Journals / Türk Oftalmoloji Dergisi / 2014 / Cilt: 44 - Sayı: 5

Chloroquine retinopathy without bull s eye maculopathy

Öküz gözü makulopatisi görünümü olmayan ciddi klorokin retinopatisi

Pages
403–406
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Besides clinical evaluation, the patient was assessed with different functional (visual field, microperimetry, electroretinography, multifocal electroretinography) and structural (optical coherence tomography, retinal nerve fiber layer thickness analysis) retinal analysis methods. (Turk J Ophthalmol 2014; 44: 403-6)

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Chloroquine has long been used for the treatment of autoimmune diseases, beside its use for treatment and prevention of malaria.
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Key Findings & Data:We herein report a chloroquine retinopathy case with a history of 250 mg per day chloroquine treatment for SLE for the last 15 years.
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Conclusion & Impact:Besides clinical evaluation, the patient was assessed with different functional (visual field, microperimetry, electroretinography, multifocal electroretinography) and structural (optical coherence tomography, retinal nerve fiber layer thickness analysis) retinal analysis methods. (Turk J Ophthalmol 2014; 44: 403-6)
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Abstract

Chloroquine has long been used for the treatment of autoimmune diseases, beside its use for treatment and prevention of malaria. We herein report a chloroquine retinopathy case with a history of 250 mg per day chloroquine treatment for SLE for the last 15 years. Besides clinical evaluation, the patient was assessed with different functional (visual field, microperimetry, electroretinography, multifocal electroretinography) and structural (optical coherence tomography, retinal nerve fiber layer thickness analysis) retinal analysis methods. (Turk J Ophthalmol 2014; 44: 403-6)

Özet

Klorokin uzun zamandır malaryanın tedavi ve önlenmesi için kullanılmasının yanında otoimmün hastalıkların tedavisinde de kullanılmaktadır. Makalede 15 yıldır sistemik lupus eritematozus tanısıyla günlük 250 mg dozunda klorokin tedavisi kullanan bir olguda gelişen klorokin retinopatisi sunulmuştur. Olgu, klinik bulguların yanı sıra, çeşitli fonksiyonel (görme alanı, mikroperimetri, elektroretinografi, multifokal elektroretinografi) ve yapısal (optik koherens tomografi, retina sinir lifi tabakası kalınlığı analizi) retinal analiz yöntemleriyle değerlendirilmiştir. (Turk J Ophthalmol 2014; 44: 403-6)

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Cite This Article

GÖKÇE, G., ÖZGÖNÜL, C., KÜÇÜKEVCİLOĞLU, M., SOBACI, G. (2022). Chloroquine retinopathy without bull s eye maculopathy. Türk Oftalmoloji Dergisi, Cilt: 44 - Sayı: 5, 403–406. https://ajindex.com/articles/638073

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References (14)

  1. Hobbs HE, Sorsby A, Freedman A. Retinopathy following chloroquine therapy. Lancet. 1959;2:478-80.
  2. Tığ UŞ, Bardak Y, Çekiç O, Yıldız AA, Tunç E, Şahin M. Sistemik hidroksiklorokin kullanımı ve erken evre maküla fonksiyon değişimleri. Ret- Vit. 2007;15:111-4.
  3. Marmor MF, Kellner U, Lai TY, Lyons JS, Mieler WF; American Academy of Ophthalmology. Revised recommendations on screening for chloroquine and hydroxychloroquine retinopathy. Ophthalmology. 2011;118: 415-22.
  4. Kellner U, Kraus H, Foerster MH. Multifocal ERG in chloroquine retinopathy: regional variance of retinal dysfunction. Graefes Arch Clin Exp Ophthalmol. 2000;238:94-7.
  5. Angi M, Romano V, Valldeperas X, Romano F, Romano MR. Macular sensitivity changes for detection of chloroquine toxicity in asymptomatic patient. Int Ophthalmol. 2010;30:195-7.
  6. Demir S, Süllü Y. Klorokin retinopatisi. MN Oftalmoloji. 2009;16:194-8.
  7. Yenice Ö, Kazokoğlu H, Cerman E. Hidroksiklorokin retinopatisi. T Klin Oftalmoloji. 2004;13:45-8.
  8. Marmor MF, Zrenner E. Standard for clinical electroretinography (1999 update). International Society for Clinical Electrophysiology of Vision. Doc Ophthalmol. 1998;97:143-56.
  9. Gilbert ME, Savino PJ. Missing the bull’s eye. Surv Ophthalmol. 2007;52:440-2.
  10. Rosenthal AR, Kolb H, Bergsma D, Huxsoll D, Hopkins JL. Chloroquine retinopathy in the rhesus monkey. Invest Ophthalmol Vis Sci. 1978;17:1158-75.
  11. Rodriguez-Padilla JA, Hedges TR 3rd, Monson B, et al. High-speed ultra- high-resolution optical coherence tomography findings in hydroxychloroquine retinopathy. Arch Ophthalmol. 2007;125:775-80.
  12. Easterbrook M, Trope G. Value of Humphrey perimetry in the detection of early chloroquine retinopathy. Lens Eye Toxic Res. 1989;6:255-68.
  13. Bonanomi MT, Dantas NC, Medeiros FA. Retinal nerve fibre layer thickness measurements in patients using chloroquine. Clin Experiment Ophthalmol. 2006; 34:130-6.
  14. Ma X, Yan L, He L, He D, Lu H. Ocular fundus manifestation of two patients following long-term chloroquine therapy: a case report. Diagn Pathol. 2010;5:20.