Journals / Türk Oftalmoloji Dergisi / 2006 / Cilt: 36 - Sayı: 2

Effect of age on the retinal nerve fiber layer thickness and standard parameters of GDx

Yaşın retinal sinir lifi tabakası kalınlığı ve GDx'in standart parametreleri üzerine etkisi

Pages
160–165
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The area with the thickest RNFL in the peripapillary area is the inferior quad¬rant, and the integral values of the total, superior and inferior quadrant are decreased with age while the number parameter is increased.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To investigate the age related changes on the retinal nerve fiber layer thickness (RNFL) and the effects thereof on the standard parameters of Scanner Laser Polarimeter (GDx).Method: 100 cases, examining to the Department of Ophthalmology, School of Medicine, Trakya University, with a refractive error less than 1 diopters in spheric equivalent and a cup/disc rate of less than 0.4, who did not have media opacity or history of retinal disorder and glaucoma, were included into the study.
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Key Findings & Data:One eye of each case was selected randomly and the integral values for the total and four quadrants of 100 eyes of the 100 cases were investigated along with the age-related changes in the standard parameters of GDx.
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Conclusion & Impact:Conclusion: The area with the thickest RNFL in the peripapillary area is the inferior quad¬rant, and the integral values of the total, superior and inferior quadrant are decreased with age while the number parameter is increased.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To investigate the age related changes on the retinal nerve fiber layer thickness (RNFL) and the effects thereof on the standard parameters of Scanner Laser Polarimeter (GDx).Method: 100 cases, examining to the Department of Ophthalmology, School of Medicine, Trakya University, with a refractive error less than 1 diopters in spheric equivalent and a cup/disc rate of less than 0.4, who did not have media opacity or history of retinal disorder and glaucoma, were included into the study. Following the ophthalmologic examination of all ca¬ses, GDx images of both eyes were taken. One eye of each case was selected randomly and the integral values for the total and four quadrants of 100 eyes of the 100 cases were investigated along with the age-related changes in the standard parameters of GDx. Results: Based on the findings from the GDx images of the cases with an age average of 40.68±13.Q8; the quadrant with the thickest peripapillary RNFL was the inferior quadrant, which was followed by the superior, nasal and temporal integral values. Moreover, a negative correlation was determined between age and the total, superior and inferior integral values (p=0.008, p=0.005, p=0.002). A negative correlation was determined between age and the GDx parameters of maximal modulation (p=0.044), average thickness (p=0.008), ellipse average (p=0.004), superior average (p=0.002) and inferior average (p=0.001), and a positive correlation was determined with the number parameter (p=0.015). Conclusion: The area with the thickest RNFL in the peripapillary area is the inferior quad¬rant, and the integral values of the total, superior and inferior quadrant are decreased with age while the number parameter is increased.

Özet

Amaç: Retinal sinir lifi tabakası kalınlığında (RSLT) ortaya çıkan yaşa bağlı değişiklikleri ve bunların Tarayıcı Laser Polarimetre'nin (GDx) standart parametreleri üzerine etkilerini araş¬tırmak. Yöntem: Trakya Üniversitesi Tıp Fakültesi GözJHastalıkları Anabilim Dalı Polikliniğine başvuran olgulardan; kırma kusura sferik eşdeğeri 1 dioptriden fazla olmayan, ortam opasitesi bulunmayan, retinal hastalık ve glokom öyküsü olmayan ve cup/disk oranı 0.4'ten az olan 100 olgu çalışmaya alındı. Olguların tümünün oftalmolojik muayeneleri yapıldıktan sonra her iki gözünden GDx görüntüleri alındı. Her olgunun bir gözü rastlantısal olarak seçilerek, 100 olgu¬nun 100 gözüne ait total ve dört kadrana ait integral değerleri ile GDx'in standart parametrele-rindeki yaşa bağlı değişiklikler araştırıldı. Bulgular: Yaş ortalaması 40.68±13.08 olan,olguların GDx görüntülerinden elde edilen so¬nuçlara göre; peripapiller RSLT'nin en kalın olduğu kadran inferior kadrandı ve bunu sırası ile superior, nasal ve temporal integral değerleri izlemekte idi. Ayrıca, yaş ile total, superior ve in¬ferior integral değerleri arasında negatif korelasyon mevcuttu (p=0.008, p=0.005, p=0.002). Yaş ile GDx parametrelerinden maximal modulation (p=0.044), superior maximum (p=0.008), infe¬rior maximum (p=0.003), average thickness (p=0.008), ellipse average (p=0.004), superior ave¬rage (p=0.002) ve inferior average (p=0.001) arasında negatif korelasyon ve number (p=0.015) ile pozitif korelasyon saptandı. Tartışma: Peripapiller alanda RSLT kalınlığının en fazla olduğu alan inferior kadrandır ve yaşla birlikte total, superior ve inferior kadranlara ait integral değerleri azalmakta, bunlara bağlı olarak standart parametrelerde de değişiklikler olmaktadır.

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Cite This Article

ALİMGİL, M. L., GÜRLÜ, P. V., SAMUT, H. S., ÖZKAN, H. (2022). Effect of age on the retinal nerve fiber layer thickness and standard parameters of GDx. Türk Oftalmoloji Dergisi, Cilt: 36 - Sayı: 2, 160–165. https://ajindex.com/articles/638734

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