Journals / Türk Oftalmoloji Dergisi / 2012 / Cilt: 42 - Sayı: 5

Psödoeksfoliasyon sendromu ve konjonktivaşalazisli olgularda oküler yüzey parametrelerinin değerlendirilmesi

Evaluation of the ocular surface parameters in pseudoexfoliation syndrome and conjunctivochalasis

Pages
332–335
Publication Date
2022-11-05
DOI
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It seems reasonable to evaluate and follow up PEX patients for CCh and ocular surface disease.. (Turk J Ophthalmol

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To evaluate the ocular surface parameters in pseudoexfoliative (PEX) patients with conjunctivochalasis (CCh).
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Key Findings & Data:Material and Method: Fifty-three eyes of 53 patients with PEX syndrome and 107 eyes of 107 subjects without PEX were enrolled in this study.
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Conclusion & Impact:It seems reasonable to evaluate and follow up PEX patients for CCh and ocular surface disease.. (Turk J Ophthalmol
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate the ocular surface parameters in pseudoexfoliative (PEX) patients with conjunctivochalasis (CCh). Material and Method: Fifty-three eyes of 53 patients with PEX syndrome and 107 eyes of 107 subjects without PEX were enrolled in this study. All subjects were categorized into two groups according to the presence or absence of CCh. The ocular surface characteristics were evaluated with standard tear break-up time testing (BUT), lissamine green (LG) staining of the conjunctiva and cornea, and Schirmer I test with topical anesthesia. Patients were also assessed with the Ocular Surface Disease Index (OSDI) questionnaire with respect to the severity of their subjective symptoms. The Mann-Whitney U-test, student s t-test, and logistic regression analysis were used for statistical evaluations. Results: Among the 160 subjects, 30 (56.6%) in the PEX group and 38 (35.5%) in the control group had CCh (p=0.018). Logistic regression adjusted to gender and age showed that eyes with PEX were 2.3 times (odds ratio, 95% CI: 1.1 to 4.6) more likely to develop CCh than eyes without PEX (p=0.015). There were significant differences in the BUT scores, Schirmer values, LG staining scores and the OSDI scores of patients who had PEX and those without PEX. Discussion: The frequency of CCh is significantly higher in patients with PEX syndrome. Both PEX and CCh affect the ocular surface test results. It seems reasonable to evaluate and follow up PEX patients for CCh and ocular surface disease.. (Turk J Ophthalmol

Özet

Amaç: Psödoeksfoliasyon sendromu ve konjonktivaşalazisi olan hastalarda oküler yüzey parametrelerinin değerlendirilmesi. Gereç ve Yöntem: Psödoeksfoliasyon sendromu olan 53 hastanın 53 gözü ve psödoeksfoliasyonu olmayan 107 hastanın 107 gözü çalışmaya dahil edildi. Tüm hastalar konjonktivaşalazisin varlığına göre iki alt gruba ayrıldı. Oküler yüzey parametreleri göz yaşkırılma zamanı testi (BUT), topikal anestezi ile Schirmer testi ve lissamin yeşili (LG) ile kornea ve konjonktiva boyanması ildeğerlendirildi. Ayrıca, semptomların şiddetinin değerlendirilmesi amacıyla hastalara oküler yüzey hastalık indeks (OSDI) skorlamasuygulandı. İstatistiksel analizde Mann-Whitney U testi, Student-t testi ve lojistik regresyon analizi kullanıldı. Sonuçlar: Değerlendirmeye alınan 160 hastada, psödoeksfoliasyon sendromu bulunan hastaların 30unda (%56,6), kontrol grubunun 38inde (%35,5) konjonktivaşalazis saptandı (p=0,018). Lojistik regresyon analizinde yaş ve cinsiyet düzeltmesi yapıldığındakonjonktivaşalazis sıklığının psödoeksfoliasyonu olanlarda olmayanlara göre 2.3 kat (odds oranı, %95 CI: 1.1 to 4,6) daha fazla olduğu görüldü (p=0,015). Psödoeksfoliasyonu olan hastalar ile kontrol grubu arasında BUT skorları, Schirmer testi değerleri, LG boyanmasve OSDI skorları arasında istatistiksel olarak anlamlı fark saptandı. Tart flma: Konjonktivaşalazis sıklığı psödoeksfoliasyon sendromlu hastalarda daha fazla görülmektedir. Hem psödoeksfoliasyon varlığhem de konjonktivaşalazis oküler yüzey parametrelerini etkilemektedir. Psödoeksfoliasyon sendromlu olgular konjonktivaşalazis ve oküleyüzey hastalığı varlığı açısından değerlendirilmeli ve takipleri yapılmalıdır. (Turk J Ophthalmol 2012; 42: 332-5)

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Cite This Article

KOCABEYOĞLU, S., ORHAN, M., İRKEÇ, M., MOCAN, M. C. (2022). Psödoeksfoliasyon sendromu ve konjonktivaşalazisli olgularda oküler yüzey parametrelerinin değerlendirilmesi. Türk Oftalmoloji Dergisi, Cilt: 42 - Sayı: 5, 332–335. https://ajindex.com/articles/638270

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