Journals / Türk Oftalmoloji Dergisi / 2017 / Cilt: 47 - Sayı: 1

Retina and Optic Disc Characteristics in Amblyopic and Non-amblyopic Eyes of Patients with Myopic or Hyperopic Anisometropia

Miyopik veya Hipermetropik Anizometropili Hastaların Ambliyopik Olan ve Ambliyopik Olmayan Gözlerinin Retina ve Optik Disk Özellikleri

Pages
28–33
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further studies with more patients, including postmortem studies, may clarify the retinal, histopathologic, and anatomic differences between amblyopic and non- amblyopic eyes.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: To compare retinal and optic disc characteristics between amblyopic and non-amblyopic eyes in patients with myopic and hyperopic anisometropia measured with optical coherence tomography (OCT).
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Key Findings & Data:Materials and Methods: Patients with myopic (25 patients: 17 female, 8 male; median age 27 years, range 16-40 years) and hyperopic (31 patients: 19 female, 12 male; median age 20 years, range 13-41 years) anisometropic amblyopia were included.
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Conclusion & Impact:Further studies with more patients, including postmortem studies, may clarify the retinal, histopathologic, and anatomic differences between amblyopic and non- amblyopic eyes.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: To compare retinal and optic disc characteristics between amblyopic and non-amblyopic eyes in patients with myopic and hyperopic anisometropia measured with optical coherence tomography (OCT). Materials and Methods: Patients with myopic (25 patients: 17 female, 8 male; median age 27 years, range 16-40 years) and hyperopic (31 patients: 19 female, 12 male; median age 20 years, range 13-41 years) anisometropic amblyopia were included. Eye examination included determination of best-corrected visual acuity (BCVA) with a Snellen chart, measurement of manifest and cycloplegic refraction after pupillary dilation, alternate cover testing, globe movement evaluation, A-scan biometry for axial length, biomicroscopy, fundus examination, and OCT scanning. Main outcome measures were spherical equivalence, BCVA, axial length, retinal nerve fiber layer (RNFL) thickness, macular thickness, macular volume, and optic disc area. Results: In both myopic and hyperopic patients, the absolute value of the mean spherical equivalence was significantly greater in the amblyopic than non-amblyopic eyes, and the mean BCVA was significantly less in the amblyopic than the non-amblyopic eyes. In both myopic and hyperopic patients, there were no significant differences in mean RNFL thickness, macular thickness, macular volume, axial length, or optic disc area between amblyopic and non-amblyopic eyes. Conclusion: The amblyopic process may have no significant effect on the RNFL, macula, or optic disc. Further studies with more patients, including postmortem studies, may clarify the retinal, histopathologic, and anatomic differences between amblyopic and non- amblyopic eyes.

Özet

Amaç: Miyopik ve hipermetropik anizometropisi olan hastaların ambliyopik olan ve ambliyopik olmayan gözlerinin optik koherenstomografi (OKT) ile ölçülen retina ve optik disk özelliklerini karşılaştırmak.Gereç ve Yöntem: Miyopik (25 hasta: 17 kadın, 8 erkek), (yaş: ortanca 27 yaş; 16-40 yaş arasında) ve hipermetropik (31 hasta: 19kadın, 12 erkek), (yaş: ortanca, 20 yaş; 13-41 yaş arasında) anizometropik ambliyopisi olan hastalar çalışmaya katıldı. Göz muayenesinde,Snellen tablosu ile en iyi düzeltilmiş görme keskinliği (EİDGK), manifest ve pupiller dilatasyon sonrası ölçülen sikloplejik refraksiyon,alterne kapama testi, glob hareketi muayenesi, A-scan biyometri ile aksiyel uzunluk, biyomikroskopi, fundus muayenesi ve OKT ölçümüyapıldı. Ana sonuç ölçütleri, sferik eşdeğer, EİDGK, aksiyel uzunluk, retina sinir lifi tabakası (RSLT) kalınlığı, maküler kalınlık, makülerhacim ve optik disk alanı ölçümleri idi.Bulgular: Hem miyop hem de hipermetrop hastalarda ortalama sferik eşdeğerin mutlak değeri, ambliyopik gözlerde, ambliyopikolmayan gözlere göre daha yüksekti ve ortalama EDGK ambliyopik gözlerde ambliyopik olmayan gözlere göre daha düşüktü. Hemmiyopik hem de hipermetropik hastalarda, ambliyopik olan ve olmayan gözler arasında, ortalama RSLT kalınlığı, maküler kalınlık,maküler hacim, aksiyel uzunluk ve optik disk alanları açısından anlamlı fark bulunamadı.Sonuç: Ambliyopik sürecin, RSLT, maküla veya optik disk üzerinde belirgin bir etkisi olmayabilir. Daha fazla sayıda hasta ile,postmortem çalışmaları da içeren ileri çalışmaların yapılması, ambliyopik olan ve olmayan gözler arasındaki retinal, histopatolojik veanatomik farkları ortaya koyabilecektir.

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Cite This Article

ÇÖMEZ, A. T., EKİM, Y., ULU, E. Ş. (2022). Retina and Optic Disc Characteristics in Amblyopic and Non-amblyopic Eyes of Patients with Myopic or Hyperopic Anisometropia. Türk Oftalmoloji Dergisi, Cilt: 47 - Sayı: 1, 28–33. https://ajindex.com/articles/637861

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