Journals / Türk Psikiyatri Dergisi / 2021 / Cilt: 32 - Sayı: 1

Maintenance Electroconvulsive Therapy for Agitation and Self- Injurious Behaviors in Autism Spectrum Disorder

İdame Elektrokonvülsif Terapinin Otizm Spektrum Bozukluğunda Ajitasyon ve Kendine Zarar Verme Davranışlarının Tedavisinde Kullanımı

Pages
65–69
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Our paper is among the few that reported succesful treatment of agitation with m-ECT. m-ECT should be considered in treatment resistant cases.

📌 3 Key Takeaways

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Objective & Hypothesis:Self-injurious behaviors (SIBs) in autism spectrum disorder (ASD) are destructive symptoms that can lead to dangerous injuries and life-threatening risks.
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Key Findings & Data:This report presents the clinical features and the course of m-ECT on two cases under follow up for pharmacotherapy resistant ASD with significant agitation, mood disorder and SIBs that could cause severe head traumas.
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Conclusion & Impact:Our paper is among the few that reported succesful treatment of agitation with m-ECT. m-ECT should be considered in treatment resistant cases.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Self-injurious behaviors (SIBs) in autism spectrum disorder (ASD) are destructive symptoms that can lead to dangerous injuries and life-threatening risks. Agitation and SIBs may not respond to psychopharmacological and behavioral interventions. There are reports in the literature on improvement after electroconvulsive therapy (ECT) in cases not responding pharmacotherapy. However, data on the efficacy of the therapy on the benefiting patients, the course of the treatment and on the use of maintenance ECT (m-ECT) are very limited. This report presents the clinical features and the course of m-ECT on two cases under follow up for pharmacotherapy resistant ASD with significant agitation, mood disorder and SIBs that could cause severe head traumas. The initial stage of therapy consisted of 7 sessions of ECT patients showed improvement after the 5th session. m-ECT were started since the agitation repeated one week after discharge despite ongoing pharmacotherapy. In the first case, m-ECT was continued once every two weeks for a total of 46 sessions; and in the second case a total of 18 weekly sessions were conducted. No significant side effects or complications were observed and the general state of well-being was preserved. Our paper is among the few that reported succesful treatment of agitation with m-ECT. m-ECT should be considered in treatment resistant cases.

Özet

Otizm spektrum bozukluğunda (OSB) kendine zarar verme davranışı, sıklıkla tehlikeli doku yaralanmasına ve hayati risklere yol açabilecek yıkıcı belirtilerden biridir. Bu tür durumlarda kendine zarar verme davranışı ve saldırganlık, psikofarmakolojik ve davranışsal girişimlere cevap vermeyebilir. Yazında ilaç tedavilerine yanıt alınamayan ve elektrokonvülsif terapiyle (EKT) iyileşme görülen olgular yer almaktadır; ancak fayda gören olgularda terapinin etkinliği, tedaviye nasıl devam edileceği ve idame EKT (i-EKT) ile ilgili sınırlı bilgi mevcuttur. Bu çalışmada OSB tanısı ile izlenen; ilaç tedavilerine yanıt vermeyen belirgin ajitasyon, duygudurum bozukluğu, ağır kafa travmasına neden olacak kendine zarar verme davranışları olan iki olgunun klinik özellikleri, tedavi süreci ve i-EKT tedavisi sunulmuştur. İlk tedavi aşamasında EKT 7 seans olarak planlanmış ve olguların 5. seans sonrası iyileşme gösterdiği gözlenmiştir. Ancak taburcu edildikten sonra devam eden ilaca rağmen bir hafta sonra tekrarlayan ajitasyon sebebiyle i-EKT’nin uygulanmasına karar verilmiştir. İlk olguda i-EKT’ye iki haftada bir toplam 46 seans, ikinci olguda ise haftalık olmak üzere toplam 18 seans olarak devam edilmiştir. Tedaviye bağlı belirgin bir yan etki ya da komplikasyon gözlenmemiş ve genel iyilik hali devam etmiştir. Çalışmamız OSB tanısı konulan hastalarda görülen ajitasyonun i-EKT ile tedavi edildiği kısıtlı sayıda olgulardan birisidir ve sonuçlara dayanarak i-EKT, ilaca dirençli olgularda bir tedavi seçeneği olarak düşünülebilir.

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Cite This Article

KARDEŞ, V. Ç., GİRGEÇ, S. K., ÇELİK, S., AKMAN, Ö. A., ATASOY, N. (2022). Maintenance Electroconvulsive Therapy for Agitation and Self- Injurious Behaviors in Autism Spectrum Disorder. Türk Psikiyatri Dergisi, Cilt: 32 - Sayı: 1, 65–69. https://ajindex.com/articles/641937

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References (16)

  1. Ak İ (2018) Sürdürüm/idame elektrokonvülsif terapi. Türkiye Klinikleri Psikiyatri -Özel Konular 11: 71-4.
  2. Amerikan Psikiyatri Birliği (2013) Ruhsal Bozuklukların Tanısal ve Sayımsal El Kitabı, Beşinci Baskı (DSM-V) (Çev. ed.: E Köroğlu). Ankara, Hekimler Yayın Birliği, 2013.
  3. American Psychiatric Association (2008) The practice of electroconvulsive therapy: recommendations for treatment, training, and privileging (A task force report of the American Psychiatric Association). American Psychiatric Press.
  4. Bilgi MM, Eker Ç, Gönül AS (2010) İdame elektrokonvulzif tedavi. Psikiyatride Güncel Yaklaşımlar 2: 421-42.
  5. Bilici R, Sercan M, Tufan AE (2013) Psikiyatrik hastalarda saldırganlık ve saldırgan hastaya yaklaşım. Düşünen Adam 26: 190-8.
  6. Breen J, Hare DJ (2017) The nature and prevalence of catatonic symptoms in young people with autism. JIDR 61: 580-93.
  7. Dhosssche DM, Shah A, Wing L (2006) Blueprints for assessment, treatment, and future study of catatonia in autism spectrum disorders. Int Rev Neurobiol 72: 267–84.
  8. Dominick KC, Davis NO, Lainhart J ve ark. (2007) Atypical behaviors in children with autism and children with a history of language impairment. Res Dev Disabil 28: 145-62.
  9. Duerden EG, Oatley HK, Mak-Fan KM ve ark. (2012) Risk factors associated with self-injurious behaviors in children and adolescents with autism spectrum disorders. J Autism Dev Disord 42: 2460-70.
  10. Ellawala TI (2015) The efficacy of electroconvulsive therapy in managing selfinjurious behaviors among youth with autism spectrum disorder: A review. Scholarly Undergraduate Research Journal at Clark 1: 18-26.
  11. Ghaziuddin N, Gih D, Barbosa V ve ark. (2010) Onset of catatonia at puberty: electroconvulsive therapy response in two autistic adolescents. The Journal of ECT 26: 274-7.
  12. Glass OM, Forester BP, Hermida AP (2017) Electroconvulsive therapy (ECT) for treating agitation in dementia (majör neurocognitive disorder)-a promising option. Int Psychogeriatr 29: 717-26.
  13. Haq AU, Ghaziuddin N (2014) Maintenance electroconvulsive therapy for aggression and self-injurious behavior in two adolescents with autism and catatonia. J Neuropsychiatry Clin Neurosci 26: 64-72.
  14. Hare DJ, Malone C (2004) Catatonia and autistic spectrum disorders. Autism 8: 183-95.
  15. Matson JL, Matson ML, Rivet TT (2007) Social-skills treatments for children with autism spectrum disorders: An overview. Behav Modif 31: 682-707.
  16. Mazzone L, Postorino V, Valeri G ve ark. (2014) Catatonia in patients with autism: prevalence and managemen