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Journals / Turkish Journal of Urology / 2018 / Cilt: 44 - Sayı: 3

Do body mass index, hormone profile and testicular volume effect sperm retrieval rates of microsurgical sperm extraction in the patients with nonobstructive azoospermia?

Nonobstrüktif azoospermisi olan hastalarda vücut kitle indeksi, hormon profili ve testis hacmi, mikrocerrahi sperm ekstraksiyonunda sperm elde etme oranlarını etkiler mi?

Fuat KIZILAY
Serkan KARAMAZAK
Tuncer BAHÇECİ
Bülent SEMERCİ
Pages
202–207
Publication Date
2022-11-05
DOI
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The overall data were processed statistically with chi-square and logistic regression analysisand the relation between preoperative findings and sperm retrieval rates was investigated.Results: The sperm retrieval rate of 282 patients after microTESE was found as 41.1%.

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Objective & Hypothesis:Objective: We aimed to evaluate the effect of body mass index (BMI), follicle stimulating hormone (FSH),and luteinizing hormone (LH) levels and the mean testicular volume on sperm retrieval rates in microsurgicalsperm extraction (microTESE) in the patients with nonobstructive azoospermia (NOA).Material and methods: The data of 282 infertile patients with NOA were analysed retrospectively.
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Key Findings & Data:The overall data were processed statistically with chi-square and logistic regression analysisand the relation between preoperative findings and sperm retrieval rates was investigated.Results: The sperm retrieval rate of 282 patients after microTESE was found as 41.1%.
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Conclusion & Impact:FSHand LH levels and the mean testicular volume and pathologic findings were significantly correlated withsperm retrieval rates.Conclusion: Finally significant correlation was determined between sperm retrieval rates and FSH, and LHlevels and testicular volumes but no statistically significant difference was found in sperm retrieval ratesamong BMI groups
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: We aimed to evaluate the effect of body mass index (BMI), follicle stimulating hormone (FSH),and luteinizing hormone (LH) levels and the mean testicular volume on sperm retrieval rates in microsurgicalsperm extraction (microTESE) in the patients with nonobstructive azoospermia (NOA).Material and methods: The data of 282 infertile patients with NOA were analysed retrospectively. Thepatients with normal karyotype and no Y microdeletions were included in the study. The patients were classifiedaccording to their BMI scores and the medical history, physical examination and hormonal parameterswere evaluated. The overall data were processed statistically with chi-square and logistic regression analysisand the relation between preoperative findings and sperm retrieval rates was investigated.Results: The sperm retrieval rate of 282 patients after microTESE was found as 41.1%. There was no statisticallysignificant difference in sperm retrieval rates among the subgroups classified according to BMI. FSHand LH levels and the mean testicular volume and pathologic findings were significantly correlated withsperm retrieval rates.Conclusion: Finally significant correlation was determined between sperm retrieval rates and FSH, and LHlevels and testicular volumes but no statistically significant difference was found in sperm retrieval ratesamong BMI groups

Özet

Amaç: Çalışmamızda, nonobstrüktif azoospermi (NOA) olan hastalarda mikrocerrahi sperm ekstraksiyonunda (MikroTESE) vücut kitle indeksi (VKİ), follikül stimüle edici hormon (FSH), luteinize edici hormon (LH) seviyeleri ve ortalama testis hacimlerinin sperm elde edilmesine etkisini değerlendirmek amaçlandı. Gereç ve yöntemler: NOA olan 282 infertil hastanın verileri retrospektif olarak incelendi. Normal karyotipi olan ve Y mikrodelesyonu olmayan hastalar çalışmaya dahil edildi. Hastalar VKİ skorlarına göre sınıflandırıldı ve tıbbi öykü, fizik muayene ve hormonal parametreler değerlendirildi. Veriler, ki kare ve lojistik regresyon analizi ile istatistiksel olarak değerlendirildi ve ameliyat öncesi bulgular ile sperm elde edilmesi arasındaki ilişki araştırıldı. Bulgular: MikroTESE sonrası 282 hastanın sperm elde etme oranı %41,1 bulundu. VKİ’ye göre sınıflandırılan alt gruplar arasında sperm elde edilmesi oranlarında istatistiksel olarak anlamlı fark yoktu. FSH ve LH düzeyleri, ortalama testis hacmi ve patolojik bulgular ile sperm elde edilmesi oranları arasında anlamlı korelasyon bulundu. Sonuç: Sperm elde edilmesi oranları ile FSH, LH ve testis hacimleri arasında anlamlı bir ilişki saptanmış ancak VKİ grupları arasında sperm elde edilmesi oranlarında istatistiksel olarak anlamlı fark bulunamamıştır

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Cite This Article

KIZILAY, F., KARAMAZAK, S., BAHÇECİ, T., SEMERCİ, B. (2022). Do body mass index, hormone profile and testicular volume effect sperm retrieval rates of microsurgical sperm extraction in the patients with nonobstructive azoospermia?. Turkish Journal of Urology, Cilt: 44 - Sayı: 3, 202–207. https://ajindex.com/articles/654596

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References (5)

  1. Bonarriba CR, Burgues JP, Vidana V, Ruiz X, Piza P. Predictive factors of successful sperm retrieval in azoospermia. Actas Urol Esp 2013;37:266-72.[CrossRef] Seo JT, Ko WJ. Predictive factors of successful testicular sperm recovery in non-obstructive azoospermia patients. Int J Androl 2001;24:306-10. [CrossRef] Ramasamy R, Bryson C, Reifsnyder JE, Neri Q, Palermo GD, Schlegel PN. Overweight men with nonobstructive azoospermia have worse pregnancy outcomes after microdissection testicular sperm extraction. Fertil Steril 2013;99:372-6. [CrossRef] Taha EA, Sayed SK, Gaber HD, Hafez HKA, Ghandour N, Zahran A, et al. Does being overweight affect seminal variables in fertile men? Reprod Biomed Online 2016;33:703-8.
  2. Wu Z, Lu X, Wang M, Cheng H. Correlation between body mass index of Chinese males and assisted reproductive technology outcome. Int J Clin Exp Med 2015;8:21472-6.
  3. Macdonald AA, Stewart AW, Farquhar CM. Body mass index in relation to semen quality and reproductive hormones in New Zealand men: a cross-sectional study in fertility clinics. Hum Reprod 2013;28:3178-87. [CrossRef] Eisenberg ML, Kim S, Chen Z, Sundaram R, Schisterman EF, Louis GMB. The relationship between male BMI and waist circumference on semen quality: data from the LIFE study. Hum Reprod 2014;29:193-200. [CrossRef] MacDonald AA, Herbison GP, Showell M, Farquhar CM. The impact of body mass index on semen parameters and reproductive hormones in human males: a systematic review with meta-analysis. Hum Reprod Update 2010;16:293-311. [CrossRef] Nguyen RH, Wilcox AJ, Skjaerven R, Baird DD. Men’s body mass index and infertility. Hum Reprod 2007;22:2488-93. [CrossRef] Ziaee SA, Ezzatnegad M, Nowroozi M, Jamshidian H, Abdi H, Hosseini Moghaddam SM. Prediction of successful sperm retrieval in patients with nonobstructive azoospermia. Urol J 2006;3:92-6.
  4. Tsujimura A, Matsumiya K, Miyagawa Y, Takao T, Fujita K, Koga M, et al. Prediction of successful outcome of microdissection testicular sperm extraction in men with idiopathic nonobstructive azoospermia. J Urol 2004;172:1944-7. [CrossRef] Stokes VJ, Anderson RA, George JT. How does obesity affect fertility in men–and what are the treatment options? Clin Endocrinol (Oxf) 2015;82:633-8.
  5. Davidson LM, Millar K, Jones C, Fatum M, Coward K. Deleterious effects of obesity upon the hormonal and molecular mechanisms controlling spermatogenesis and male fertility. Hum Fertil (Camb) 2015;18:184-93. [CrossRef] Kolb BA, Stanczyk FZ, Sokol RZ. Serum inhibin B le