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Journals / Türk Oftalmoloji Dergisi / 2020 / Cilt: 50 - Sayı: 4

Evaluation of Retinal Ganglion Cell Layer Thickness in the Early Period After Femtosecond LASIK Surgery

Femtosaniye Lazer Destekli LASIK Cerrahisi Sonrası Erken Dönemde Retinal Ganglion Hücre Tabakası Kalınlığının Değerlendirilmesi

Kemal ÖZÜLKEN
Çağrı İLHAN
Pages
211–215
Publication Date
2022-11-06
DOI
—
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Conclusion: There were no changes in GCT, NFT, and CMT values evaluated with SD-OCT in the early period after femtosecond LASIK surgery.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: To evaluate the early effects of femtosecond laser-assisted in situ keratomileusis (LASIK) surgery on retinal ganglion cell thickness (GCT), peripapillary retinal nerve fiber thickness (NFT), and central macular thickness (CMT) obtained by spectral domain optical coherence tomography (SD-OCT) in a healthy population.
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Key Findings & Data:Materials and Methods: This case-control study included data from the right eye of 40 subjects without any disease other than refractive error and who had undergone femtosecond LASIK surgery.
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Conclusion & Impact:Conclusion: There were no changes in GCT, NFT, and CMT values evaluated with SD-OCT in the early period after femtosecond LASIK surgery.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: To evaluate the early effects of femtosecond laser-assisted in situ keratomileusis (LASIK) surgery on retinal ganglion cell thickness (GCT), peripapillary retinal nerve fiber thickness (NFT), and central macular thickness (CMT) obtained by spectral domain optical coherence tomography (SD-OCT) in a healthy population. Materials and Methods: This case-control study included data from the right eye of 40 subjects without any disease other than refractive error and who had undergone femtosecond LASIK surgery. The preoperative, postoperative 1-hour, and postoperative 3-week GCT, NFT, and CMT values obtained by SD-OCT were compared. Results: The mean age was 27.54±5.99 years (18-45 years). GCT, NFT, and CMT were 18.43±6.03 μm, 107.90±9.01, and 234.3±21.2 μm preoperatively; 18.05±5.93 μm, 108.08±8.92 μm, and 230.1±22.6 μm at postoperative 1 hour; and 17.86±5.27 μm, 107.98±10.13, and 236.3±25.1 μm at postoperative 3 weeks (p=0.159, 0.85, and 0.254, respectively). Conclusion: There were no changes in GCT, NFT, and CMT values evaluated with SD-OCT in the early period after femtosecond LASIK surgery.

Özet

Amaç: Femtosaniye lazer destekli in situ keratomilozis (LASIK) cerrahisinin, sağlıklı örneklem grubunda uygulanması sonrası erken dönemde, spektral domain optik koherens tomografi (SD-OKT) ile elde edilen retinal ganglion hücre kalınlığı (GHK), peripapiller retina sinir lifi kalınlığı (SLK) ve santral maküla kalınlığı (SMK) üzerine olan etkilerinin incelenmesidir.Gereç ve Yöntem: Olgu kontrol çalışmasına femtosaniye LASIK cerrahisi uygulanan, kırma kusuru dışında herhangi bir hastalığı bulunmayan, 40 hastanın sağ gözlerinin verileri dahil edilmiştir. Hastaların SD-OKT ile cerrahi öncesi, cerrahi sonrası 1. saat ve cerrahi sonrası 3. haftada elde edilen GHK, SLK ve SMK değerleri karşılaştırılmıştır.Bulgular: Hastaların ortalama yaşı 27,54±5,99 yıl (18-45 yıl) idi. Hastaların ortalama GHK, SLK ve SMK değerleri sırasıyla cerrahi öncesi 18,43±6,03 μm, 107,90±9,01 μm, 234,3±21,2 μm, cerrahi sonrası 1. saatte 18,05±5,93 μm, 108,08±8,92 μm, 230,1±22,6 μm ve cerrahi sonrası 3. haftada 17,86±5,27 μm, 107,98±10,13 μm, 236,3±25,1 μm idi (p değerleri sırasıyla 0,159, 0,851, 0,254).Sonuç: Femtosaniye LASIK cerrahisi sonrası erken dönemde SD-OKT ile değerlendirilen GHK, SLK ve SMK değerlerinde değişiklik olmamaktadır.

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Cite This Article

ÖZÜLKEN, K., İLHAN, Ç. (2022). Evaluation of Retinal Ganglion Cell Layer Thickness in the Early Period After Femtosecond LASIK Surgery. Türk Oftalmoloji Dergisi, Cilt: 50 - Sayı: 4, 211–215. https://ajindex.com/articles/637664

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References (14)

  1. Lume M, Salgado R, Vaz F, Pinto MC, Furtado MJ, Reimao P. RNFL thickness after Lasik, LASEK and PRK. Ophthalmology Times Europe. 2009;1
  2. Hernandez-Verdejo JL, Teus MA, Román JM, Bolívar G. Porcine model to compare real-time intraocular pressure during LASIK with a mechanical microkeratome and femtosecond laser. Inveest Ophthalmol Vis Sci. 2007;48:68-72
  3. Shrivastava A, Madu A, Schultz J. Refractive surgery and the glaucoma patient. Curr Opin Ophthalmol. 2011;22:215-221
  4. Pablo LE, Ferrera A. Imaging of the retinal fiber layer with spectral domain optical coherence tomography in patients with glaucoma. Eur Ophthalmic Rev. 2010;4:17-20
  5. Citirik M, Ilhan C, Teke MY. Optical Coherence Tomography. Current Retina. 2017;1:58-68
  6. Arthur SN, Smith SD, Wright MM, Grajewski AL, Wang Q, Terry JM, Lee MS. Reproducibility and agreement in evaluating retinal nerve fibre layer thickness between Stratus and Spectralis OCT. Eye (Lond). 2011;25:192-200
  7. Zhang J, Zhou Y, Zheng Y, Liu Q, Zhai C, Wang Y. Effect of suction on macular and retinal nerve fiber layer thickness during femtosecond lenticule extraction and femtosecond laser-assisted laser in situ keratomileusis. Cataract Refract Surg. 2014;40:1994-2001
  8. Schuman JS, Pedut-Kloizman T, Hertzmark E, Hee MR, Wilkins JR, Coker JG, Puliafito CA, Fujimoto JG, Swanson EA. Reproducibility of nerve fiber layer thickness measurements using optical coherence tomography. Ophthalmology. 1996;103:1889-1898
  9. Gürses- Özden R, Pons ME, Barbieri C, Ishikawa H, Buxton DF, Liebmann JM, Ritch R. Scanning laser polarimetry measurements after laser-assisted in situ keratomileusis. Am J Ophthalmol. 2000;129:461-464
  10. Hosny M, Zaki RM, Ahmed RA, Khalil N, Mostafa HM. Changes in retinal nerve fiber layer thickness following mechanical microkeratome-assisted versus femtosecond laser-assisted LASIK. Clin Ophthalmol. 2013;7:1919- 1922
  11. Whitson JT, McCulley JP, Cavanagh HD, Song J, Bowman RW, Hertzog L. Effect of laser in situ keratomileusis on optic nerve head topography and retinal nerve fiber layer thickness. J Cataract Refract Surg. 2003;29: 2302- 2305
  12. Tsai YY, Lin JM. Effect of laser-assisted in situ keratomileusis on the retinal nerve fiber layer. Retina. 2000;20:342-345
  13. Tan O, Chopra V, Lu ATH. Detection of macular ganglion cell loss in glaucoma by Fourier-domain optical coherence tomography. Ophthalmology. 2009;116:230514.e1-2
  14. Mwanza JC, Oakley JD, Budenz DL, Chang RT, Knight OJ, Feuer WJ. Macula