Journals / ADO Klinik Bilimler Dergisi / 2013 / Cilt: 6 - Sayı: 4

Mandibular Central Giant Cell Granuloma Associated with Secondary Hyperparathyroidism

Mandibulada Sekonder Hiperparatiroidizmle İlişkili Santral Dev Hücreli Granüloma

Pages
1365–1369
Publication Date
2013-01-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this report; we report a 50-year-old female patient with mandibular central giant cell granuloma as a first sign of secondary hyperthyroidism induced due to vitamin D deficiency and hypocalcemia

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 50 years old female patient was referred to our clinic with the complaint of painless swelling of the mandibular anterior region.
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Key Findings & Data:Blood tests demonstrated elevations in parathyroid hormone PTH concentrations and low level of vitamin D.
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Conclusion & Impact:In this report; we report a 50-year-old female patient with mandibular central giant cell granuloma as a first sign of secondary hyperthyroidism induced due to vitamin D deficiency and hypocalcemia
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hiperparatiroidizm · D vitamini eksikliği · Santral Dev Hücreli Granüloma

Abstract

A 50 years old female patient was referred to our clinic with the complaint of painless swelling of the mandibular anterior region. The intraoral examination revealed a painless hardened mass fixed to deeper layers in the anterior mandibular region. Panoramic radiograph that was made at her previous visit of another hospital was examined and cone beam computed tomograpy imaging was performed. After the diagnosis was confirmed with incisional biopsy, the lesion was completely excised. Cone beam computed tomography imaging revealed a radiolucent bone lesion presenting thin septa with well-defined radiopaque scalloped borders in the anterior mandible. Histopathological examination revealed central giant cell granuloma. Blood tests demonstrated elevations in parathyroid hormone PTH concentrations and low level of vitamin D. Central giant cell granuloma affects mostly adolescents and young adults. In this report; we report a 50-year-old female patient with mandibular central giant cell granuloma as a first sign of secondary hyperthyroidism induced due to vitamin D deficiency and hypocalcemia

Özet

Kliniğimize 50 yaşında kadın hasta mandibular anterior bölgede ağrısız şişlik şikayetiyle başvurdu. İntraoral muayenede mandibula anterior bölgede derin dokulara fikse, sert, ağrısız kitle tespit edildi. Hastanın başka bir merkezde çekilen panoramik radyografı incelendi ve konik ışınlı bilgisayarlı tomografi alındı. Konik ışınlı bilgisayarlı tomografide mandibula anterior bölgede düzgün, radyopak bir sınırla çevrili, kemik septası içeren, radyolüsent lezyon izlendi. İnsizyonel biyopsi ile tanı koyulduktan sonra lezyon tamamen çıkartıldı. Histopatolojik olarak santral dev hücreli granüloma tanısı koyuldu. Kan testleri parathormon seviyesinin yüksek, vitamin D seviyesinin düşük olduğunu gösterdi. Santral dev hücreli granüloma genellikle adolesanlarda ve genç yetişkinlerde görülür. Bu raporda 50 yaşındaki hastada santral dev hücreli granüloma olgusu, vitamin D eksikliği ve hipokalsemi nedeniyle gelişen sekonder hiperparatiroidizmin ilk bulgusu olarak sunulmuştur

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Cite This Article

YILDIRIM, D., BİLGİR, E., FINDIK, Y. (2013). Mandibular Central Giant Cell Granuloma Associated with Secondary Hyperparathyroidism. ADO Klinik Bilimler Dergisi, Cilt: 6 - Sayı: 4, 1365–1369. https://ajindex.com/articles/728835

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