Journals / Türk Oftalmoloji Dergisi / 2013 / Cilt: 43 - Sayı: 2

Fundus autofluorescence in acute and chronic central serous chorioretinopathy

Akut ve kronik santral seröz koryoretinopatide fundus otofloresansı

Pages
94–98
Publication Date
2022-11-05
DOI
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Discussion: Subretinal deposits are detected mostly in chronic CSC and are observed as hyperautofluorescence on FAF imaging.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To evaluate the findings of fundus autofluorescence (FAF) imaging in acute and chronic central serous chorioretinopathy (CSC) patients.
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Key Findings & Data:Material and Method: A total of 40 eyes of 36 patients (8 females, 28 males) were analyzed retrospectively.
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Conclusion & Impact:Discussion: Subretinal deposits are detected mostly in chronic CSC and are observed as hyperautofluorescence on FAF imaging.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate the findings of fundus autofluorescence (FAF) imaging in acute and chronic central serous chorioretinopathy (CSC) patients. Material and Method: A total of 40 eyes of 36 patients (8 females, 28 males) were analyzed retrospectively. The patients were divided into two groups as acute CSC when the complaints lasted less than six months and as chronic CSC for complaints of more than six months’ duration. Complete ophthalmologic examination was performed. Retinal thickness, pigment epithelium detachment (PED), and subretinal deposits were analyzed using OCT. Leakage points and serous retinal detachment were classified as hypoautofluorescence or hyperautofluorescence on FAF imaging. Results: The number of eyes with acute CSC was 21 (52.5%), and the number of eyes with chronic CSC was 19 (47.5%). The average retinal thickness was 422.14±99.6 microns in acute CSC eyes and 383.6±104.1 microns in chronic CSC eyes (p=0.240). We detected PED in 11 eyes and subretinal deposits in 21 eyes. The leakage points of all eyes showed hyperfluorescence in FFA. On FAF imaging, 33 leakage points demonstrated hypoautofluorescence and 7 leakage points showed hyperautofluorescence. The areas of serous retinal detachment were observed as hypoautofluorescence in 22 eyes and as hyperautofluorescence in 18 eyes. Discussion: Subretinal deposits are detected mostly in chronic CSC and are observed as hyperautofluorescence on FAF imaging.

Özet

Amaç: Akut ve kronik santral seröz koryoretinopati (SSKR) hastalarında, fundus otofloresansı (FOF) bulgularını değerlendirmek. Gereç ve Yöntem: Sekiz kadın, 28 erkek toplam 36 hastanın 40 gözü retrospektif olarak incelendi. Yakınmaları 6 aydan kısa süreli olan gözler akut SSKR, 6 aydan uzun süren gözlerse kronik SSKR olarak iki gruba ayrıldı. Hastalara tam oftalmolojik muayene yapıldı. OKT’de retina kalınlığına, pigment epitel dekolmanına (PED) ve subretinal depozitlere bakıldı. Sızıntı noktaları ve seröz retina dekolmanı alanları FOF görüntülemede hipootofloresans veya hiperotofloresans olarak sınıflandırıldı. Sonuçlar: Akut SSKR’li gözlerin sayısı 21 (%52,5), kronik SSKR’li gözlerin sayısıysa 19 (%47,5) idi. Ortalama retina kalınlığı akut SSKR’li gözlerde 422,14±99,6 mikron, kronik SSKR’li gözlerde 383,6±104,1 mikron ölçüldü (p=0,240). PED 11 gözde, subretinal depozitler 21 gözde saptandı. FFA’da sızıntı noktaları tüm gözlerde hiperfloresans izlendi. FOF görüntülemede sızıntı noktalarının 33 tanesi hipootofloresans, 7 tanesi hiperotofloresans izlendi. Seröz retina dekolmanı alanlarıysa gözlerin 22’sinde hipootofloresans, 18’inde hiperotofloresans izlendi. Tartışma: FOF, akut ve kronik SSKR hastalığının tanı ve takibinde kullanılabilecek yararlı bir görüntüleme yöntemidir. Subretinal depozitler daha çok kronik SSKR’li gözlerde saptanmakta ve FOF görüntülemede hiperotofloresans görülmektedir.

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Cite This Article

ÖZDEMİR, Ö., SÖĞÜTLÜ, E. S., KARAÇOR, A., EROL, M. K., BULUT, M., TURGUT, D. Ç. (2022). Fundus autofluorescence in acute and chronic central serous chorioretinopathy. Türk Oftalmoloji Dergisi, Cilt: 43 - Sayı: 2, 94–98. https://ajindex.com/articles/638222

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References (1)

  1. Von Graefe A. Über zentrale rezidivierende retinitis. Arch Opthalmol. 1866;12:211-5. 2. Gass JDM. Stereoscopic Atlas of Macular Diseases: Diagnosis and Treatment. (4th ed). St. Louis; Mosby Inc; 1997:52-70. 3. Guyer DR, Gragoudas ES. Central serous chorioretinopathy. In: Albert DM, Jakobiec FA, eds. Principles and practice of ophthalmology. Philadelphia; WB Saunders Co.; 1994:2:818-25. 4. Bennet G. Central serous retinopathy. Br J Ophthalmol. 1955;39:605-18. 5. Gass JDM. Pathogenesis of disciform detachment of the neuroepithelium, idiopathic central serous choroidopathy. Am J Ophthalmol. 1967;63:587-615. 6. Jalkh AE, Jabbour N, Avila MP Trempe CL, Schepens CL. Retinal pigment, epithelium decompensation. I. Clinical features and natural course. Ophthalmology. 1984;91:12:1544–8. 7. Sekiryu T, Iida T, Maruko I, Saito K and Kondo T. Infrared fundus autofluorescence and central serous chorioretinopathy. Invest Ophtolmol Vis Sci. 2010;51:4956-62. 8. Piccolino FC, Eandi CM, Ventre L et al. Photodynamic therapy for chronic central serous chorioretinopathy. Retina. 2003;23:752-63. 9. Guyer DR, Yannuzzi LA, Slakter JS, Sorenson JA, Ho A, Orlock D. Digital indocyanine green videoangiography of central serous chorioretinopathy. Arch Ophthalmol. 1994;112:1057–62. 10. Piccolino FC, Borgia L, Zinicola E, Zingirian M. Indocyanine green angiographic findings in central serous chorioretinopathy. Eye. 1995;9:324-32. 11. Iida T, Kishi S, Hagimura N, Shimizu K. Persistent and bilateral choroidal vascular abnormalities in central serous chorioretinopathy. Retina. 1999;19:508-12. 12. Hee MR, Puliafito CA, Wong C et al. Optical coherence tomography of central serous chorioretinopathy. Am J Ophthalmol. 1995;120:65-74. 13. Wang M, Sander B, Lund-Andersen H and Larsen M. Detection of shallow detachments in central serous chorioretinopathy. Acta Ophthalmologica Scandinavica. 1999;77:402-5. 14. Delori FC, Dorey CK, Staurenghi G, Arend O, Goger DG and Weiter JJ. In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics. Invest Ophtolmol Vis Sci. 1995;36:718–29. 15. Von Rückmann A, Fitzke FW Bird AC. Distribution of fundus, autofluorescence with a scanning laser ophthalmoscope. Br J Ophthalmol. 1995;79:407-12. 16. Von Rückmann A, Fitzke FW Fan J, Halfyard A, Bird AC. Abnormalities of, fundus autofluorescence in central serous retinopathy. Am J Ophthalmol. 2002;133:780-6. 17. Dinc UA, Tatlipinar S, Yenerel M, Görgün E, Ciftci F. Fundus