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Journals / ADO Klinik Bilimler Dergisi / 2022 / Cilt: 11 - Sayı: 3

Evaluation of salivary visfatin, leptin and oxidative stress markers in obese and non-obese periodontitis patients.

Obez olan ve olmayan periodontitis hastalarında tükürük visfatin, leptin ve oksidatif stres belirteçlerinin değerlendirilmesi.

Seval CEYLAN ŞEN
Erkan ÖZCAN
Nuriye SAYGUN
Taner ÖZGÜRTAŞ
Rashad AZIZOV
Pages
270–279
Publication Date
2022-09-19
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: It was determined that leptin and TAOC levels were higher in periodontal healthy groups than in the periodontitis groups; visfatin, NO and TOC levels were higher in periodontitis groups than periodontally healthy groups(P

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: The aim of this study is to evaluate leptin, visfatin, nitric oxide(NO), total oxidant capacity(TOC) and antioxidant capacity(TAOC) levels in saliva at obese and non-obese periodontitis patients.
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Key Findings & Data:Materials and Methods: Total of 78 individuals were included in study, 20 obese periodontal healthy(Group I), 18 obese periodontitis(Group II), 20 non-obese periodontal healthy(Group III) and 20 non-obese periodontitis(Group IV).
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Conclusion & Impact:Results: It was determined that leptin and TAOC levels were higher in periodontal healthy groups than in the periodontitis groups; visfatin, NO and TOC levels were higher in periodontitis groups than periodontally healthy groups(P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:leptin · obezite · oksidatif stres

Abstract

Objectives: The aim of this study is to evaluate leptin, visfatin, nitric oxide(NO), total oxidant capacity(TOC) and antioxidant capacity(TAOC) levels in saliva at obese and non-obese periodontitis patients. Materials and Methods: Total of 78 individuals were included in study, 20 obese periodontal healthy(Group I), 18 obese periodontitis(Group II), 20 non-obese periodontal healthy(Group III) and 20 non-obese periodontitis(Group IV). Periodontal clinical parameters, body mass index(BMI) and waist circumference measurements were recorded.ELISA and Griess methods were used for biochemical analysis of saliva. Results: It was determined that leptin and TAOC levels were higher in periodontal healthy groups than in the periodontitis groups; visfatin, NO and TOC levels were higher in periodontitis groups than periodontally healthy groups(P

Özet

Amaç: Bu çalışmanın amacı obez olan ve olmayan periodontitis hastalarında tükürükte leptin, visfatin, nitrik oksit (NO),total oksidan kapasite (TOK) ve total antioksidan kapasite (TAOK) düzeylerini değerlendirmektir. Gereç ve Yöntem: Çalışmaya 20 obez periodontal sağlıklı (Grup I), 18 obez periodontitis (Grup II), 20 obez olmayan periodontal sağlıklı (Grup III) ve 20 obez olmayan periodontitis (Grup IV) olmak üzere toplam 78 birey dahil edildi. Periodontal klinik parametreler, vücut kitle indeksi (VKİ) ve bel çevresi ölçümleri kaydedildi. Tükürüğün biyokimyasal analizi için ELISA ve Griess yöntemleri kullanıldı. Bulgular: Leptin ve TAOC düzeylerinin periodontal sağlıklı gruplarda (Grup I ve Grup III) periodontitis gruplarına (Grup II ve Grup IV) göre daha yüksek olduğu; visfatin, NO ve TOC düzeylerinin de periodontitis gruplarında periodontal olarak sağlıklı gruplara göre daha yüksek olduğu saptandı (P

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Cite This Article

ŞEN, S. C., ÖZCAN, E., SAYGUN, N., ÖZGÜRTAŞ, T., AZIZOV, R. (2022). Evaluation of salivary visfatin, leptin and oxidative stress markers in obese and non-obese periodontitis patients.. ADO Klinik Bilimler Dergisi, Cilt: 11 - Sayı: 3, 270–279. https://ajindex.com/articles/728782

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