Journals / Türk Oftalmoloji Dergisi / 2020 / Cilt: 50 - Sayı: 1

Efficacy of Topical Brinzolamide Treatment in Posterior MicrophthalmosRelated Macular Cystoid Lesions: A Case Series

Posterior Mikroftalmi İlişkili Maküler Kistoid Lezyonların Tedavisinde Topikal Brinzolamidin Etkinliği: Bir Olgu Serisi

Pages
44–49
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Topical brinzolamide treatment may have some positive effects on macular cystoid lesions in selected cases

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of this study was to report the outcome of topical brinzolamide 1% treatment on macular cystoid lesions resembling retinoschisis in 4 patients diagnosed with posterior microphthalmia.
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Key Findings & Data:The medical records of 4 patients with a clinical diagnosis of posterior microphthalmia who had started topical brinzolamide 1% treatment were reviewed.
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Conclusion & Impact:Topical brinzolamide treatment may have some positive effects on macular cystoid lesions in selected cases
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The aim of this study was to report the outcome of topical brinzolamide 1% treatment on macular cystoid lesions resembling retinoschisis in 4 patients diagnosed with posterior microphthalmia. The medical records of 4 patients with a clinical diagnosis of posterior microphthalmia who had started topical brinzolamide 1% treatment were reviewed. Visual acuity, central foveal thickness, and cystoid lesion area percentage were used to evaluate treatment response. In the follow-up, there was a decrease in central foveal thicknesses and cystoid lesion area percentages in both eyes of 3 of the patients. However, 1 patient showed increases in both parameters. Visual acuity remained stable in 5 eyes and increased in 3 eyes. Topical brinzolamide treatment may have some positive effects on macular cystoid lesions in selected cases

Özet

Posterior mikroftalmi (PM) tanılı dört hastada, topikal %1’lik brinzolamidin retinoskizise benzeyen maküler kistoid lezyonlar üzerindeki etkisini bildirmek. PM ilişkili foveoskizis tanısı ile topikal %1’lik brinzolamid tedavisi başlanan dört hastanın medikal kayıtları incelendi. Görme keskinliği, santral maküla kalınlığı ve kistoid lezyon alanı oranı tedavi yanıtını değerlendirmek için kullanıldı.Hastaların üçünde, her iki gözde de izlemde santral maküla kalınlığı ve kistoid lezyon alanı oranında düşüş izlendi. Ancak bir hastanın her iki gözünde iki parametrede de artış mevcuttu. Görme keskinliği beş gözde stabil kalırken, üç gözde artış mevcuttu. Topikal brinzolamid tedavisi, seçilmiş olgularda maküler kistoid lezyonların tedavisinde etkili olabilir.

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Cite This Article

SELVER, A., ENGİN, C. D., EKİNCİ, U. B., SAATÇİ, A. O. (2022). Efficacy of Topical Brinzolamide Treatment in Posterior MicrophthalmosRelated Macular Cystoid Lesions: A Case Series. Türk Oftalmoloji Dergisi, Cilt: 50 - Sayı: 1, 44–49. https://ajindex.com/articles/637828

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