Journals / Türk Nöroloji Dergisi / 2011 / Cilt: 17 - Sayı: 3

Parkinsonism associated with chronic liver disease: Case report

Kronik karaciğer hastalığıyla ilişkili parkinsonizm: Olgu sunumu

Pages
150–153
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here, because of its rarity, we report a patient with parkinsonian symptoms resulting from liver disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Patients with chronic liver disease may suffer from neurological abnormalities secondary to hepatocerebral degeneration.
📊
Key Findings & Data:Among these neurological abnormalities, the extrapyramidal symptoms are seen more often.
💡
Conclusion & Impact:Here, because of its rarity, we report a patient with parkinsonian symptoms resulting from liver disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Patients with chronic liver disease may suffer from neurological abnormalities secondary to hepatocerebral degeneration. Among these neurological abnormalities, the extrapyramidal symptoms are seen more often. Extrapyramidal involvement accompanied with hepatic encephalopathy has been reported rarely in the literature. The mechanism for these symptoms is the accumulation of substances such as manganese and ammonia in the basal ganglia. Here, because of its rarity, we report a patient with parkinsonian symptoms resulting from liver disease.

Özet

Kronik karaciğer hastalığı olan hastalarda, hepatoserebral dejenerasyona bağlı kalıcı nörolojik anormallikler ortaya çıkabilir. Bu nörolojik anormalliklerden daha sık görüleni ekstrapiramidal bulgulardır. Hepatik ensefalopati ataklarına eşlik eden ekstrapiramidal tutulum literatürde nadir olarak bildirilmiştir. Bu semptomlara neden olan mekanizma, manganez ve amonyak gibi maddelerin bazal gangliyonlarda birikmesidir. Burada, kronik karaciğer hastalığına bağlı parkinsonizm bulgularıyla ortaya çıkan olgu, nadir rastlanması nedeniyle sunuldu.

🔖

Cite This Article

ERDOĞAN, F., AKGÜL, N., MİRZA, M., İSMAİLOĞULLARI, S., ERSOY, Ö. A. (2022). Parkinsonism associated with chronic liver disease: Case report. Türk Nöroloji Dergisi, Cilt: 17 - Sayı: 3, 150–153. https://ajindex.com/articles/636961

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Türkel Y, Terzi M, Yazıcı T, Sandıkçı U, Cengiz N. Parkinsonizm le ortaya çıkan kronik karaciğer sirozu: iki olgu sunumu. Parkin son Hast Harek Boz Derg 2009;12:25-9
  2. Victor M, Adams R, Cole M. The acquired (non-Wilsonian) type of chronic hepatocerebral degeneration. Medicine 1965;44:345-96
  3. Weissenborn K, Kolbe H. The basal ganglia and portal-systemic encephalopathy. Metab Brain Dis 1998;13:261-72
  4. Jog M, Lang A. Chronic acquired hepatocerebral degeneration: case reports and new insights. Mov Disord 1995;10:714-22
  5. Burkhard PR, Delavelle J, Du Pasquier R, Spahr L. Chronic par kinsonism associated with cirrhosis: a distinct subset of acqu ired hepatocerebral degeneration. Arch Neurol 2003;60:521-8
  6. Lee J, Lacomis D, Comu S, Jacobsohn J, Kanal E. Acquired he patocerebral degeneration: MR and pathologic findings. AJNR Am J Neuroradiol 1998;19:485-7
  7. Lewis M, Howdle PD. The neurology of liver failure. QJM 2003;96:623-33
  8. Chen WX, Wang P, Yan SX, Li YM, Yu CH, Jiang LL. Acquired hepatocerebral degeneration: a case report. World J Gastroen terol 2005;11:764-6
  9. Noone ML, Kumar VG, Ummer K, Achambat L, Salam KA. Cirr hosis presenting as parkinsonism. Ann Indian Acad Neurol 2008;11:179-81
  10. Spahr L, Butterworth R, Fontaine S, Bui L, Therrien G, Milette PC, et al. Increased blood manganese in cirrhotic patients: re lationship to pallidal magnetic signal hyperintensity and neuro logical symptoms. Hepatology 1996;24:1116-20
  11. Hauser R, Zesiewicz T, Rosemurgy A, Martinez C, Olanow C. Manganese intoxication and chronic liver failure. Ann Neurol 1994;36:871-5
  12. Aytaç E, Aldemir A, Çomoğlu S. Karaciğer hastalığına bağlı ola rak gelişen bir parkinsonizm olgusu. Parkinson Hast Harek Boz Derg 2010;13:12-4
  13. Rocha AJ, Braga FT, Silva CJ, Maia AC Jr, Mourão GS, Gagliar di RJ. Reversal of parkinsonism and port systemic encephalo pathy following embolization of a congenital intrahepatic ve nous shunt: brain MR imaging and 1H spectroscopic findings. Am J Neuroradiol 2004;25:1247-50
  14. Lazeyras F, Spahr L, DuPasquier R, Delavelle J, Burkhard P, Ha denque A, et al. Persistence of mild parkinsonism 4 months af ter liver transplantation in patients with preoperative minimal hepatic encephalopathy: a study on neuroradiological and blo od manganese changes. Transpl Int 2002;15:188-95
  15. Klos KJ, Ahlskog JE, Josephs KA, Fealey RD. Neurologic spect rum of chronic liver failure and basal ganglia T1 hyperintensity on magnetic resonance imaging: p