Journals / Türk Oftalmoloji Dergisi / 2007 / Cilt: 37 - Sayı: 1

Efficacy and complications of subtenon depo steroid injections in uveitic patients by subtenon canulla

Üveitli hastalarda subtenon kanül ile depo steroid enjeksiyonlarının etkinlik ve komplikasyonları

Pages
23–29
Publication Date
2022-11-05
DOI
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Two patients had IOP rise requiring therapy. one had an epileptiform contraction during injection. one had infection of the incision wound.Conclusion : Posterior depo steroid injections performed with subtenon canulla had a low complication potential with high efficacy on a selected group of patients.

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Objective & Hypothesis:Purpose : Evaluation of therapoetic efficacy and complications of depo steroid injection by subtenon canulla on uveitic patient group is aimed.Methods : In patients with uveitis. following 4-5mm inferotemporal conjunctival incision. 40mg of depo steroid was quickly injected to the posterior subtenon space by a subtenon canulla.
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Key Findings & Data:Patients were evaluated for complications during injection. visual acuity. intraocular pressure and uveitic reactions during the first and third months.Results : In the study group. 17 eyes of 15 patients with a mean age of 29.3 ± 12.4 years were evaluated.
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Conclusion & Impact:Two patients had IOP rise requiring therapy. one had an epileptiform contraction during injection. one had infection of the incision wound.Conclusion : Posterior depo steroid injections performed with subtenon canulla had a low complication potential with high efficacy on a selected group of patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose : Evaluation of therapoetic efficacy and complications of depo steroid injection by subtenon canulla on uveitic patient group is aimed.Methods : In patients with uveitis. following 4-5mm inferotemporal conjunctival incision. 40mg of depo steroid was quickly injected to the posterior subtenon space by a subtenon canulla. Patients were evaluated for complications during injection. visual acuity. intraocular pressure and uveitic reactions during the first and third months.Results : In the study group. 17 eyes of 15 patients with a mean age of 29.3 ± 12.4 years were evaluated. Etiology for uveitis was Behçet´s disease in 6 (40.0%). intermediate uveitis in 3 (20.0%). Vogt-Koyonagi-Harada syndrome in one (6.7%). ankylosing spondylitis in one (6.7%). resistant iridocyclitis in one (6.7%) and undetermined posterior uveitis in 3 (20.0%). Initial visual acuity before subtenon steroid injection was 0.49 ± 0.31 on Snellen chart. 0.59 ± 0.32 on the first month and 0.68 ± 0.37 on the third month (p=0.002). IOP by applanation tonometry was 14.6 ± 3.8 mmHg at baseline. 16.7 ± 6.0 on the first month and 13.9 ± 3.6 mmHg on the third month (p=0.07). Two patients had IOP rise requiring therapy. one had an epileptiform contraction during injection. one had infection of the incision wound.Conclusion : Posterior depo steroid injections performed with subtenon canulla had a low complication potential with high efficacy on a selected group of patients.

Özet

Amaç : Subtenon kanül yardımıyla depo steroid enjeksiyonu yapılan üveitli hasta grubunda tedavi etkinliğinin ve gelişen komplikasyonların değerlendirilmesi hedeflendi.Yöntem : Üveitli hastalarımıza alt temporal alandan 4-5mmlik konjonktiva insizyonundan sonra 40mg depo steroid subtenon kanülle posterior subtenon boşluğa hızlıca enjekte edildi. Hastalar enjeksiyon esnasında gelişen komplikasyonlar. birinci ve üçüncü aydaki görme keskinlikleri. göziçi basınçları ve üveitik bulguları açısından değerlendirildiler.Sonuçlar : Tedavi kapsamında yaş ortalaması 29.3 ± 12.4 olan 15 hastanın 17 gözü değerlendirildi. Üveit etiolojisinde 6 (%40.0) hastada Behçet hastalığı. 3 (%20.0) hastada intermediyer üveit. bir (%6.7) hastada Vogt-Koyonagi-Harada Sendromu. bir (%6.7) hastada ankilozan spondilit. bir (%6.7) hastada dirençli iridosiklit ve 3 (%20.0) hastada etiolojisi belirlenemeyen posterior üveit saptandı. Başlangıç görme keskinliği Snellen eşelinde 0.49 ± 0.31 düzeyinden. uygulama sonrası birinci ayda 0.59 ± 0.32 ve üçüncü ayda ise 0.68 ± 0.37 düzeyindeydi (p=0.002). Aplanasyon tonometresi ile ölçülen göziçi basınç değerleri başlangıçta 14.6 ± 3.8 mmHg iken. enjeksiyon ardından birinci ayda 16.7 ± 6.0 ve üçüncü ayda 13.9 ± 3.6 mmHg olarak ölçüldü (p=0.07). İki hastada tedavi gerektiren göziçi basınç artışı oluştu. Bir hastada enjeksiyon anında epileptiform kasılmalar. bir hastada ise kesi yerinde enfeksiyon ile karşılaşıldı.Tartışma : Subtenon kanülle uygulanan posterior depo steroid enjeksiyonu. seçilmiş hasta grubunda sınırlı komplikasyon potansiyeli ile yüksek etkinlik gösterebilmektedir

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Cite This Article

KAYIKÇIOĞLU, Ö., ÇERÇİ, M. A., SEYMENOĞLU, G. (2022). Efficacy and complications of subtenon depo steroid injections in uveitic patients by subtenon canulla. Türk Oftalmoloji Dergisi, Cilt: 37 - Sayı: 1, 23–29. https://ajindex.com/articles/638616

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