AI Summary & Key Takeaways
AI InsightIn this case report, a patient with Job’ssyndrome who presented with recurrent lung infections for the last 10 years, cough for 2 months, weight loss and lytic lesions in thevertebrae and was found to have spondylodiscitis due to methicillin-resistant S. aureus (MRSA) is discussed in the light of literature.
📌 3 Key Takeaways
Abstract
Autosomal dominant hyperimmunoglobulin E syndrome, Job’s syndrome, is a multisystemic immunodeficiency syndrome with recur rent staphylococcal and fungal infections, pneumonia, lymphadenitis, eczema, characteristic facial appearance, skeletal anomaliesthat occur early in life. Staphylococcus aureus is the most frequently isolated microorganism. In this case report, a patient with Job’ssyndrome who presented with recurrent lung infections for the last 10 years, cough for 2 months, weight loss and lytic lesions in thevertebrae and was found to have spondylodiscitis due to methicillin-resistant S. aureus (MRSA) is discussed in the light of literature.
Özet
Otozomal dominant hiperimmünglobulin E sendromu (Job’s sendromu); hayatın erken dönemlerinde ortaya çıkan, tekrarlayan stafi lokokal ve fungal infeksiyonlar, pnömoni, lenfadenit, egzama, karakteristik yüz görünümü, iskelet anomalileri görülen multisistemikbir immün yetmezlik sendromudur. Staphylococcus aureus en sık izole edilen mikroorganizmadır. Bu olgu sunumunda son 10 yıldırtekrarlayan akciğer infeksiyonları, 2 aydır olan öksürük, kilo kaybı ve vertebralarda litik lezyonlar ile başvuran ve metisiline dirençli S.aureus’a (MRSA) bağlı spondilodiskit tespit edilen Job’s sendromlu bir hasta, literatür verileri ışığında tartışılmıştır.