SavedAdd your journal

Journals / BEYOGLU EYE JOURNAL / 2022 / Cilt: 7 - Sayı: 2

Evaluation of Systemic Endothelial Dysfunction in Retinal Vein Occlusions

Erdinc BOZKURT
Turkhun ÇETİN
İbrahim RENCUZOİULLARI
Pages
126–133
Publication Date
2022-11-06
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: BCVA (logMAR) was 1.39±1.30 in patients with RVO and 0.028±1.22 in the control group (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: Our aim in this study was to evaluate the systemic endothelial dysfunction status and carotid intima-media thickness (CIMT) in patients with retinal vein occlusion (RVO).
📊
Key Findings & Data:Methods: Seventy-six patients who presented to the clinic with the diagnosis of RVO and 76 age- and gender-matched healthy individuals without a RVO history were included in the study.
💡
Conclusion & Impact:Results: BCVA (logMAR) was 1.39±1.30 in patients with RVO and 0.028±1.22 in the control group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Our aim in this study was to evaluate the systemic endothelial dysfunction status and carotid intima-media thickness (CIMT) in patients with retinal vein occlusion (RVO). Methods: Seventy-six patients who presented to the clinic with the diagnosis of RVO and 76 age- and gender-matched healthy individuals without a RVO history were included in the study. The patients’ best-corrected visual acuity (BCVA) and central macular thickness (CMT) were measures, and diabetes, hypertension, hyperlipidemia, carotid artery disease, body mass index, and smoking histories were recorded. The endothelial function levels of the patients, pulse wave velocity (PWV), flow-mediated dilation (FMD), and CIMT were measured. Endothelial dysfunction was detected by applying the FMD technique to the brachial artery. CIMT was evaluated by B-mode ultrasonography. Serum hematological parameters were evaluated. Results: BCVA (logMAR) was 1.39±1.30 in patients with RVO and 0.028±1.22 in the control group (p

🔖

Cite This Article

BOZKURT, E., ÇETİN, T., RENCUZOİULLARI, İ. (2022). Evaluation of Systemic Endothelial Dysfunction in Retinal Vein Occlusions. BEYOGLU EYE JOURNAL, Cilt: 7 - Sayı: 2, 126–133. https://ajindex.com/articles/649049

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Klein R, Moss SE, Meuer SM, Klein BE. The 15-year cumulative incidence of retinal vein occlusion: The Beaver Dam eye study. Arch Ophthalmol 2008;126:513–8
  2. Natural history and clinical management of central retinal vein occlusion. The central vein occlusion study group. Arch Ophthalmol 1997;115:486–91
  3. Rogers S, McIntosh RL, Cheung N, Lim L, Wang JJ, Mitchell P, et al. The prevalence of retinal vein occlusion: pooled data from population studies from the United States, Europe, Asia, and Australia. Ophthalmology 2010;117:313–9.e1
  4. Hayreh SS, Zimmerman MB, Podhajsky P. Incidence of various types of retinal vein occlusion and their recurrence and demographic characteristics. Am J Ophthalmol 1994;117:429–41
  5. Ip M, Hendrick A. Retinal vein occlusion review. Asia Pac J Ophthalmol (Phila) 2018;7:40–5
  6. Raitakari OT, Celermajer DS. Flow-mediated dilatation. Br J Clin Pharmacol 2000;50:397–404
  7. Yaylalı YT, Kucukaslan M. Endotel disfonksiyonu. Pamukkale Tıp Dergisi 2011;3:152–7
  8. Fathi R, Haluska B, Isbel N, Short L, Marwick TH. The relative importance of vascular structure and function in predicting cardiovascular events. J Am Coll Cardiol 2004;43:616–23
  9. Corretti MC, Anderson TJ, Benjamin EJ, Celermajer D, Charbonneau F, Creager MA, et al. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: A report of the international brachial artery reactivity task force. J Am Coll Cardiol 2002;39:257–65
  10. Celermajer DS, Sorensen KE, Gooch VM, Spiegelhalter DJ, Miller OI, Sullivan ID, et al. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 1992;340:1111–5
  11. Lerman A, Zeiher AM. Endothelial function: Cardiac events. Circulation 2005;111:363–8
  12. Gouliopoulos N, Siasos G, Moschos MM, Oikonomou E, Rouvas A, Bletsa E, et al. Endothelial dysfunction and impaired arterial wall properties in patients with retinal vein occlusion. Vasc Med 2020;25:302–8
  13. Lyu M, Lee Y, Kim BS, Kim HJ, Hong R, Shin YU, et al. Clinical significance of subclinical atherosclerosis in retinal vein occlusion. Sci Rep 2021;11:1–9
  14. Bourouki E, Oikonomou E, Moschos M, Siasos G, Siasou G, Gouliopoulos N, et al. Pseudoexfoliative glaucoma, endothelial dysfunction, and arterial stiffness: The role of circulating apoptotic endothelial microparticles. J Glaucoma 2019;28:749–55
  15. Guvenmez O, Kayiklik A. Association of intima-media thickness of internal c