Journals / Türk Oftalmoloji Dergisi / 2008 / Cilt: 38 - Sayı: 4

Penetrating keratoplasty for corneal stromal dystrophy

Kornea stroma distrofilerinde penetran keratoplasti

Pages
281–285
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Recurrence is infraquent in macular dystrophy.

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Objective & Hypothesis:PURPOSE: To assess the prognosis of penetrating keratoplasty in corneal stromal dystrophies.METHODS: Between January 1995 and December 2005, fifty seven eyes of 46 patients who received a corneal transplant for corneal stromal dystrophy were investigated retrospectively.
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Key Findings & Data:Data were analized with respect to graft clarity, complications, visual acuity and recurrence of dystrophy.RESULTS: The study population consisted of 9 eyes (15.8 %) with lattice dystrophy, 18 eyes (31.6 %) with granular dystrophy, 30 eyes (52.6 %) with macular dystrophy.
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Conclusion & Impact:Recurrence is infraquent in macular dystrophy.
🔬Design:Research Article
📍Scope:2005 Verileri
⚙️Variables:Domain Parameters

Abstract

PURPOSE: To assess the prognosis of penetrating keratoplasty in corneal stromal dystrophies.METHODS: Between January 1995 and December 2005, fifty seven eyes of 46 patients who received a corneal transplant for corneal stromal dystrophy were investigated retrospectively. Data were analized with respect to graft clarity, complications, visual acuity and recurrence of dystrophy.RESULTS: The study population consisted of 9 eyes (15.8 %) with lattice dystrophy, 18 eyes (31.6 %) with granular dystrophy, 30 eyes (52.6 %) with macular dystrophy. After a mean follow-up of 26,3 ± 19,6 (range; 6-98 ) months, the graft remained clear in 48 eyes (84.2 %). The most common factor for graft failure was recurrent dystrophy. There was a recurrence in 4 eyes (44.5%) with lattice, after a mean interval of 39.25 ± 5.56 (range; 33-46) months, and in 6 eyes (33.4 %) with granular dystrophy, after a mean interval of 36 ± 17.79 (range; 17-65) months. Two eyes (6.7 %) with macular dystrophy had a recurrence at 76 and 85 months. A clinically significant recurrence, defined as the biomicroscopic findings of recurrent disease located centrally within the graft with decreased two or more lines visual acuity, occurred in 5 eyes (5/6) with granular dystrophy and one eye (1/4) with lattice dystrophy. There wasn’t any clinically significant recurrence in eyes with macular dystrophy. A final refracted visual acuity of 20/100 or better was achieved in 43 eyes (75.4 %).CONCLUSIONS: The most important factor influencing the success of the penetrating keratoplasty was recurrent disease in granular and lattice dystrophy. Recurrence is infraquent in macular dystrophy.

Özet

AMAÇ: Kornea stroma distrofilerinde penetran keratoplasti prognozunu değerlendirmek.YÖNTEM: Ocak 1995-Aralık 2005 tarihleri arasında kornea stroma distrofisi için kornea transplantasyonu yapılan 46 olgunun 57 gözü retrospektif olarak incelendi. Veriler; greft canlılığı, komplikasyonlar, görme keskinliği ve distrofi nüksü açısından değerlendirildi.BULGULAR: Çalışma grubu lattis distrofili 9 göz (%15,8), granüler distrofili 18 göz (% 31,6) ve maküler distrofili 30 gözden (% 52,6) oluşmaktaydı. Ortalama 26,3 ± 19,6 ( ranj; 6-98 ) ay takip sonucunda 48 (% 84,2) gözde greft saydam kalmıştı. Greft başarısızlığı için en sık faktör hastalık nüksü idi. Lattis distrofili 4 gözde (% 44.5) ort. 39.25 ± 5.56 ( Ranj; 33-46) ay sonra, granüler distrofili 6 gözde (% 33.4) ort. 36 ± 17.79 ( ranj; 17-65) ay sonra nüks görüldü. Maküler distrofili iki gözde (% 6.7) 76 ve 85’ inci aylarda nüks vardı. İki sıra ve üzeri görme kaybı ile birlikte biyomikroskopik olarak greft santraline yerleşmiş hastalık tekrarı olarak belirlenen klinik önemli nüks, granüler distrofili beş gözde (5/6) ve lattis distrofili bir gözde (1/4) gelişti. Maküler distrofili gözlerde klinik önemli nüks yoktu. 0.2 ve üzeri sonuç görme keskinliği 43 gözde ( % 75,4) elde edildi.SONUÇ: Granüler ve lattis distrofisinde penetran keratoplasti başarısını etkileyen en önemli faktörün distrofi nüksü olduğu gözlenmiştir. Maküler distrofide rekürrens seyrektir.

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Cite This Article

ONAT, M., NURÖZLER, A. B., ÖZKAN, G., YILDIZ, E. Ç., KARAGÜZEL, H. T., BUDAK, K., ÖRNEK, F. (2022). Penetrating keratoplasty for corneal stromal dystrophy. Türk Oftalmoloji Dergisi, Cilt: 38 - Sayı: 4, 281–285. https://ajindex.com/articles/638592

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