective evaluation of patients presenting with the complaint of acute scrotal pain was to investigate whether large unstained cells (LUC) in the hematological data, percentage of LUC, and the other haematological parameters would be of benefit in differential diagnosis.
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Key Findings & Data:Primarily the large unstained cell and other hematological data of the patients were evaluated.Results: Statistical differences were evaluated in LUC, LUC%, platelet, neutrophil, leucocyte, mean platelet volume, neutrophil / lymphocyte, platelet / lymphocyte values among the groups (p values respectively 0.001, ˂0.001, 0.491, ˂0.001, ˂0.001, 0.031, ˂0.001, 0.001).
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Conclusion & Impact:The highest area under curve values were found for LUC, LUC% and neutrophils, respectively, 0.752 (0.660-0.843), 0.698 (0.605-0.790), 0.383 (0.284-0.482).Conclusion: The results of this study showed that the LUC and LUC% values obtained from complete blood count (CBC) can be reliably used in the differential diagnosis of EO and TT
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:orchitis · large unstained cell(LUC) · testicular torsion

Abstract

Objective: The main aim of this retrospective evaluation of patients presenting with the complaint of acute scrotal pain was to investigate whether large unstained cells (LUC) in the hematological data, percentage of LUC, and the other haematological parameters would be of benefit in differential diagnosis. The secondary aim was to investigate the utility of LUC and LUC% as a new biochemical marker in the differential diagnosis of TT and EO.Methods: In this study, a retrospective evaluation was made of patients who presented with the complaint of acute scrotal pain at the emergency polyclinic. The patients were evaluated in three groups; testicular torsion, orchitis, and the control group. Primarily the large unstained cell and other hematological data of the patients were evaluated.Results: Statistical differences were evaluated in LUC, LUC%, platelet, neutrophil, leucocyte, mean platelet volume, neutrophil / lymphocyte, platelet / lymphocyte values among the groups (p values respectively 0.001, ˂0.001, 0.491, ˂0.001, ˂0.001, 0.031, ˂0.001, 0.001). The cutoff values for the differentiation of epididimo-orchitis (EO) were determined in the differential diagnosis of EO and TT. The highest area under curve values were found for LUC, LUC% and neutrophils, respectively, 0.752 (0.660-0.843), 0.698 (0.605-0.790), 0.383 (0.284-0.482).Conclusion: The results of this study showed that the LUC and LUC% values obtained from complete blood count (CBC) can be reliably used in the differential diagnosis of EO and TT

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Cite This Article

KESEROĞLU, B. B., GÜNGÖRER, B. (2021). Predictive Role of Large Unstained Cells (LUC) and Hematological Data in the Differential Diagnosis of Orchitis and Testicular Torsion. Middle Black Sea Journal of Health Science, Cilt: 7 - Sayı: 1, 97–103. https://ajindex.com/articles/791082

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References (14)

  1. Pogorelić Z, Mrklić I, Jurić I. Do not forget to include testicular torsion in differential diagnosis of lower acute abdominal pain in young males. J Pediatr Urol, 2013;9(6 PART B):1161–5
  2. Pogorelić Z, Mustapić K, Jukić M, Todorić J, Mrklić I, Meštrović J, et al. Management of acute scrotum in children: A 25-year single center experience on 558 pediatric patients. Can J Urol. 2016;23(6):8594–601
  3. Karakan T, Bagcyoglu M, Ozcan S, Telli O, Turgut H, Ozkan M, et al. Seasonal preponderance in testicular torsion: Is it a myth? Arch Esp Urol. 2015;68(10):750–4
  4. Mellick LB. Torsion of the Testicle. Pediatr Emerg Care. 2012;28(1):80–6
  5. Gunther P, Schenk JP, Wunsch R, Holland-Cunz S, Kessler U, Troger J, et al. Acute testicular torsion in children: The role of sonography in the diagnostic workup. Eur Radiol 2006;16(11):2527–32
  6. Bitkin A, Aydın M, Ozgur BC, Irkilata L, Akgunes E, Keles M, et al. Can haematologic parameters be used for differential diagnosis of testicular torsion and epididymitis? Andrologia. 2018;50(1):1–6
  7. Cicek T, Togan T, Akbaba K, Narci H, Aygun C. The value of serum mean platelet volume in testicular torsion. J Int Med Res.2015;43(3):452–9
  8. Meštrović J, Biočić M, Pogorelić Z, Furlan D, Družijanić N, Todorić D, et al. Differentiation of inflammatory from non-inflammatory causes of acute scrotum using relatively simple laboratory tests: Prospective study. J Pediatr Urol [Internet]. 2013;9(3):313–7
  9. Yamis S, Gedik A, Sahin H, Batun S, Nergiz Y, Bircan K. Is procalcitonin valuable in the differential diagnosis of testicular torsion and epididymo-orchitis. Saudi Med J. 2010;31(2):170–4
  10. Kartal O, Kartal AT. MPV: A reliable method to determine the prognosis? Vol. 37, Renal Failure. Informa Healthcare; 2015. p. 184
  11. Cakir I, Cakir N, Atalay MA, Koc AN. Large unstained cells are correlated with inflammatory biomarkers in patients with invasive aspergillosis. Turkish J Biochem. 2018;43(3):306–11
  12. Bononi A, Lanza F, Ferrari L, Gusella M, Gilli G, Abbasciano V, et al. Predictive value of hematological and phenotypical parameters on postchemotherapy leukocyte recovery. Cytom Part B - Clin Cytom. 2009;76(5):328–33
  13. Drewinko B, Bollinger P, Brailas C, Wyatt J, Simson E, Trujillo JM. Flow cytochemical patterns of white blood cells in human haematopoietic malignancies. II. Chronic leukaemias. Br J Haematol. 1987;67(2):157–65
  14. Vanker N, Ipp H. Large unstained cells: A potentially valuable parameter in the assessmen