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Journals / Balıkesir Sağlık Bilimleri Dergisi / 2020 / Cilt: 9 - Sayı: 2

The prognostic impact of dynamic change in neutrophil to lymphocyte ratio in patients with acute pulmonary embolism

Akut pulmoner emboli hastalarında nötrofil-lenfosit oranındaki dinamik değişimin prognostik etkisi

Adil GÖKUÇ
Tuncay KIRIŞ
Tarık YILDIRIM
Eyüp AVCI
Pages
101–108
Publication Date
2020-08-31
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: During follow-up, there were 30 deaths (14%). ΔNLR was higher in non-survivors than survivors survivors (5.22 [0.62-7.76] vs -0.71 [-2.28-0.76], P

📌 3 Key Takeaways

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Objective & Hypothesis:Background: It is unclear whether temporal changes in neutrophil to lymphocyte ratio (NLR) are associated with total mortality in acute pulmonary embolism (APE).
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Key Findings & Data:Methods: We retrospectively analyzed 214 consecutive APE patients.
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Conclusion & Impact:Results: During follow-up, there were 30 deaths (14%). ΔNLR was higher in non-survivors than survivors survivors (5.22 [0.62-7.76] vs -0.71 [-2.28-0.76], P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:nötrofil lenfosit oranı · inflamasyon · pulmoner emboli

Abstract

Background: It is unclear whether temporal changes in neutrophil to lymphocyte ratio (NLR) are associated with total mortality in acute pulmonary embolism (APE). We investigated the value of dynamic monitoring of NLR for the prognosis in patients with APE. Methods: We retrospectively analyzed 214 consecutive APE patients. The patients were divided into two groups: survivors or non-survivors. The neutrophil count, lymphocyte count and NLR were obtained at admission and 72 hours. The difference between the 2 measurements was considered as the NLR change (ΔNLR). The end point of the study was total mortality at 30-day follow-up. Results: During follow-up, there were 30 deaths (14%). ΔNLR was higher in non-survivors than survivors survivors (5.22 [0.62-7.76] vs -0.71 [-2.28-0.76], P

Özet

Amaç: Nötrofil / lenfosit oranındaki (NLO) zamansal değişikliklerin akut pulmoner embolide (APE) toplam mortalite ile ilişkili olup olmadığı açık değildir. APE'li hastalarda prognoz için NLO'nun dinamik izlenmesinin değerini araştırdık. Yöntemler: 214 ardışık APE hastasını geriye dönük olarak analiz ettik. Hastalar hayatta kalanlar veya hayatta kalmayanlar olarak iki gruba ayrıldı. Nötrofil sayısı, lenfosit sayısı ve NLO, başvuru sırasında ve 72. saatte elde edildi. İki ölçüm arasındaki fark NLR değişimi (ΔNLR) olarak kabul edildi. Çalışmanın sonlanım noktası, 30 günlük takipte toplam ölüm oranıydı. Bulgular: Takip sırasında 30 ölüm (% 14) saptandı. ΔNLR, hayatta kalmayanlarda hayatta kalanlara göre daha yüksekti (5.22 [0.62-7.76] ve -0.71 [-2.28-0.76], P

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Cite This Article

GÖKUÇ, A., KIRIŞ, T., YILDIRIM, T., AVCI, E. (2020). The prognostic impact of dynamic change in neutrophil to lymphocyte ratio in patients with acute pulmonary embolism. Balıkesir Sağlık Bilimleri Dergisi, Cilt: 9 - Sayı: 2, 101–108. https://ajindex.com/articles/739258

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References (2)

  1. Aujesky, D., Obrosky, D. S., Stone, R. A., Auble, T. E., Perrier, A., Cornuz, J., Roy, P. M., & Fine, M. J. (2005). Derivation and validation of a prognostic model for pulmonary embolism. American Journal of Respiratory and Critical Care Medicine, 172(8), 1041–1046. doi: 10.1164/rccm.200506-862OC Bakirci, E. M., Topcu, S., Kalkan, K., Tanboga, I. H., Borekci, A., Sevimli, S., & Acikel, M. (2015). The Role of the Nonspecific Inflammatory Markers in Determining the Anatomic Extent of Venous Thromboembolism. Clinical and Applied Thrombosis/Hemostasis, 21(2), 181–185. doi: 10.1177/1076029613494469 Başer, K., Duygu Baş, H., Attaluri, P., Rodrigues, T., Nichols, J., & Nugent, K. (2017). Changes in neutrophil-to-lymphocyte ratios in postcardiac arrest patients treated with targeted temperature management. Anatol J Cardiol, 18, 215–222. doi: 10.14744/AnatolJCardiol.2017.7716 Becattini, C. (2008). Predictors of mortality from pulmonary embolism and their influence on clinical management. Thromb. Haemost, 100, 747–751.
  2. Becattini, Cecilia, Vedovati, M. C., & Agnelli, G. (2007). Prognostic Value of Troponins in Acute Pulmonary Embolism A Meta-Analysis. doi: 10.1161/CIRCULATIONAHA.106.680421 Begieneman, M. P. V., Van De Goot, F. R. W., Van Der Bilt, I. A. C., Vonk Noordegraaf, A., Spreeuwenberg, M. D., Paulus, W. J., Van Hinsbergh, V. W. M., Visser, F. C., & Niessen, H. W. M. (2008). Pulmonary embolism causes endomyocarditis in the human heart. Heart, 94(4), 450–456. doi: 10.1136/hrt.2007.118638 Binder, L., Pieske, B., Olschewski, M., Geibel, A., Klostermann, B., Reiner, C., & Konstantinides, S. (2005). N-terminal pro-brain natriuretic peptide or troponin testing followed by echocardiography for risk stratification of acute pulmonary embolism. Circulation, 112(11), 1573–1579. doi: 10.1161/CIRCULATIONAHA.105.552216 Gallotta, G., Palmieri, V., Piedimonte, V., Rendina, D., De Bonis, S., Russo, V., Celentano, A., Di Minno, M. N. D., Postiglione, A., & Di Minno, G. (2008). Increased troponin I predicts in-hospital occurrence of hemodynamic instability in patients with sub-massive or non-massive pulmonary embolism independent to clinical, echocardiographic and laboratory information. International Journal of Cardiology, 124(3), 351–357. doi: 10.1016/j.ijcard.2006.03.096 Goldhaber, S. Z., Visani, L., & De Rosa, M. (1999). Acute pulmonary embolism: Clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER). Lancet, 353(9162), 1386–1389. doi: 10.101