Journals / Gazi Mühendislik Bilimleri Dergisi / 2018 / Cilt: 4 - Sayı: 3

Investigation of Candida Microorganisms Adherence to Polymeric Surfaces: A Review

Candida Mikroorganizmalarının Polimerik Yüzeylere Yapışmasının İncelenmesi

Pages
157–167
Publication Date
2018-12-24
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The aim of this study is the investigation of relationship between surface properties of polymeric materials and adhesion of Candida microorganisms who known as opportunist pathogens in medical area and the main reason of the systemic fungal infections.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Microorganism adhesion on a material surface plays a crucial role on the application of biomedical devices, implants, drug delivery systems, scaffolds and so on.
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Key Findings & Data:Desirable surfaces which have bioactive, bioinert or anti-biofoul property can be prepared by physical adsorption of specific compounds on these surfaces or chemical modification.
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Conclusion & Impact:The aim of this study is the investigation of relationship between surface properties of polymeric materials and adhesion of Candida microorganisms who known as opportunist pathogens in medical area and the main reason of the systemic fungal infections.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Polimer Yüzeyler · Candida · Biyofilm

Abstract

Microorganism adhesion on a material surface plays a crucial role on the application of biomedical devices, implants, drug delivery systems, scaffolds and so on. Desirable surfaces which have bioactive, bioinert or anti-biofoul property can be prepared by physical adsorption of specific compounds on these surfaces or chemical modification. Micro/nano patterned surface fabrication is one of the most important ways of surface modification. Studies reveal that surface properties such as wettability (hydrophilicity/hydrophobicity) character of a surface, surface charge, surface free energy, and surface roughness effects the adhesion of the microorganisms on material surfaces. The aim of this study is the investigation of relationship between surface properties of polymeric materials and adhesion of Candida microorganisms who known as opportunist pathogens in medical area and the main reason of the systemic fungal infections.

Özet

Bir malzeme yüzeyi üzerindeki mikroorganizma adezyonu biyomedikal cihazlar, implantlar, ilaç salım sistemleri, yapı iskeleleri v.b. uygulamalarda kritik önem taşır. Biyoaktif, biyoinert, biyolojik kirlenmeyi önleyici özelliklere sahip olması istenen yüzeyler, spesifik bileşiklerin bu yüzeyler üzerine fiziksel adsorpsiyonu ya da kimyasal modifikasyon ile hazırlanabilirler. Mikro/nano desenli yüzey üretimi yüzey modifikasyon yollarının en önemli olanlarından biridir. Çalışmalar ıslatılabilirlik (hidrofilisite/hidrofobisite), bir yüzeyin karakteri, yüzey yükü, serbest yüzey enerjisi ve yüzey pürüzlülüğü gibi yüzey özelliklerinin malzeme yüzeylerine olan mikroorganizma adezyonunu etkilediğini ortaya koymaktadır. Bu çalışmanın amacı polimerik materyallerin yüzey özellikleri ile medikal alanda fırsatçı patojenler olarakta bilinen ve sistemik mantar enfeksiyonlarının başlıca sebebi olan Candida mikroorganizmalarının adezyonu arasındaki ilişkiyi incelemektir.

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Cite This Article

KIR, H., UÇAR, İ. O., KILINÇEL, Ö., ÇALIŞKAN, E. (2018). Investigation of Candida Microorganisms Adherence to Polymeric Surfaces: A Review. Gazi Mühendislik Bilimleri Dergisi, Cilt: 4 - Sayı: 3, 157–167. https://ajindex.com/articles/666761

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