Journals / Türk Nöroloji Dergisi / 2021 / Cilt: 27 - Sayı: 1

Retinal Thickness Alterations in Patients with Migraine

Migren Hastalarındaki Retina Kalınlık Değişiklikleri

Pages
69–74
Publication Date
2022-11-06
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The central macular thickness, inner inferior macular thickness, central quadrant of macular RNFL thickness, mean of outer segment GCL thickness, inner inferior and temporal, mean of outer nasal quadrant GCL thickness measurements were found to be thinner in both aura (+) and aura (-) patients with migraine when compared with healthy subjects (p

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Objective & Hypothesis:Objective: To investigate the alterations in macula, ganglion cell complex (GCC), ganglion cell layer (GCL), macular and peripapillary retinal nerve fiber layer (pRNFL) thickness values in patients with migraine and to elicit the correlation between thickness and clinical characteristics of migraine disease.
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Key Findings & Data:Materials and Methods: One hundred sixty-two eyes of 81 patients with migraine (76 eyes of 38 patients with aura and 86 eyes of 43 patients without aura) and 90 eyes of 45 healthy volunteers as the control group were recruited in the study.
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Conclusion & Impact:The central macular thickness, inner inferior macular thickness, central quadrant of macular RNFL thickness, mean of outer segment GCL thickness, inner inferior and temporal, mean of outer nasal quadrant GCL thickness measurements were found to be thinner in both aura (+) and aura (-) patients with migraine when compared with healthy subjects (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To investigate the alterations in macula, ganglion cell complex (GCC), ganglion cell layer (GCL), macular and peripapillary retinal nerve fiber layer (pRNFL) thickness values in patients with migraine and to elicit the correlation between thickness and clinical characteristics of migraine disease. Materials and Methods: One hundred sixty-two eyes of 81 patients with migraine (76 eyes of 38 patients with aura and 86 eyes of 43 patients without aura) and 90 eyes of 45 healthy volunteers as the control group were recruited in the study. Macula, GCL, GCC, and RNFL thickness values were measured using optical coherence tomography (OCT). Results: The mean ages of the aura (+) group, aura (-) group, and the control group were 32.5±7.7, 35.2±7.9, and 33.7±7.7 years, respectively (p=0.751). The mean follow-up time of patients with migraine were 6.3±3.1 years. The central macular thickness, inner inferior macular thickness, central quadrant of macular RNFL thickness, mean of outer segment GCL thickness, inner inferior and temporal, mean of outer nasal quadrant GCL thickness measurements were found to be thinner in both aura (+) and aura (-) patients with migraine when compared with healthy subjects (p

Özet

Amaç: Migren hastalarında makula, gangliyon hücre kompleksi (GHK), gangliyon hücre tabakası (GHT), makular ve peripapiller retina sinir lifi tabakası (pRSLT) kalınlığı değişikliklerini incelemek ve kalınlıklar ile migren hastalığının klinik özellikleri arasındaki ilişkiyi ortaya çıkarmaktır. Gereç ve Yöntem: Çalışmaya 81 migren hastasının 162 gözü (38 auralı hastanın 76 gözü) ve 43 aurasız hastanın 86 gözü ve kontrol grubu olarak 45 sağlıklı gönüllünün 90 gözü dahil edildi. Makula, GHT, GHK ve RSLT kalınlık değerleri optik koherens tomografi (OKT) ile ölçüldü. Bulgular: Yaş ortalaması aura (+) grup, aura (-) grup ve kontrol grubu için sırasıyla 32,5±7,7, 35,2±7,9 ve 33,7±7,7 yıldı (p=0,751). Hastalar ortalama 6,3±3,1 yıldır migren tanısı ile takip edilmekte idi. Sağlıklı bireylerle karşılaştırıldığında hem aura (+) hem aura (-) migren hastalarında santral makula kalınlığı, iç inferior makula kalınlığı, santral makular RSLT kalınlığı, ortalama dış halka GHT kalınlığı ile iç inferior, iç temporal ve dış nazal GHT kalınlıkları; inferiotemporal pRSLT kalınlığı (p

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Cite This Article

EYİDOĞAN, D., YURTOĞULLARI, Ş., TİMUR, İ. E. E. (2022). Retinal Thickness Alterations in Patients with Migraine. Türk Nöroloji Dergisi, Cilt: 27 - Sayı: 1, 69–74. https://ajindex.com/articles/655041

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