Journals / Türk Oftalmoloji Dergisi / 2020 / Cilt: 50 - Sayı: 6

Prognostic Factors Affecting Graft Survival in Patients Undergoing Penetrating Keratoplasty for Infectious Keratitis

Enfeksiyöz Keratit Nedeniyle Penetran KeratoplastiYapılan Olgularda Greft Sağkalımına Etki EdenPrognostik Faktörler

Pages
324–331
Publication Date
2022-11-06
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Therapeutic success was achieved in 47 patients (79.7%) and there was a significantrelationship between therapeutic success and re-keratoplasty and early re-keratoplasty (p

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Objective & Hypothesis:Objectives: To evaluate the prognostic factors affecting graft survival in patients undergoing penetrating keratoplasty (PKP) forinfectious keratitis.
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Key Findings & Data:Materials and Methods: Patients who underwent PKP for keratitis in our hospital between 2013 and 2018 were retrospectivelyreviewed.
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Conclusion & Impact:Therapeutic success was achieved in 47 patients (79.7%) and there was a significantrelationship between therapeutic success and re-keratoplasty and early re-keratoplasty (p
🔬Design:Review & Systematic Survey
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: To evaluate the prognostic factors affecting graft survival in patients undergoing penetrating keratoplasty (PKP) forinfectious keratitis. Materials and Methods: Patients who underwent PKP for keratitis in our hospital between 2013 and 2018 were retrospectivelyreviewed. Patients who underwent therapeutic PKP at the inflammatory stage and were followed for at least 12 months were includedin the study. Age, gender, follow-up period, time between diagnosis and surgery, lens status, presence of limbal involvement, presence ofcorneal ulceration, perforation, or corneal abscess, type of microorganism detected in culture, number of fortified medications used beforesurgery and duration of use, preoperative and postoperative visual acuity, postoperative graft transparency, postoperative complications, recurrence of infection, rate of re-keratoplasty, and indication for and timing of re-keratoplasty were recorded. The relationship between these findingsand anatomic, therapeutic, and functional success were evaluated. Results: Fifty-nine patients were included in the study; 40 (67.8%) were male and 19 (32.2%) were female, and the mean age was 59.78±19.46 (6- 91) years. Anatomic success was achieved in 58 patients (98.3%). Therapeutic success was achieved in 47 patients (79.7%) and there was a significantrelationship between therapeutic success and re-keratoplasty and early re-keratoplasty (p

Özet

Amaç: Enfeksiyöz keratit nedeniyle penetran keratoplasti (PKP) yapılan olgularda greft sağkalımına etki eden prognostik faktörleri değerlendirmektir.Gereç ve Yöntem: 2013-2018 yılları arasında hastanemizde keratit sebebiyle PKP uygulanan olgular retrospektif olarak tarandı. İnflame evrede terapötik amaçlı PKP yapılan ve en az 12 ay boyunca takip edilen olgular çalışmaya dahil edildi. Hastaların yaşı, cinsiyeti, takip süresi, tanı ile cerrahi arası geçen süre, lens durumu, limbal tutulum varlığı, korneal ülserasyon, perforasyon veya korneal apse varlığı, kültürde tespit edilen mikroorganizma türü, ameliyat öncesi kullanılan fortifiye ilaç sayısı ve kullanım süresi, ameliyat öncesi ve sonrası görme keskinliği, ameliyat sonrası greft saydamlığı, ameliyat sonrası komplikasyonlar, enfeksiyon tekrarı olup olmadığı, rekeratoplasti yapılıp yapılmadığı, rekeratoplasti sebebi ve rekeratoplasti olma zamanı kaydedildi. Bu bulgularla anatomik, terapötik ve fonksiyonel başarı arasındaki ilişki değerlendirildi.Bulgular: Çalışmaya dahil edilen 59 hastanın 40’ı (%67,8) erkek, 19’u (%32,2) kadın olup, yaş ortalaması 59,78±19,46 (6-91) idi. Elli sekiz (%98,3) hastada anatomik başarı sağlandı. Terapötik başarı sağlanan hasta sayısı 47 (%79,7) olup rekeratoplasti yapılması ve rekeratoplastinin erken dönemde yapılmasıyla terapötik başarı arasında anlamlı ilişki saptandı (her ikisi için p

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Cite This Article

GENÇ, S., TAŞKAPILI, M., KIRGIZ, A., YILDIZ, B. K., YILDIRIM, Y., BEŞEK, N. K., GÜMÜŞ, G. (2022). Prognostic Factors Affecting Graft Survival in Patients Undergoing Penetrating Keratoplasty for Infectious Keratitis. Türk Oftalmoloji Dergisi, Cilt: 50 - Sayı: 6, 324–331. https://ajindex.com/articles/637645

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