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Journals / ADO Klinik Bilimler Dergisi / 2026 / Cilt: 15 Sayı: 3

Effect of Low-Concentration Chlorhexidine Mouthrinses on the Microleakage of Class V Resin Composite Restorations: An In Vitro Study

Düşük Konsantrasyonlu Klorheksidin İçeren Ağız Gargaralarının Sınıf V Rezin Kompozit Restorasyonlarda Mikrosızıntı Üzerine Etkisi: İn Vitro Bir Çalışma

Ece Açıkgöz Alparslan(TRAKYA ÜNİVERSİTESİ, DİŞ HEKİMLİĞİ FAKÜLTESİ)0000-0003-4560-6156
Mediha Büyükgöze Dindar(TRAKYA ÜNİVERSİTESİ, DİŞ HEKİMLİĞİ FAKÜLTESİ)0000-0003-3794-4366
Pages
211–221
Publication Date
2026-09-25
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Within the limitations of this study, prolonged exposure to low-concentration CHX-containing mouthrinses may compromise the marginal integrity of Class V resin composite restorations.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: This in vitro study investigated the effect of two daily-use mouthrinses containing 0.05% chlorhexidine (CHX), with or without cetylpyridinium chloride (CPC), on the microleakage of standardized Class V resin composite restorations.
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Key Findings & Data:After finishing, polishing, and thermocycling (1000 cycles, 5–55 °C), specimens were randomly assigned to three groups (n = 15): artificial saliva (control), CHX-only mouthrinse, and CHX + CPC mouthrinse.
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Conclusion & Impact:Conclusion: Within the limitations of this study, prolonged exposure to low-concentration CHX-containing mouthrinses may compromise the marginal integrity of Class V resin composite restorations.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Gargaralar · Klorheksidin glukonat · Dental sızıntı

Abstract

Objective: This in vitro study investigated the effect of two daily-use mouthrinses containing 0.05% chlorhexidine (CHX), with or without cetylpyridinium chloride (CPC), on the microleakage of standardized Class V resin composite restorations. Materials and Methods: Forty-five sound human premolars were included. Standardized non-beveled Class V cavities were prepared on the buccal surfaces and restored using a universal adhesive system and resin composite. After finishing, polishing, and thermocycling (1000 cycles, 5–55 °C), specimens were randomly assigned to three groups (n = 15): artificial saliva (control), CHX-only mouthrinse, and CHX + CPC mouthrinse. To simulate cumulative exposure equivalent to one year of daily use, each specimen was immersed in the assigned solution for 12 h. After methylene blue dye immersion and buccolingual sectioning, microleakage was assessed by stereomicroscopic examination at 40× magnification using an ordinal scoring system. A p-value of < 0.05 was considered statistically significant. Results: Mean microleakage scores were 1.80 ± 0.46 in the control group, 2.80 ± 0.65 in the CHX group, and 2.77 ± 0.62 in the CHX + CPC group. A statistically significant difference was observed among the groups (p < 0.001). Both CHX-containing mouthrinse groups showed significantly higher microleakage than the control group (p < 0.001), whereas no significant difference was found between the CHX and CHX + CPC groups (p = 0.870). Conclusion: Within the limitations of this study, prolonged exposure to low-concentration CHX-containing mouthrinses may compromise the marginal integrity of Class V resin composite restorations.

Özet

Amaç: Bu in vitro araştırmada, %0,05 klorheksidin (CHX) içeren ve setilpiridinyum klorür (CPC) içeriğine göre farklılık gösteren iki günlük kullanım ağız gargarasının standardize edilmiş Sınıf V rezin kompozit restorasyonlarda mikrosızıntı üzerindeki etkisi incelenmiştir. Gereç ve Yöntem: Çalışmada 45 sağlıklı insan premoları kullanıldı. Bukkal yüzeylere standart, bevelsiz Sınıf V kaviteler hazırlanarak üniversal adeziv sistem ve rezin kompozit ile restore edildi. Bitim ve polisajın ardından örnekler termal siklusa (1000 siklus, 5–55 °C) tabi tutuldu ve yapay tükürük (kontrol), yalnızca CHX içeren gargara ve CHX + CPC içeren gargara olmak üzere rastgele üç gruba ayrıldı (n = 15). Bir yıllık günlük kullanım eşdeğerini simüle etmek amacıyla her örnek ilgili solüsyonda 12 saat tutuldu. Metilen mavisi ile boyama ve bukkolingual yönde kesit alma işlemlerinin ardından, mikrosızıntı 40× büyütmede stereomikroskobik inceleme ile ordinal bir skor sistemi kullanılarak değerlendirildi. p < 0,05 istatistiksel olarak anlamlı kabul edildi. Bulgular: Ortalama mikrosızıntı skorları kontrol grubunda 1.80 ± 0.46, CHX grubunda 2.80 ± 0.65 ve CHX + CPC grubunda 2.77 ± 0.62 idi. Gruplar arasında istatistiksel olarak anlamlı fark gözlendi (p < 0.001). CHX içeren her iki gargara grubu, kontrol grubuna göre anlamlı olarak daha yüksek mikrosızıntı gösterdi (p < 0.001); buna karşın CHX ve CHX + CPC grupları arasında anlamlı fark bulunmadı (p = 0.870). Sonuç: Bu çalışmanın sınırlılıkları dahilinde, düşük konsantrasyonlu CHX içeren ağız gargaralarına uzun süreli maruziyet Sınıf V rezin kompozit restorasyonların marjinal bütünlüğünü etkileyebilir.

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Cite This Article

Alparslan, E. A., Dindar, M. B. (2026). Effect of Low-Concentration Chlorhexidine Mouthrinses on the Microleakage of Class V Resin Composite Restorations: An In Vitro Study. ADO Klinik Bilimler Dergisi, Cilt: 15 Sayı: 3, 211–221. https://doi.org/10.54617/adoklinikbilimler.1914912

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