SavedAdd your journal

Journals / Türk Oftalmoloji Dergisi / 2015 / Cilt: 45 - Sayı: 4

Evaluation of Filtering Bleb Function after Trabeculectomy with Mitomycin C Using Biomicroscopy, Anterior Segment Optical Coherence Tomography and In Vivo Confocal Microscopy

Mitomisin C ile Trabekülektomi Uygulanmış Olgularda Filtran Bleb Fonksiyonunun Biyomikroskop, Ön Segment Optik Koherens Tomografi ve İn Vivo Konfokal Mikroskop ile Değerlendirilmesi

Cumali DEĞİRMENCİ
Suzan Güven YILMAZ
Ayşe YAĞCI
Melis PALAMAR
Pages
132–137
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In the comparison of non-functional and functional blebs,functional blebs were found to be superior in terms of biometric parameters on AS-OCT assessment (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: To analyze and assess compatibility of trabeculectomy filtering bleb characteristics and appearances using biomicroscopy,anterior segment optical coherence tomography (AS-OCT) and in vivo confocal microscopy (IVCM).Materials and Methods: Twenty-eight eyes of 28 patients who underwent glaucoma filtering surgery with mitomycin C in our clinicbetween 2009 and 2013 were evaluated.
📊
Key Findings & Data:The relation between biomicroscopic morphologicalstaging and bleb characteristics detected on AS-OCT and IVCM were assessed.Results: The mean age of the 28 patients (16 male, 12 female) was 57.2±15.9 (19 to 79) years.
💡
Conclusion & Impact:In the comparison of non-functional and functional blebs,functional blebs were found to be superior in terms of biometric parameters on AS-OCT assessment (p
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: To analyze and assess compatibility of trabeculectomy filtering bleb characteristics and appearances using biomicroscopy,anterior segment optical coherence tomography (AS-OCT) and in vivo confocal microscopy (IVCM).Materials and Methods: Twenty-eight eyes of 28 patients who underwent glaucoma filtering surgery with mitomycin C in our clinicbetween 2009 and 2013 were evaluated. Morphological appearances of the blebs on slit-lamp biomicroscopy were defined according tothe Moorfields bleb classification system. For the internal tissue assessment of blebs, AS-OCT and IVCM were performed. Bleb biometricparameters such as length, height and bleb wall thickness were assessed by AS-OCT; conjunctival epithelial-stromal cyst, structuralnetwork of conjunctival stroma and vascularisation were examined with IVCM. The relation between biomicroscopic morphologicalstaging and bleb characteristics detected on AS-OCT and IVCM were assessed.Results: The mean age of the 28 patients (16 male, 12 female) was 57.2±15.9 (19 to 79) years. The mean time elapsed between surgeryand examination was 29.2±19.2 (6 to 68) months. According to biomicroscopic appearance, 17 (60.7%) blebs were functional (13 diffuse, 4microcystic), whereas 11 (39.3%) blebs were non-functional (9 flat, 2 encapsulated). In the comparison of non-functional and functional blebs,functional blebs were found to be superior in terms of biometric parameters on AS-OCT assessment (p

Özet

Amaç: Trabekülektomi bleblerinin özellik ve görünümlerinin biyomikroskop, ön segment optik koherens tomografi (ÖS-OKT) ve in vivo konfokal mikroskopi (İVKM) ile incelenerek birbiriyle uyumluluklarının değerlendirilmesi.Gereç ve Yöntem: Kliniğimizde 2009 ile 2013 tarihleri arasında Mitomisin C ile trabekülektomi cerrahisi geçirmiş 28 hastanın 28 gözü değerlendirildi. Bleblerin morfolojik görünümü, yarıklı lamba biyomikroskobu ile Moorfields Bleb Sınıflaması'na göre belirlendi. Bleb iç yapısını değerlendirmek üzere ÖS-OKT ve İVKM yapıldı. ÖS-OKT'de uzunluk, yükseklik ve bleb duvar kalınlığı gibi blebe ait biyometrik parametreler, İVKM'de konjonktivada epitelyal-stromal kist varlığı, konjonktiva stromasının ağ yapısı ve damarlanması incelendi. Biyomikroskopik olarak yapılan morfolojik sınıflama ile ÖS-OKT ve İVKM'de saptanan yapısal bleb özellikleri arasındaki ilişki değerlendirildi.Bulgular: Çalışmaya alınan 28 hastanın (16 erkek, 12 kadın) yaş ortalaması 57,2±15,9 yıl idi. Olgular cerrahi sonrası ortalama 29,2±19,2 ay izlendi. Biyomikroskopik görünümlerine göre bleblerin 17'sinin (%60,7) fonksiyonel (13 diffüz, 4 mikrokistik), 11'inin (%39,3) ise fonksiyonel olmadığı (9 silik, 2 enkapsüle) belirlendi. ÖS-OKT ile yapılan değerlendirmede; fonksiyonel blebler, fonksiyonel olmayanlara göre bleb biyometrik parametreler açısından üstün bulundu (p

🔖

Cite This Article

DEĞİRMENCİ, C., YILMAZ, S. G., YAĞCI, A., PALAMAR, M. (2022). Evaluation of Filtering Bleb Function after Trabeculectomy with Mitomycin C Using Biomicroscopy, Anterior Segment Optical Coherence Tomography and In Vivo Confocal Microscopy. Türk Oftalmoloji Dergisi, Cilt: 45 - Sayı: 4, 132–137. https://ajindex.com/articles/637955

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Cairns JE. Trabeculectomy, Preliminary report of a new method. Am J Ophthalmol. 1968;66:673-679
  2. Funk J, Frank A. How can the success of a glaucoma operation be predicted? Ophthalmologe. 1996;93:592-595
  3. Marquardt D, Lieb WE, Grehn F. Intensified postoperative care versus conventional follow-up: a retrospective long-term analysis of 177 trabeculectomies. Graefes Arch Clin Exp Ophthalmol. 2004;242:106-113
  4. Palmer SS. Mitomycin as adjunct chemotherapy with trabeculectomy. Ophthalmology. 1991;98:317-321
  5. Wells AP, Crowston JG, Marks J, Kirwan JF, Smith G, Clarke JC, Shah R, Vieira J, Bunce C, Murdoch I, Khaw PT. A pilot study of a system for grading of drainage bleb safter glaucoma surgery. J Glaucoma. 2004;13:454-460
  6. Vesti E. Filtering blebs: followup of trabeculectomy. Ophthalmic Surg. 1993;24:249-255
  7. Zhanh Y, Wu Q, Zhang M, Song BW, DU XH, Lu B. Evaluating subconjunctival bleb function after trabeculectomy using slit-lamp optical coherence tomography and ultrasound biomicroscopy. Chin Med J. 2008;121:1274-1279
  8. Ciancaglini M, Carpineto P, Agnifili L, Nubile M, Lanzini M, Fasanella V, Mastropasqua L. Filtering bleb functionality: a clinical, anterior segment optical coherence tomography and in vivo confocal microscopy study. J Glaucoma. 2008;17:308-317
  9. Wells AP, Crowston JG, Marks J, Kirwan JF, Smith G, Clarke JC, Shah R, Vieira J, Bunce C, Murdoch I, Khaw PT. A pilot study of a system for grading of drainage blebs after glaucoma surgery. J Glaucoma. 2004;13:454-460
  10. Messmer EM, Zapp DM, Mackert MJ, Thiel M, Kampik A. In vivo confocal microscopy of filtering blebs after trabeculectomy. Arch Ophthalmol. 2006;124:1095-1103
  11. Labbe´ A, Dupas B, Hamard P, Baudouin C. In vivo confocal microscopy study of blebs after filtering surgery. Ophthalmology. 2005;112:1979
  12. Guthoff R, Klink T, Schlunck G, Grehn F. In vivo confocal microscopy of failing and functioning filtering blebs: Results and clinical correlations. J Glaucoma. 2006;15:552-558
  13. Wells A, Ashraff N, Hall R, Purdie G. Comparison of two clinical bleb grading systems. Ophthalmology. 2006;113:77-83
  14. Picht G, Grehn F. Classification of filtering in trabeculectomy: biomicroscopy and functionality. Curr Opin Ophthalmol. 1998;9:2-8
  15. Cantor LB, Mantravadi A, WuDunn D, Swamynathan K, Cortes A. Morphologic classification of filtering blebs after glaucoma filtration surgery: the Indiana Bleb Appearance Grading Scale. J Glaucoma. 2003;12:266-271
  16. Sbeity Z, Palm