Journals / Türk Oftalmoloji Dergisi / 2011 / Cilt: 41 - Sayı: 2

Toxic anterior segment syndrome: Clinical and histopathological findings

Toksik anterior segment sendromu: Klinik ve histopatolojik bulgular

Pages
73–77
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It is important that switching to disposable instruments and/or adequate cleaning of the surgical instruments will reduce the TASS complication.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To analyze the clinical and histopathological findings of toxic anterior segment syndrome (TASS) which can be developed after phacoemulsification surgery.
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Key Findings & Data:All patients were examined at the 1st, 12th, 24th, and 48th hours postoperatively.
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Conclusion & Impact:It is important that switching to disposable instruments and/or adequate cleaning of the surgical instruments will reduce the TASS complication.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To analyze the clinical and histopathological findings of toxic anterior segment syndrome (TASS) which can be developed after phacoemulsification surgery. Material and Method: We evaluated the cases of three patients who developed TASS after uneventful phacoemulsification operations performed by the same surgeon in the same session. All patients were examined at the 1st, 12th, 24th, and 48th hours postoperatively. Further follow-up visits were planned as needed. Corneal decompensation developed in all three cases. One patient underwent evisceration and another one - penetrating keratoplasty. Both corneas were analyzed histopathologically. Results: The patients were between 61 and 73 years of age and all were male. Blurred vision without pain, limbus-tolimbus corneal edema and hypopyon were observed in all three cases. In each case, the iris was irregularly dilated and atrophic. Histopathological evaluation showed that the endothelial cell layer has disappeared completely in two corneas. The third case suffered loss of vision due to corneal decompensation and glaucoma refractory to medical treatment. Discussion: TASS is a serious complication, which can result in complete loss of corneal endothelial layer. It is important that switching to disposable instruments and/or adequate cleaning of the surgical instruments will reduce the TASS complication.

Özet

Amaç: Fakoemulsifikasyon cerrahisi sonrasında gelişebilen toksik anterior segment sendromu (TASS) ‘nun klinik ve histopatolojik bulgularını analiz etmek. Gereç ve Yöntem: Aynı seansta aynı cerrah tarafından gerçekleştirilen sorunsuz fakoemulsifikasyon operasyonları sonrasında gelişen üç TASS olgusu değerlendirildi. Hastaların postoperatif 1., 12., 24., 48. saat kontrolleri yapıldı. Sonraki takipler ihtiyaca göre planlandı. Üç olguda da korneal dekompansasyon gelişti. Bir olguya eviserasyon diğerine ise penetran keratoplasti operasyonu uygulandı. Her iki korneanın histopatolojik analizi yapıldı. Sonuçlar: Hastalar 61 ve 73 yaş aralığında olup, hepsi erkekti. Tüm olgularda ağrısız bulanık görme, limbustan limbusa korneal ödem ve hipopiyon vardı. Her olguda iris düzensiz dilate ve atrofikti. İki korneanın histopatolojik incelemesi; endotel hücre tabakasının tamamen yok olduğunu gösterdi. Üçüncü olgu ise korneal dekompansasyon ve tedaviye dirençli glokom nedeniyle görmesini kaybetti. Tartışma: TASS kornea endotel tabakasının tamamen kaybıyla sonuçlanabilen ciddi bir komplikasyondur. Tek kullanımlık aletlere geçiş ve/veya aletlerin usule uygun yıkanması, TASS komplikasyonunu azaltmak için önem taşımaktadır. (Turk J Ophthalmol 2011; 41: 73-7)

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Cite This Article

MİDİ, A., AKINGÖL, Z., ARSLAN, O. Ş., ŞENCAN, S., TUNÇ, Z., ÜNAL, M. (2022). Toxic anterior segment syndrome: Clinical and histopathological findings. Türk Oftalmoloji Dergisi, Cilt: 41 - Sayı: 2, 73–77. https://ajindex.com/articles/638352

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