Journals / Türk Oftalmoloji Dergisi / 2021 / Cilt: 51 - Sayı: 4

Donor Cornea Use in Scleral Surface Reconstruction

Skleral Yüzey Rekonstrüksiyonunda Donör Kornea Kullanımı

Pages
192–198
Publication Date
2022-11-06
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The effectiveness and safety of this method should be investigated with large patient series and long follow-up times

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: To investigate the indications for and results of treating scleral surface problems with donor corneal grafts that are not used in keratoplasty surgery or are left over from keratoplasty.
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Key Findings & Data:Materials and Methods: The records of 16 patients in whom corneal tissue was used to repair a scleral tissue defect or cover an exposed glaucoma drainage implant were evaluated retrospectively.
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Conclusion & Impact:The effectiveness and safety of this method should be investigated with large patient series and long follow-up times
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: To investigate the indications for and results of treating scleral surface problems with donor corneal grafts that are not used in keratoplasty surgery or are left over from keratoplasty. Materials and Methods: The records of 16 patients in whom corneal tissue was used to repair a scleral tissue defect or cover an exposed glaucoma drainage implant were evaluated retrospectively. Partial-thickness grafts were prepared using a combined microkeratome system with artificial anterior chamber in 10 eyes and by manual dissection in 3 eyes. Full-thickness grafts were used in 3 eyes. Results: There were 8 female and 8 male patients aged 5-79 years (mean: 39.37±24.68). Indications for the use of corneal tissue on the scleral surface were limbal dermoid excision (n=2), pterygium surgery (n=1), intraocular lens removal and scleral fixation intraocular lens (SFIOL) implantation (n=1), exposed SFIOL suture coverage (n=1), trauma (n=2), scleral tissue loss due to repeated glaucoma surgeries (n=5), and exposed glaucoma drainage implant (n=4). The patients were followed for 6-42 months (mean: 14.37±9.14). None of the patients had graft infection, thinning, immunological graft rejection, or vision loss during follow-up. Tectonic lamellar grafts did not adversely affect final visual acuity in any case. At final examination, a good combination of graft and recipient tissue, a smooth ocular surface, and a cosmetic appearance were achieved in all eyes. Conclusion: Donor corneas that are not suitable for corneal transplantation or left over from the cornea transplant can be used in patients with scleral tissue loss due to various pathologies and in the treatment of glaucoma drainage implant erosion. In these cases, the use of corneal grafts provides a good ocular surface restoration and cosmetic appearance. The effectiveness and safety of this method should be investigated with large patient series and long follow-up times

Özet

Amaç: Keratoplasti ameliyatında kullanılmayan veya keratoplastiden arta kalan donör kornea greftlerinin skleral yüzey problemlerinin tedavisinde kullanım endikasyonları ve sonuçlarını araştırmak. Gereç ve Yöntem: Skleral doku defektini kapatmak ve açıkta kalan glokom drenaj implantının üzerini örtmek için korneal doku kullanılan 16 olgunun dosyaları retrospektif olarak incelendi. Parsiyel kalınlık greftler 10 gözde yapay ön kamara ile kombine mikrokeratom sistemi kullanılarak, 3 gözde bıçakla diseke edilerek manuel olarak hazırlandı. Üç gözde tam kalınlık greft kullanıldı. Bulgular: Sekiz kadın, 8 erkek olgu 5-79 [ortalama (ort); 39,37±24,68] yaş arasında idi. Skleral yüzeyde korneal doku kullanımı için endikasyonlar; limbal dermoid eksizyonu (n=2), pterjiyum cerrahisi (n=1), göz içi lens (GİL) çıkarımı ve skleral fiksasyon göz içi lensi (SFGİL) implantasyonu (n=1), açıkta kalmış SFGİL sütürünün örtülmesi (n=1), travma (n=2), tekrarlayan glokom cerrahileri nedeniyle skleral doku kayıpları (n=5) ve açıkta kalmış glokom drenaj implantı (n=4) idi. Olgular 6-42 (ort; 14,37±9,14) ay takip edildi. Takip süresi boyunca hiçbir olguda greft enfeksiyonu, incelmesi, immünolojik greft rejeksiyonu ve görme kaybı izlenmedi. Tektonik lameller greft hiçbir olguda sonuç görme keskinliğini olumsuz etkilemedi. Sonuç muayenede tüm gözlerde greft alıcı doku ile iyi bir birleşme gösterdi, düzgün bir oküler yüzey ve kozmetik görünüm elde edildi. Sonuç: Kornea nakli için uygun olmayan veya kornea naklinden arta kalan donör kornealar çeşitli patolojilerden kaynaklanan skleral doku kayıplarında ve glokom drenaj implant erezyonlarının tedavisinde kullanılabilir. Bu olgularda korneal greft kullanımı iyi bir oküler yüzey restorasyonu ve kozmetik görünüm sağlamaktadır. Yöntemin etkili ve emniyetli olduğu geniş hasta serileri ve uzun takip süreleri ile araştırılmalıdır

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Cite This Article

ÖZDEMİR, E. Ş., BURCU, A., AKKAYA, Z. Y., UZMAN, S. Ö. (2022). Donor Cornea Use in Scleral Surface Reconstruction. Türk Oftalmoloji Dergisi, Cilt: 51 - Sayı: 4, 192–198. https://ajindex.com/articles/637579

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