Journals / Türk Oftalmoloji Dergisi / 2006 / Cilt: 36 - Sayı: 2

Fundus fluorescein angiographic findings in patients with Behçet's disease with no clinical ocular involvement

Klinik olarak oküler tutulumu olmayan Behçet hastalarında fundus floresein anjiyografi bulguları

Pages
156–159
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In order to evaluate ocular involvement during the diagnosis of Behcet's Disease, a more objective method, FFA, is needed in conjunction with detailed ophthalmological examination.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To evaluate the posterior segment by fundus fluorescein angiography (FFA) in Behçet patients with no clinical ocular involvement.Methods: Sixty-five eyes of 33 Behçet patients (female/male: 13/20, mean age: 35.1) diag¬nosed according to the criteria of International Study Group for Behcet's Disease were included in this study.
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Key Findings & Data:Results: Twentyfive out of 65 eyes (38.5%) had some kind of angiographic abnormalities, and rest (40 eyes, 61.5%) had normal FFAs.
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Conclusion & Impact:In order to evaluate ocular involvement during the diagnosis of Behcet's Disease, a more objective method, FFA, is needed in conjunction with detailed ophthalmological examination.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate the posterior segment by fundus fluorescein angiography (FFA) in Behçet patients with no clinical ocular involvement.Methods: Sixty-five eyes of 33 Behçet patients (female/male: 13/20, mean age: 35.1) diag¬nosed according to the criteria of International Study Group for Behcet's Disease were included in this study. All cases had a negative history for ocular involvement, and were found to have normal biomicroscopic and fundoscopic (with Goldmann's three-mirror lens) examinations. Int¬raocular pressures were within normal limits. No patient had any systemic condition other than Behcet's Disease. All cases underwent FFA using Topcon digital image analysis system. Results: Twentyfive out of 65 eyes (38.5%) had some kind of angiographic abnormalities, and rest (40 eyes, 61.5%) had normal FFAs. Pathological findings include staining of the optic disc in 17 eyes, patchy filling of choroid in 7 eyes, "window defects" due to retinal pigment epithelium atrophy in 5 eyes, and retinal vessel tortuosity in 3 eyes. Conclusion: We have documented pathological fluorescein angiographic findings in Beh-cet patients with no clinical ocular involvement. In order to evaluate ocular involvement during the diagnosis of Behcet's Disease, a more objective method, FFA, is needed in conjunction with detailed ophthalmological examination.

Özet

Amaç: Oküler tutulumu olmayan Behçet olgularında arka segmentin fundus floresein anji¬yografi (FFA) ile değerlendirilmesi. Metod: Uluslararası Behçet Hastalığı Çalışma drubu tanı kriterlerine göre Behçet hastalı¬ğı tanısı alan 33 hastanın (K/E: 13/20, yaş ortalaması: 35.1 yıl) 65 gözü çalışma kapsamına alındı. Öykülerinde Behçet Hastalığı'na bağlı göz tutulumu olmayan hastaların biyomikroskopik ön segment muayeneleri ve Goldmann'ın üç aynalı lensi ile yapılan fundus muayeneleri normal olarak değerlendirildi. Göziçi basınçları normal sınırlarda idi. Olguların hiçbirinde Behçet has¬talığı haricinde tespit edilen sistemik patoloji yoktu. Tüm olguların FFA'ları Topcon IMAGEnet Dijital Görüntüleme Sistemi kullanılarak çekildi. Bulgular: Toplam 65 gözün 25'inde (%38.5) anjiyografik patoloji saptanırken, 40 gözde (%61.5) FFA normal olarak değerlendirildi. FFA'da, 17 gözde optik diskte geç dönemde boyan¬ma, 7 gözde koroid damarlarında parçalı dolum, 5 gözde retina pigment epiteli atrofisine bağlı pencere def ekti ve 3 gözde retina damarlarında kıvrımlanma artışı patolojik bulgu olarak tespit edildi. Sonuç: Klinik bakıda oküler tutulumu olmayan Behçet hastalarının FFA'larında patolojik bulgular saptanmıştır. Behçet Hastalığı tanısında göz tutulumunun değerlendirilmesini objektif kriterlere dayandırmak amacıyla olguların FFA ile incelenmesinin uygun olacağı kanısındayız.

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Cite This Article

YILDIRIM, C., IŞIK, C., GÜNGEN, Ş., YAYLALI, V., ÖZDEN, S., TATLIPINAR, S. (2022). Fundus fluorescein angiographic findings in patients with Behçet's disease with no clinical ocular involvement. Türk Oftalmoloji Dergisi, Cilt: 36 - Sayı: 2, 156–159. https://ajindex.com/articles/638762

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