The Relationship Between Procalcitonin Levels and Coronary Slow Flow.

Key Findings & Data:We aimed to evaluate the relationship between procalcitonin and coronary slow flow phenomenon.Material and Method: The present study included 50 patients with coronary slow flow and 42 healthy subjects.

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Conclusion & Impact:We have shown the relationship between serum C-reactive protein and coronary slow flow.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:koroner yavaş akım · prokalsitonin · CRP

Abstract

Objective: Coronary slow flow phenomenon is associated with angina pectoris and acute coronary syndromes. Procalcitonin levels are correlated with the extent of atherosclerosis in patients with coronary artery disease. We aimed to evaluate the relationship between procalcitonin and coronary slow flow phenomenon.Material and Method: The present study included 50 patients with coronary slow flow and 42 healthy subjects. The coronary slow flow phenomenon is defined as delayed coronary opacification in the absence of obstructive coronary artery disease. Coronary slow flow is evaluated with Thrombolysis in Myocardial Infarction frame count method. The Procalcitonin was calculated from the blood to analyze. Results: The C-reactive protein was significantly higher in the coronary slow flow group than the control group. There was a positive and significant correlation between the Mean Thrombolysis in Myocardial Infarction frame count and CRP levels. There were no correlations between the C-reactive protein and procalcitonin levels (r= -0.134, p= 0.204). Conclusion: Serum procalcitonin level was not associated with coronary slow flow. We have shown the relationship between serum C-reactive protein and coronary slow flow.

Özet

Amaç: Koroner yavaş akım fenomeni anjina pektoris ve akut koroner sendrom ile ilişkilidir. Prokalsitonin seviyeleri koroner arter hastalığı olan hastalarda aterosklerozun yaygınlığı ile ilişkilidir. Bu çalışmada prokalsitonin ve koroner yavaş akım fenomeni arasındaki ilişkinin değerlendirilmesi amaçladık. Yöntem: Çalışmaya koroner yavaş akımı olan 50 hasta ve 42 sağlıklı birey alındı. Koroner yavaş akım fenomeni, obstrüktif koroner arter hastalığı yokluğunda gecikmiş koroner opasifikasyon olarak tanımlanmaktadır. Koroner yavaş akım, Tromboliz Miyokard İnfarktüsü frame sayma yöntemi ile değerlendirildi. Prokalsitonin değerleri kandan analiz edildi. Bulgular: C-reaktif protein koroner yavaş akım grubunda kontrol grubundan anlamlı derecede yüksekti. Ortalama Tromboliz Miyokard İnfarktüsü frame sayıs ile CRP düzeyleri arasında pozitif ve anlamlı bir korelasyon vardı. C-reaktif protein ve prokalsitonin düzeyleri arasında korelasyon yoktu (r = -0.134, p = 0.204). Sonuç: Serum prokalsitonin düzeyi koroner yavaş akım ile ilişkili değildi. Bu çalışmada serum C-reaktif protein ve koroner yavaş akım arasındaki ilişkiyi gösterdik.

Keywords

koroner yavaş akım prokalsitonin CRP coronary slow flow procalcitonin

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Cite This Article

Asoğlu, R., Kaya, H., Asoğlu, E., Afşin, A., Süner, A. (2019). The Relationship Between Procalcitonin Levels and Coronary Slow Flow.. Adıyaman Üniversitesi Sağlık Bilimleri Dergisi, Cilt: 5 - Sayı: 2, 1528–1539. https://ajindex.com/articles/728059

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References (15)

Tambe AA, Demany MA, Zimmerman HA, et al. Angina pectoris and slow flow velocity of dye in coronary arteries--a new angiographic finding. Am Heart J. 1972 Jul;84(1):66–71
Sezgin AT, Sgrc A, Barutcu I, et al. Vascular endothelial function in patients with slow coronary flow. Coron Artery Dis. 2003;14(2):155–161
Pekdemir H, Cin VG, Çiçek D, et al. Slow coronary flow may be a sign of diffuse atherosclerosis. Contribution of FFR and IVUS. Acta Cardiol. 2004;59(2):127–33
Horjeti B, Goda A. Acute ischemia manifestation in a patient with coronary slow flow phenomenon. J Electrocardiol. 2012;45(3):277–9
Wożakowska-Kapłon B, Niedziela J, Krzyżak P, et al. Clinical manifestations of slow coronary flow from acute coronary syndrome to serious arrhythmias. Cardiol J. 2009;16(5):462–8
Kalay N, Aytekin M, Kaya MG, et al. The relationship between inflammation and slow coronary flow: increased red cell distribution width and serum uric acid levels. Arch Turk Soc Cardiol. 2011;39(6):463–8
Ross R. 011499 Atherosclerosis -- An Inflammatory Disease. N Engl J Med. 1999;12
Haverkate E, Thompson SG, Pyke SD, et al. Production of C-reactive protein and risk of coronary events in stable and unstable angina. The Lancet. 1997 Feb 15;349(9050):462–6
Assicot M, Bohuon C, Gendrel D, et al. High serum procalcitonin concentrations in patients with sepsis and infection. The Lancet. 1993 Feb 27;341(8844):515–8
Whicher J, Bienvenu J, Monneret G. Procalcitonin as an Acute Phase Marker. Ann Clin Biochem.:11
Kafkas N, Venetsanou K, Patsilinakos S, et al. Procalcitonin in acute myocardial infarction. Acute Card Care. 2008 Jan 1;10(1):30–6
Ataoğlu H, Yilmaz F, Uzunhasan I, et al. Procalcitonin: A Novel Cardiac Marker with Prognostic Value in Acute Coronary Syndrome. J Int Med Res. 2010 Feb;38(1):52–61
Gibson CM, Cannon CP, Daley WL, et al. TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation. 1996 Mar 1;93(5):879–88. 14. de Werra I, Jaccard C, Corradin SB, et al. Cytokines, nitrite/nitrate, soluble tumor necrosis factor receptors, and procalcitonin concentrations: Comparisons in patients with septic shock, cardiogenic shock, and bacterial pneumonia. Crit Care Med. 1997 Apr;25(4):607
Buratti T, Ricevuti G, Pechlaner C, et al. Plasma Levels of Procalcitonin and Interleukin-6 in Acute Myocardial Infarction. Inflammation. 2001 Apr 1;25(2):97–100
Ilhan F, Akbulut H, Karaca I, et al. Procalcitonin, c-rea