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Journals / Türk Uyku Tıbbı Dergisi / 2022 / Cilt: 9 - Sayı: 3

Poor Sleep Quality and Associated Factors in Patients with Common Variable Immunodeficiency

Yaygın Değişken İmmün Yetmezlik Hastalarında Kötü Uyku Kalitesi ve İlişkili Faktörler

Eray Yıldız
Şevket Arslan
Buket Tuğan Yıldız
Deniz Tuncel Berktaş
Fatih Çölkesen
Recep Evcen
Filiz Sadi Aykan
Mehmet Kılınç
Gökhan Aytekin
Adem Aydın
Pages
214–220
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The PSQI, HAM-A, HAM-D and FSS scores of the patients receiving IVIG treatment were higher than those of the patients receiving SCIG treatment (all, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: This study aimed to examine the sleep quality of common variable immunodeficiency (CVID) patients and to investigate the relationship between sleep quality and depression, anxiety, fatigue, excessive daytime sleepiness and naturel killer (NK) cell counts.
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Key Findings & Data:Materials and Methods: The study included 53 patients followed with CVID diagnosis.
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Conclusion & Impact:The PSQI, HAM-A, HAM-D and FSS scores of the patients receiving IVIG treatment were higher than those of the patients receiving SCIG treatment (all, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: This study aimed to examine the sleep quality of common variable immunodeficiency (CVID) patients and to investigate the relationship between sleep quality and depression, anxiety, fatigue, excessive daytime sleepiness and naturel killer (NK) cell counts. Materials and Methods: The study included 53 patients followed with CVID diagnosis. To determine sleep quality and conditions associated with sleep quality in CVID patients, Pittsburgh sleep quality index (PSQI), fatigue severity scale (FSS), Hamilton depression scale (HAM-D), Hamilton anxiety scale (HAM-A) and Epworth sleepiness scale (ESS) were used. Results: Fatigue was found in 37 (70%) patients, poor sleep quality in 34 (64%), depression in 20 (38%), anxiety in 16 (30%), and excessive daytime sleepiness in 11 (21%) patients. All patients CVID patients received immunoglobulin replacement therapy: Intravenous immunoglobulin (IVIG) in 37 (72%) and subcutaneous immunoglobulin (SCIG) in 16 (28%) patients. The PSQI, HAM-A, HAM-D and FSS scores of the patients receiving IVIG treatment were higher than those of the patients receiving SCIG treatment (all, p

Özet

Amaç: Bu çalışmanın amacı, yaygın değişken immün yetmezlik (YDİY) hastalarının uyku kalitesini incelemek ve uyku kalitesi ile depresyon, anksiyete, yorgunluk, gündüz aşırı uyku hali ve doğal öldürücü (NK) hücre sayıları arasındaki ilişkiyi araştırmaktır. Gereç ve Yöntem: Çalışmaya YDİY tanısı ile takip edilen toplam 53 hasta dahil edilmiştir. YDİY hastalarında uyku kalitesi ve uyku kalitesi ile ilişkili durumları belirlemek için Pittsburgh uyku kalitesi indeksi (PUKİ), yorgunluk şiddet ölçeği (YŞÖ), Hamilton depresyon ölçeği (HAM-D), Hamilton anksiyete ölçeği (HAM-A) ve Epworth uykululuk ölçeği (EUÖ) kullanılmıştır. Bulgular: Hastaların 37’sinde (%70) yorgunluk, 34’ünde (%64) kötü uyku kalitesi, 20’sinde (%38) depresyon, 16’sında (%30) anksiyete ve 11’inde (%21) gündüz aşırı uykululuğu saptanmıştır. Tüm YDİY hastaları immünoglobulin (IVIG) replasman tedavisi almakta idi [37 (%72) hastada intravenöz IVIG ve 16 (%28) hastada subkütan immünoglobulin (SCIG)]. IVIG tedavisi alan hastaların PUKİ, HAM-A, HAM-D ve YŞÖ skorları SCIG tedavisi alan hastalardan daha yüksekti (tümü, p

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Cite This Article

Yıldız, E., Arslan, Ş., Yıldız, B. T., Berktaş, D. T., Çölkesen, F., Evcen, R., Aykan, F. S., Kılınç, M., Aytekin, G., Aydın, A. (2022). Poor Sleep Quality and Associated Factors in Patients with Common Variable Immunodeficiency. Türk Uyku Tıbbı Dergisi, Cilt: 9 - Sayı: 3, 214–220. https://ajindex.com/articles/643227

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References (12)

  1. Bousfiha A, Jeddane L, Picard C, Al-Herz W, Ailal F, Chatila T, Cunningham-Rundles C, Etzioni A, Franco JL, Holland SM, Klein C, Morio T, Ochs HD, Oksenhendler E, Puck J, Torgerson TR, Casanova JL, Sullivan KE, Tangye SG. Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. J Clin Immunol 2020;40:66-81
  2. Bousfiha A, Jeddane L, Picard C, Ailal F, Bobby Gaspar H, Al-Herz W, Chatila T, Crow YJ, Cunningham-Rundles C, Etzioni A, Franco JL, Holland SM, Klein C, Morio T, Ochs HD, Oksenhendler E, Puck J, Tang MLK, Tangye SG, Torgerson TR, Casanova JL, Sullivan KE. The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies. J Clin Immunol 2018;38:129-43
  3. Bonilla FA, Barlan I, Chapel H, Costa-Carvalho BT, Cunningham- Rundles C, de la Morena MT, Espinosa-Rosales FJ, Hammarström L, Nonoyama S, Quinti I, Routes JM, Tang ML, Warnatz K. International Consensus Document (ICON): Common Variable Immunodeficiency Disorders. J Allergy Clin Immunol Pract 2016;4:38-59
  4. Adelman DC, Howard K. Assessing Quality of Life in Patients with Common Variable Immunodeficiency: Why It Matters. J Allergy Clin Immunol Pract 2016;4:1180-1
  5. Gardulf A, Nicolay U, Math D, Asensio O, Bernatowska E, Böck A, Costa-Carvalho BT, Granert C, Haag S, Hernández D, Kiessling P, Kus J, Matamoros N, Niehues T, Schmidt S, Schulze I, Borte M. Children and adults with primary antibody deficiencies gain quality of life by subcutaneous IgG self-infusions at home. J Allergy Clin Immunol 2004;114:936-42
  6. Tcheurekdjian H, Palermo T, Hostoffer R. Quality of life in common variable immunodeficiency requiring intravenous immunoglobulin therapy. Ann Allergy Asthma Immunol 2004;93:160-5
  7. Bansal RA, Tadros S, Bansal AS. The presence of overlapping quality of life symptoms in primary antibody deficiency (PAD) and chronic fatigue syndrome (CFS). Allergy Asthma Clin Immunol 2020;16:21
  8. Lashley FR. A review of sleep in selected immune and autoimmune disorders. Holist Nurs Pract 2003;17:65-80
  9. Besedovsky L, Lange T, Born J. Sleep and immune function. Pflugers Arch 2012;463:121-37
  10. Fondell E, Axelsson J, Franck K, Ploner A, Lekander M, Bälter K, Gaines H. Short natural sleep is associated with higher T cell and lower NK cell activities. Brain Behav Immun 2011;25:1367-75
  11. Agargun MY, Kara H, Anlar O. The Validity and Reliability of the Pittsburgh Sleep Quality Index. Turkish Journal of Psychiatry 1996;7:107-11
  12. Armutlu K, Korkmaz NC, Keser I, Sum