Journals / Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2009 / Cilt: 49 - Sayı: 3

Multiple xanthomas affecting quality of life: Case report

Yaşam kalitesini etkileyen multipl ksantom: Olgu sunumu

Pages
210–212
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Medical treatment and dietary therapy reduce postoperative recurrence rates and the other systemic complication risks.

📌 3 Key Takeaways

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Objective & Hypothesis:Xanthomas occur due to the accumulation of macrophages (foam cells) containing cholesterol esters and usually seen in hiperlipidaemic people.
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Key Findings & Data:Cholesterol accumulation causes edema and inflammation and this condition may cause pain, pruritus and the lesions under skin can cause cosmetic and functional complaints.
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Conclusion & Impact:Medical treatment and dietary therapy reduce postoperative recurrence rates and the other systemic complication risks.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Xanthomas occur due to the accumulation of macrophages (foam cells) containing cholesterol esters and usually seen in hiperlipidaemic people. Cholesterol accumulation causes edema and inflammation and this condition may cause pain, pruritus and the lesions under skin can cause cosmetic and functional complaints. Usually they located on hips, shoulders, extensor surface of the extremities as yellow pigmented papules. Xanthomas can be excised surgically, however may recur after surgery if not medicated with hypolipidemic drugs and dietary therapy. Medical treatment and dietary therapy reduce postoperative recurrence rates and the other systemic complication risks.

Özet

Ksantomlar kolesterol esterleri içeren makrofajların (köpük hücreleri) ciltte birikmesiyle oluşur ve genellikle hiperlipidemiyle beraber görülürler. Kolesterol esterleri ile yüklü hücreler biriktiği bölgede ödem ve enflamasyon meydana getirirler. Doku ödemi ve enflamasyon ağrı ve kaşıntıya neden olur, cilt altındaki kitleler ise kozmetik ve fonksiyonel bozukluğa yol açabilir. Sıklıkla kalçalarda, omuzlarda, ekstremitelerin ekstansör yüzeylerinde çeşitli büyüklükte sarı papüller olarak ortaya çıkarlar. Ksantomlar cerrahi eksizyon ile tedavi edilebilirler, ancak yüksek lipid düzeylerinin kontrol altına alıcı tedavi uygulanmadığı sürece yen ksantom oluşumu engellenemez. Hiperlipideminin medikal tedavisi ve hipolipidemik diet uygulamalar postoperatif nüks riskini azaltırken, diğer sistemik komplikasyonların da oluşmasını engeller.

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Cite This Article

UZUNİSMAİL, A., BAŞKURT, H., AYDIN, E. E., ZEYTİN, K., MORKOÇ, O. (2022). Multiple xanthomas affecting quality of life: Case report. Haydarpaşa Numune Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 49 - Sayı: 3, 210–212. https://ajindex.com/articles/651387

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References (5)

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