Journals / Türk Oftalmoloji Dergisi / 2003 / Cilt: 33 - Sayı: 1

Conjunctival intraepithelial and invasive squamous cell neoplasias

Konjonktivanın intraepitelyal ve invaziv skuamöz hücreli neoplazileri

Pages
11–15
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Performing excision with cryotherapy in the same session and closing the conjunctival openings by suitable methods in selected cases results in proper treatment of con-junctival squamous cell neoplasias.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To evaluate the clinical signs and treatment results of conjunctival squamous cell neoplasia.
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Key Findings & Data:Methods: 10 cases that have applied to İzmir Atatürk Education and Research Hospital Eye Clinic between May 1999 - May 2001 were examined retrospectively according to their clinical signs, treatment modalities and results.
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Conclusion & Impact:Conclusion: Performing excision with cryotherapy in the same session and closing the conjunctival openings by suitable methods in selected cases results in proper treatment of con-junctival squamous cell neoplasias.
🔬Design:Research Article
📍Scope:2001 Verileri
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate the clinical signs and treatment results of conjunctival squamous cell neoplasia. Methods: 10 cases that have applied to İzmir Atatürk Education and Research Hospital Eye Clinic between May 1999 - May 2001 were examined retrospectively according to their clinical signs, treatment modalities and results. Results: The average age of 5 men and 5 women included in the study was 61 years (range, 32 - 73). Total excision with a surrounding 4 mm healthy conjunctival tissue and cryotherapy with double freeze and thaw technique were applied to all patients. Lamellar sclerectomy was performed in 2 cases in which scleral invasion was observed during operation. Oral mucosal greft was used in 2 eyes with large conjunctival openings. Limbal autogreft transplantation was performed in 1 case in which the lesion invaded nearly all of limbal circumference. Histopathology revealed intraepithelial squamous cell carcinoma in 7 cases and invasive squamous cell carcinoma in 3 patients. Recurrence was seen in only one patient throughout 14 months (range, 10 - 18) of mean follow up time. Conclusion: Performing excision with cryotherapy in the same session and closing the conjunctival openings by suitable methods in selected cases results in proper treatment of con-junctival squamous cell neoplasias.

Özet

Amaç: Konjonktival skuamöz hücreli neoplazilerin klinik bulgularını ve tedavi sonuçlarını bildirmek. Yöntem: Mayıs 1999 - Mayıs 2001 tarihleri arasında İzmir Atatürk Eğitim ve Araştırma Hastanesi Göz Kliniği'nde görülen 10 olgu; klinik görünümleri, tedavi şekilleri ve sonuçları açısından retrospektif olarak değerlendirildi. Bulgular: Yaş ortalaması 61 (sınırlar, 32 - 73 yaş) olan 10 hastanın 5'i erkek, 5'i kadın idi. Tüm olgulara en az 4 mm sağlam konjonktiva dokusu bırakılarak total eksizyon ve çift dondurma - çözme yöntemiyle kriyoterapi uygulandı. Cerrahi sırasında, sklera invazyonu gözlenen iki olguya lameller sklerektomi yapıldı. Geniş konjonktiva açıklığı olan 2 gözde ağız mukoza grefti kullanıldı. Hemen hemen tüm limbusu kapsayan lezyonu olan bir olguya limbal otogreft trans-plantasyonu yapıldı. Histopatolojik inceleme sonuçlan 7 hastada İntraepitelyal karsinom, 3 hastada invaziv skuamöz hücreli karsinom ile uyumlu bulundu. Ortalama izlem süresi 14 ay (sınırlar, 10 - 18 ay) olan olguların l'inde nüks saptandı. Sonuç: Eksizyon ile kriyoterapinin birlikte uygulanması ve gereken olgularda konjonktiva açıklığının uygun yöntemlerle kapatılması, konjonktivanın skuamöz hücreli neoplazilerin etkin tedavisini sağlamaktadır.

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Cite This Article

YILMAZ, A., MADEN, A., UĞURLU, Ş., YURDAKUL, S. N. (2022). Conjunctival intraepithelial and invasive squamous cell neoplasias. Türk Oftalmoloji Dergisi, Cilt: 33 - Sayı: 1, 11–15. https://ajindex.com/articles/638975

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