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Journals / Viral Hepatitis Journal / 2020 / Cilt: 26 - Sayı: 1

Relationship between Viral Load and Hepatic Histopathology in Patients with Chronic Hepatitis B

Kronik Hepatit B Tanılı Hastalarda Viral Yük ile Karaciğer Histopatolojisi İlişkisi

Raika DURUSOY
Meltem IŞIKGÖZ TAŞBAKAN
Hüsnü PULLUKÇU
Damla AKDAĞ
Tansu YAMAZHAN
Pages
1–4
Publication Date
2022-11-06
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Patients were divided into five groups (

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: It is not always possible to determine a clear relationship between the DNA level of hepatitis B virus (HBV) and histology.
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Key Findings & Data:In this study, we aimed to determine the relationship between HBV-DNA level and liver histopathology in patients with chronic hepatitis.Materials and Methods: Between 2008 and 2016, 361 patients diagnosed with chronic HBV infection were retrospectively examined with age, sex, hepatitis B e antigen status, alanine aminotransferase (ALT) and HBV-DNA levels and liver biopsy scores according to modified Ishak criteria.
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Conclusion & Impact:Patients were divided into five groups (
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: It is not always possible to determine a clear relationship between the DNA level of hepatitis B virus (HBV) and histology. In this study, we aimed to determine the relationship between HBV-DNA level and liver histopathology in patients with chronic hepatitis.Materials and Methods: Between 2008 and 2016, 361 patients diagnosed with chronic HBV infection were retrospectively examined with age, sex, hepatitis B e antigen status, alanine aminotransferase (ALT) and HBV-DNA levels and liver biopsy scores according to modified Ishak criteria. Patients were divided into five groups (

Özet

Amaç: Hepatit B virüs (HBV)-DNA düzeyi ile histoloji arasında her zaman net bir ilişki saptamak mümkün olmamaktadır. Bu çalışmada kronik hepatit tanılı hastalarda HBV-DNA düzeyi ile karaciğer histopatolojisi arasındaki ilişkinin ortaya konması amaçlanmıştır. Gereç ve Yöntemler: 2008-2016 yılları arasında kronik hepatit B tanılı 361 hastanın; yaş, cinsiyet, hepatit B e antijeni durumu, alanin aminotransferaz (ALT) ve HBV-DNA düzeyleri ile modifiye Ishak kriterlerine göre karaciğer biyopsi skorları retrospektif olarak incelenmiştir. HBV-DNA düzeyi ile grade/stage skorları arasındaki istatistiksel ilişkinin araştırılması açısından hastalar, HBV-DNA düzeyine göre 5 gruba (

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Cite This Article

DURUSOY, R., TAŞBAKAN, M. I., PULLUKÇU, H., AKDAĞ, D., YAMAZHAN, T. (2022). Relationship between Viral Load and Hepatic Histopathology in Patients with Chronic Hepatitis B. Viral Hepatitis Journal, Cilt: 26 - Sayı: 1, 1–4. https://ajindex.com/articles/646335

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