Journals / Annals of Medical Research / 2019 / Cilt: 26 - Sayı: 8

A cost minimization analysis of intracameral cefuroxime and moxifloxacin in cataract surgery

Pages
1458–1461
Publication Date
2022-10-12
DOI
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The cost of the drugs used in the first group was 3 times higher than thesecond group.Conclusion: The antibiotics injected to the anterior chamber during cataract surgery have similar effectiveness, moxifloxacin injectionto the anterior chamber was found to be more advantageous in terms of cost, compared to the use of disposable cefuroxime.

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Objective & Hypothesis:Aim: In this study, we aim to perform Cost Minimization Analysis of cefuroxime and moxifloxacin, which have proven to have a similarefficacy in the prophylaxis of endophthalmitis after cataract surgery.Material and Methods: The records of 1097 patients who had undergone cataract surgery and intracameral antibiotic (cefuroxime,moxifloxacin) injection in 2018 were evaluated retrospectively.
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Key Findings & Data:Group 1 consisted of patients who received intracameral1mg/0.1ml cefuroxime and Group 2 consisted of patients who received intracameral 500 μg /0.1ml moxifloxacin.
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Conclusion & Impact:The cost of the drugs used in the first group was 3 times higher than thesecond group.Conclusion: The antibiotics injected to the anterior chamber during cataract surgery have similar effectiveness, moxifloxacin injectionto the anterior chamber was found to be more advantageous in terms of cost, compared to the use of disposable cefuroxime.
🔬Design:Research Article
📍Scope:2018 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: In this study, we aim to perform Cost Minimization Analysis of cefuroxime and moxifloxacin, which have proven to have a similarefficacy in the prophylaxis of endophthalmitis after cataract surgery.Material and Methods: The records of 1097 patients who had undergone cataract surgery and intracameral antibiotic (cefuroxime,moxifloxacin) injection in 2018 were evaluated retrospectively. Patients undergoing cataract surgery were divided into two groupsaccording to the type of antibiotic injected into the anterior chamber. Group 1 consisted of patients who received intracameral1mg/0.1ml cefuroxime and Group 2 consisted of patients who received intracameral 500 μg /0.1ml moxifloxacin. In the postoperativeperiod, patients in both groups received topical antibiotic drops containing 0.5% moxifloxacin and steroid drops containing 0.1%dexamethasone for 7 days.Results: The Group 1 consisted of 213 (19.4%) patients, of which 97 (45.5%) were male and 116 (54.5%) were female, while Group 2consisted of 884 (80.6) patients, of which 439 (49.7%) were male, and 445 (50.3%) were female (p=0.280). The groups were similarin terms of age and gender distribution of the patients. There was no significant difference in terms of the posterior capsule rupturedevelopment between the two groups (p=0.692).BCVA was statistically significant before and after surgery in both groups. None ofthe patients in both groups developed endophthalmitis. The cost of the drugs used in the first group was 3 times higher than thesecond group.Conclusion: The antibiotics injected to the anterior chamber during cataract surgery have similar effectiveness, moxifloxacin injectionto the anterior chamber was found to be more advantageous in terms of cost, compared to the use of disposable cefuroxime.

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Cite This Article

YUVACI, İ., BOZKURT, E., CUCEN, B., ATUM, M., UÇAK, T., CELİK, E., DOĞAN, E. (2022). A cost minimization analysis of intracameral cefuroxime and moxifloxacin in cataract surgery. Annals of Medical Research, Cilt: 26 - Sayı: 8, 1458–1461. https://ajindex.com/articles/446968

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References (11)

  1. Foster A. Changing patterns in global blindness. Community Eye Heal J 2008;21:37-9
  2. Aaberg TM, Flynn HW, Schiffman J, et al. Nosocomial acute-onset postoperative endophthalmitis survey: A 10- year review of incidence and outcomes. Ophthalmology 1998;105:1004-10 3. Kessel L, Flesner P, Andresen J, et al. Antibiotic prevention of postcataract endophthalmitis: a systematic review and meta-analysis. Acta Ophthalmol 2015;93:303-17
  3. Schwartz SG, Flynn HW, Grzybowski A, et al. Intracameral antibiotics and cataract surgery: endophthalmitis rates, costs, and stewardship. Ophthalmology 2016;123:1411-3
  4. Bowen RC, Zhou AX, Bondalapati S, et al. Comparative analysis of the safety and efficacy of intracameral cefuroxime, moxifloxacin and vancomycin at the end of cataract surgery: A meta-analysis. Br J Ophthalmol 2018;102:1268-76
  5. Nagot N, Domerg C, Villain M, et al. Effectiveness and safety of an intracameral injection of cefuroxime for the prevention of endophthalmitis after cataract surgery with or without perioperative capsular rupture. JAMA Ophthalmol 2016;134:810-6
  6. Haripriya A, Chang DF, Ravindran RD. Endophthalmitis reduction with intracameral moxifloxacin prophylaxis: analysis of 600 000 surgeries. Ophthalmology 2017;124:768- 75
  7. Linertová R, Abreu-González R, García-Pérez L, et al. Intracameral cefuroxime and moxifoxacin used as endophthalmitis prophylaxis after cataract surgery: Systematic review of effectiveness and cost-effectiveness. Clin Ophthalmol 2014;8:1515-22
  8. Trusko B, Thorne J, Jabs D, et al; Standardization of uveitis nomenclature (sun) project. the standardization of uveitis nomenclature (sun) project. development of a clinical evidence base utilizing informatics tools and techniques. Methods Inf Med 2013;52(3):259-65, S1-6 10. Shorstein NH, Winthrop KL, Herrinton LJ. Decreased postoperative endophthalmitis rate after institution of intracameral antibiotics in a northern california eye department. J Cataract Refract Surg 2013;39:8-14
  9. Chang DF, Braga-Mele R, Henderson BA, et al. Antibiotic prophylaxis of postoperative endophthalmitis after cataract surgery: results of the 2014 ASCRS member survey. J Cataract Refract Surg 2015;41:1300-5
  10. Barry P, Gardner S, Seal D. et al. ESCRS endophthalmitis study group. clinical observations associated with proven and unproven cases in the escrs study of prophylaxis of postoperative endophthalmitis after cataract surgery. J Cataract Refract Surg 2009;35:1523-31
  11. Bayhan HA, Takm