Journals / Anadolu Kardiyoloji Dergisi / 2011 / Cilt: 11 - Sayı: 3

Radionuclide evaluation of lung perfusion after transcatheter closure of patent ductus arteriosus: analysis of frequently used two different types of coils

Patent duktus arteriyozus’un kapatılması sonrası akciğer perfüzyonunun radyonüklit yöntemle değerlendirilmesi: Sık kullanılan iki farklı koil tipinin analizi - Özgün Araştırma

Pages
218–223
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Number of loops deployed at the pulmonary side >1.4 (specificity 77%, sensitivity 85%, area under the ROC curve 0.804, 95%CI 0.661-0.947, p1.85 (specificity 70%, sensitivity 77%, area under the ROC curve 0.747, 95%CI 0.423-0.790, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Impaired left lung perfusion (LLP) has been described after transcatheter closure of the patent ductus arteriosus (PDA).
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Key Findings & Data:Methods: A prospective study of 89 patients who underwent PDA occlusion using the Cook coils in 49 and the Gianturco coils in 40, was conducted.
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Conclusion & Impact:Number of loops deployed at the pulmonary side >1.4 (specificity 77%, sensitivity 85%, area under the ROC curve 0.804, 95%CI 0.661-0.947, p1.85 (specificity 70%, sensitivity 77%, area under the ROC curve 0.747, 95%CI 0.423-0.790, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Impaired left lung perfusion (LLP) has been described after transcatheter closure of the patent ductus arteriosus (PDA). In this study, we aimed to evaluate lung perfusion scans (LPSs) following occlusion of PDA with two frequently used coils: Cook detachable coil and Gianturco coil. Methods: A prospective study of 89 patients who underwent PDA occlusion using the Cook coils in 49 and the Gianturco coils in 40, was conducted. LPSs were performed after a median period of 18 months. The relationships between the LPSs and continuous variables were assessed by Pearson correlation analysis and the cut-off value of the best correlated parameters to predict abnormal LPSs obtained by the Receiver Operating Characteristic (ROC) analysis. Results: Decreased left lung perfusion (LLP) was found in 13 patients including 10 after using Cook coils and 3 after using Gianturco coils (p=0.077). LLP values were significantly correlated with the loops deployed at the pulmonary side, coil/ductal diameter ratio and number of coils deployed (p=0.002, p=0.006 and p=0.009, respectively). Number of loops deployed at the pulmonary side >1.4 (specificity 77%, sensitivity 85%, area under the ROC curve 0.804, 95%CI 0.661-0.947, p1.85 (specificity 70%, sensitivity 77%, area under the ROC curve 0.747, 95%CI 0.423-0.790, p

Özet

Amaç: Transkateter patent duktus arteriyozus (PDA) tedavisi sonrası sol akciğer perfüzyonun da bozulma daha önce bildirilmiştir. Bu çalışmada PDA tedavisinde sıkça kullanılan kontrollü salınımlı Cook koil ve kontrolsüz salınımlı Gianturco koil lerin sol akciğer perfüzyona etkisinin radyonüklit yöntemle değerlendirilmesi amaçlanmıştır. Yöntemler: Bu prospektif çalışmada 49 olguda Cook koil ve 40 olguda Gianturco koil kullanılmak üzere toplam 89 olgunun transkateter yöntemiyle PDA’sı kapatıldı. Olgular PDA tedavisinden medyan 18 ay sonra akciğer perfüzyon sintigrafisi yapıldı. Azalmış sol akciğer perfüzyonunu öngörebilecek parametreler incelendi. Akciğer sintigrafisi kantitatif değerleri ile hasta parametrelerinin istatistiksel ilişkisi Pearson korelasyon katsayısı ile hesaplandı, düşük akciğer perfüzyonunu predikte eden değişkenlerden optimal kestirim değeri bulabilmek için ‘Receiver Operating Characteristic’ (ROC) eğrisi analizi kullanıldı. Bulgular: Sol akciğer perfüzyonunda bozulma 10’u Cook koil kullanımı sonrası, 3 olgu Gianturco koil kullanımı sonrası olmak üzere toplam 13 olguda saptandı (p=0.077). Tüm olgular ele alındığında pulmoner arter tarafında bırakılan sarmal sayısı, koil/duktal çap oranı ve birden fazla koil kullanımı ile ilişkilidir (sırasıyla, p=0.002, p=0.006 ve p=0.009). Pulmoner arter tarafındaki sarmal sayısı 1.4 üzerindeki olgularda %77 özgüllük ve %85 duyarlılık ile ilk koil çapı/duktus en dar çapı oranı 1.85 üzerindeki olgular %70 özgüllük ve %77 duyarlılık ile akciğer perfüzyon sintigrafisinde bozulma öngörülebilmektedir (ROC eğrisi altındaki alanlar sırasıyla, 0.804, %95GA 0.661-0.947, p

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Cite This Article

AKDENİZ, C., POLAT, T. B., FIRAT, F., HACIMAHMUTOĞLU, S., ÇELEBİ, A., ERDEM, A. (2022). Radionuclide evaluation of lung perfusion after transcatheter closure of patent ductus arteriosus: analysis of frequently used two different types of coils. Anadolu Kardiyoloji Dergisi, Cilt: 11 - Sayı: 3, 218–223. https://ajindex.com/articles/648451

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