Journals / Türk Oftalmoloji Dergisi / 2012 / Cilt: 42 - Sayı: 2

Topiramate-induced myopic shift and bilateral secondary angle-closure glaucoma

Topiramat kullanımının tetiklediği miyopik kayma ve bilateral sekonder kapalı açılı glokom

Pages
154–156
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We recommend that particular attention should be paid in prescribing topiramate to patients who are already under treatment with duloxetine or other antidepressants with a similar mechanism of action and that patients should be informed about possible side effects. (Turk J Ophthalmol 2012; 42: 154-6)

📌 3 Key Takeaways

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Objective & Hypothesis:In this case report, we discuss a 24-year-old female patient with diagnosis of epilepsy who developed myopia and acute bilateral angleclosure glaucoma after 7 days of treatment with topiramate.
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Key Findings & Data:Both topiramate and duloxetine have been related to the increase of intraocular pressure and the development of glaucoma.
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Conclusion & Impact:We recommend that particular attention should be paid in prescribing topiramate to patients who are already under treatment with duloxetine or other antidepressants with a similar mechanism of action and that patients should be informed about possible side effects. (Turk J Ophthalmol 2012; 42: 154-6)
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

In this case report, we discuss a 24-year-old female patient with diagnosis of epilepsy who developed myopia and acute bilateral angleclosure glaucoma after 7 days of treatment with topiramate. The patient had also been taking duloxetine daily for six months with diagnosis of depression. Both topiramate and duloxetine have been related to the increase of intraocular pressure and the development of glaucoma. This case report highlights the need for being suspicious about acute bilateral angle-closure glaucoma, which is reversible by supportive treatment in patients using topiramate. We recommend that particular attention should be paid in prescribing topiramate to patients who are already under treatment with duloxetine or other antidepressants with a similar mechanism of action and that patients should be informed about possible side effects. (Turk J Ophthalmol 2012; 42: 154-6)

Özet

Bu olgu sunumunda epilepsi tanısı ile 7 günlük topiramat tedavisi sonrasında miyopik kayma ve akut bilateral kapalı açılı glokom gelişen 24 yaşında bayan hastayı tartıştık. Hasta aynı zamanda depresyon tedavisi nedeni ile 6 aydır duloksetin kullanmaktaydı. Hem topiramat hem de duloksetin artmış göz içi basıncı ve glokom gelişimi ile ilişkilidir. Bu olgu sunumu topiramat kullanan hastalarda, destekleyici tedavi ile geri dönüşümlü olan akut bilateral kapalı açılı glokom krizi konusunda şüpheci olunması gerektiğini vurgulamaktadır. Duloksetin ya da benzeri etki mekanizmasına sahip antidepresanları kullanmakta olan hastalara topiramat tedavisi başlarken bu konuda özellikle dikkatli olmayı ve olası yan etkiler açısından hastayı bilgilendirmeyi öneriyoruz. (Turk J Ophthalmol 2012; 42: 154-6)

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Cite This Article

ÖRÜM, Ö., TARAKÇIOĞLU, H., YİĞİT, U. (2022). Topiramate-induced myopic shift and bilateral secondary angle-closure glaucoma. Türk Oftalmoloji Dergisi, Cilt: 42 - Sayı: 2, 154–156. https://ajindex.com/articles/638318

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