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Journals / Türk Oftalmoloji Dergisi / 2007 / Cilt: 37 - Sayı: 6

Evaluation of factors affecting the donor corneal endothelium

Penetran keratoplasti öncesinde ve sonrasında donör kornea endoteline etki eden faktörlerin değerlendirilmesi

C. Banu COŞAR
Tansu GÖNEN
Suphi ACAR
Pages
406–413
Publication Date
2022-11-05
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

The mean corneal endothelial cell density was 1460±130.3 (635-2546) cells/mm2 at 3-months and 1219±98.5 (504-2130) cells/mm2 at 6-months postoperatively and this difference was statistically significant (p

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Objective & Hypothesis:PURPOSE: To evaluate the effect of death-to-harvesting time, harvesting-to-transplantation time, age of the donor and the host, and preoperative host corneal endothelial cell density on postoperative corneal endothelial cell density and central corneal thickness.
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Key Findings & Data:METHODS: Eighteen eyes of 18 patients who underwent penetrating keratoplasty were prospectively involved in this study.
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Conclusion & Impact:The mean corneal endothelial cell density was 1460±130.3 (635-2546) cells/mm2 at 3-months and 1219±98.5 (504-2130) cells/mm2 at 6-months postoperatively and this difference was statistically significant (p
🔬Design:Modeling & Simulation
📍Scope:2000 Verileri
⚙️Variables:Domain Parameters

Abstract

PURPOSE: To evaluate the effect of death-to-harvesting time, harvesting-to-transplantation time, age of the donor and the host, and preoperative host corneal endothelial cell density on postoperative corneal endothelial cell density and central corneal thickness. METHODS: Eighteen eyes of 18 patients who underwent penetrating keratoplasty were prospectively involved in this study. A specular microscope was used to evaluate the endothelial cell density preoperatively (Konan Eye Bank Kerato Analyzer, Model EKA-98, Japan) and at 3- and 6- months postoperatively (Tomey Endothelium Specular Microscope, EM-2000, Germany). Pachymetric measurement of the central donor cornea was performed at 1- week, 1-, 3- and 6-months postoperatively (Tomey, SP-3000, Germany). RESULTS: The mean preoperative corneal endothelial cell density was 2097±85.7 (1656-2985) cells/mm2. The mean corneal endothelial cell density was 1460±130.3 (635-2546) cells/mm2 at 3-months and 1219±98.5 (504-2130) cells/mm2 at 6-months postoperatively and this difference was statistically significant (p

Özet

AMAÇ: Donör kornealarda, ölüm-alım ve alım-nakil sürelerinin, donör ve alıcı yaşlarının, cerrahi öncesi merkezi kornea endotel hücre yoğunluğunun, cerrahi sonrası dönemde merkezi kornea endotel hücre yoğunluğu ile merkezi kornea kalınlığı üzerine etkilerini araştırmak. YÖNTEM: Prospektif olarak penetran keratoplasti operasyonu yapılan 18 hastanın 18 gözü çalışmaya dahil edildi. Donör korneanın merkezi endotel hücre yoğunluğu, cerrahi öncesinde ve cerrahiden sonra 3. ve 6. ayda speküler mikroskop (Konan Eye Bank Kerato Analyzer, Model EKA-98, Japonya ve Tomey Endothelium Specular Microscope, EM-2000, Almanya) ile değerlendirildi. Merkezi kornea kalınlığı cerrahi sonrası 1. hafta, 1. ay, 3. ay ve 6. ayda pakimetri (Tomey, SP-3000, Almanya) cihazı kullanılarak ölçüldü. BULGULAR: Cerrahi öncesinde ortalama merkezi kornea endotel hücre yoğunluğu 2097±85.7 (1656-2985) hücre/mm2 idi. Cerrahiden sonra üçüncü ayda ortalama merkezi kornea endotel hücre yoğunluğu 1460±130.3 (635-2546), 6. ayda 1219±98.5 (504-2130) hücre/mm2 olarak saptandı. Elde edilen bu ortalama değerler arasında istatistiksel olarak anlamlı bir fark ve 3 ve 6. ay değerleri arasında doğru orantılı bir korelasyon mevcuttu (sırasıyla p

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Cite This Article

COŞAR, C. B., GÖNEN, T., ACAR, S. (2022). Evaluation of factors affecting the donor corneal endothelium. Türk Oftalmoloji Dergisi, Cilt: 37 - Sayı: 6, 406–413. https://ajindex.com/articles/638687

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