Kronik karaciğer hastalığıyla ilişkili parkinsonizm: Olgu sunumu

Kronik karaciğer hastalığı olan hastalarda, hepatoserebral dejenerasyona bağlı kalıcı nörolojik anormallikler ortaya çıkabilir. Bu nörolojik anormalliklerden daha sık görüleni ekstrapiramidal bulgulardır. Hepatik ensefalopati ataklarına eşlik eden ekstrapiramidal tutulum literatürde nadir olarak bildirilmiştir. Bu semptomlara neden olan mekanizma, manganez ve amonyak gibi maddelerin bazal gangliyonlarda birikmesidir. Burada, kronik karaciğer hastalığına bağlı parkinsonizm bulgularıyla ortaya çıkan olgu, nadir rastlanması nedeniyle sunuldu.

Abstract

Patients with chronic liver disease may suffer from neurological abnormalities secondary to hepatocerebral degeneration. Among these neurological abnormalities, the extrapyramidal symptoms are seen more often. Extrapyramidal involvement accompanied with hepatic encephalopathy has been reported rarely in the literature. The mechanism for these symptoms is the accumulation of substances such as manganese and ammonia in the basal ganglia. Here, because of its rarity, we report a patient with parkinsonian symptoms resulting from liver disease.

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Bu Makaleye Atıf Yap

ERDOĞAN, F., AKGÜL, N., MİRZA, M., İSMAİLOĞULLARI, S., ERSOY, Ö. A. (2022). Kronik karaciğer hastalığıyla ilişkili parkinsonizm: Olgu sunumu. Türk Nöroloji Dergisi, Cilt: 17 - Sayı: 3, 150–153. https://ajindex.com/articles/636961

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