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Journals / Journal of Health Sciences and Medicine / 2022 / Cilt: 5 - Sayı: 4

Effect of chitosan application on lung tissue in rats with experimental fluorine toxicity

Bahattin BULDUK
Pages
969–972
Publication Date
2022-07-20
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was found that the chitosan application reduced the CAT, SOD and GSH values, and increased the MDA value.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: The aim of this study is to investigate the effects of chitosan application on lung tissue in rats with experimental fluorine toxicity.
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Key Findings & Data:Material and Method: In the study, 21 healthy male wistar albino rats were used.
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Conclusion & Impact:It was found that the chitosan application reduced the CAT, SOD and GSH values, and increased the MDA value.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Chitosan · Sodium fluoride · Antioxidant

Abstract

Aim: The aim of this study is to investigate the effects of chitosan application on lung tissue in rats with experimental fluorine toxicity. Material and Method: In the study, 21 healthy male wistar albino rats were used. Prior to the trial, the acclimation of the rats was provided. 3 groups were randomly generated in a way that there were 7 rats in each group. These were determined as the control group (C), the fluorosis group (NaF) and the fluorosis + chitosan (NaF+CS) group. Results: In the NaF group, CAT, SOD and GSH values were found to be low compared to other groups and MDA values were found to be high. It was found that the chitosan application reduced the CAT, SOD and GSH values, and increased the MDA value. Conclusion: It has been predicted that chitosan application may be beneficial in preventing cellular damage that may occur with fluorine exposure.

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Cite This Article

BULDUK, B. (2022). Effect of chitosan application on lung tissue in rats with experimental fluorine toxicity. Journal of Health Sciences and Medicine, Cilt: 5 - Sayı: 4, 969–972. https://ajindex.com/articles/776492

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